2. Gene
  3. RAP2B - RAP2B, member of RAS oncogene family Gene

RAP2B - RAP2B, member of RAS oncogene family Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 5912 | Gene type: protein coding

About RAP2B

Cytogenetic location: 3q25.2 Genomic coordinates (GRCh38): 3:153,162,226-153,170,627 (from NCBI)

This gene has 1 transcript (splice variant), 184 orthologues and 35 paralogues.

Summary

This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical Ras proteins and have numerous structural features in common. The most striking difference between the RAP and Ras proteins resides in their 61st amino acid: glutamine in Ras is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008]

RAP2B Products(1)

mRNA Protein Name
NM_002886.4 NP_002877.2 ras-related protein Rap-2b

RAP2B Protein Structure

Ras

Ras: Ras family (5 - 164)

  • 0
  • 100
  • 183 a.a.
Protein Preferred Names Protein Names

ras-related protein Rap-2b

small GTP binding protein

Related Diseases

Diseases Alias
Smith-Mccort Dysplasia 1

Smith-Mccort Dysplasia

SMC1

Smc

Smith Mccort Dysplasia

Smith-Mccort Dwarfism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11658 RAP2B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RAP2B VGNC VGNC:33720
Felis catus RAP2B VGNC VGNC:69238
Macaca mulatta RAP2B VGNC VGNC:76660
Mus musculus RAP2B MGD MGI:1921262
Canis familiaris RAP2B VGNC VGNC:52900
Rattus norvegicus RAP2B RGD RGD:620591