SYT17 - synaptotagmin 17 Gene

Homo sapiens

Also known as Syt-17; sytXVII

Gene ID: 51760 | Gene type: protein coding

About SYT17

This gene has 9 transcripts (splice variants), 160 orthologues and 31 paralogues. Broad expression in brain (RPKM 8.9), prostate (RPKM 3.0) and 15 other tissues.

Summary

Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in positive regulation of dendrite extension. Predicted to be located in trans-Golgi network. Predicted to be active in exocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SYT17 Products(4)

mRNA	Protein	Name
NM_001308157.2	NP_001295086.1	synaptotagmin-17 isoform 2
NM_001330509.2	NP_001317438.1	synaptotagmin-17 isoform 3
NM_001410903.1	NP_001397832.1	synaptotagmin-17 isoform 4
NM_016524.4	NP_057608.2	synaptotagmin-17 isoform 1

SYT17 Protein Structure

0
100
200
300
400
474 a.a.

Protein Preferred Names

Protein Names

synaptotagmin-17

B/K protein

Related Diseases

Diseases

Alias

Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2b

Lgmd2b	Lgmd3
Limb-Girdle Muscular Dystrophy Due To Dysferlin Deficiency	Limb-Girdle Muscular Dystrophy Type 3
Muscular Dystrophy, Limb-Girdle, Type 2b

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14113	SYT17 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SYT17	VGNC	VGNC:78200
Mus musculus	SYT17	MGD	MGI:104966
Rattus norvegicus	SYT17	RGD	RGD:708576
Bos taurus	SYT17	VGNC	VGNC:35540
Felis catus	SYT17	VGNC	VGNC:65897

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