ZNF438 - zinc finger protein 438 Gene

Also Known as bA330O11.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 220929

Summary

Enables DNA-binding transcription factor activity. Involved in negative regulation of DNA-templated transcription. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in thyroid (RPKM 2.5), testis (RPKM 2.0) and 24 other tissues.

ZNF438 Products (10)

mRNA Protein Name
NM_001143766.2 NP_001137238.1 zinc finger protein 438 isoform a
NM_001143767.2 NP_001137239.1 zinc finger protein 438 isoform a
NM_001143768.2 NP_001137240.1 zinc finger protein 438 isoform a
NM_001143769.2 NP_001137241.1 zinc finger protein 438 isoform c
NM_001143770.2 NP_001137242.1 zinc finger protein 438 isoform b
NM_001143771.2 NP_001137243.1 zinc finger protein 438 isoform b
NM_001387405.1 NP_001374334.1 zinc finger protein 438 isoform a
NM_001387411.1 NP_001374340.1 zinc finger protein 438 isoform a
NM_001387412.1 NP_001374341.1 zinc finger protein 438 isoform a
NM_182755.3 NP_877432.1 zinc finger protein 438 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
17669267 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
17669267 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17669267 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF438 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF438 Q7Z4V0 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 PIH1D2 Homo sapiens Q8WWB5
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 LGALS14 Homo sapiens Q8TCE9
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 MORF4L1 Homo sapiens Q9UBU8-2
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 FXR1 Homo sapiens P51114-2
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 FXR1 Homo sapiens P51114-2
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 ZNF526 Homo sapiens Q8TF50
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 ZNF526 Homo sapiens Q8TF50
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 ZNF526 Homo sapiens Q8TF50
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 BANP Homo sapiens Q8N9N5-2
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 NEK6 Homo sapiens Q9HC98-4
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 KCTD7 Homo sapiens Q96MP8-2
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 HAPLN2 Homo sapiens Q9GZV7
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 BBC3 Homo sapiens Q96PG8
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 SSX2IP Homo sapiens Q9Y2D8
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 SSX2IP Homo sapiens Q9Y2D8
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 ZNF143 Homo sapiens P52747
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 PNMA1 Homo sapiens Q8ND90
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 PNMA1 Homo sapiens Q8ND90
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 PNMA1 Homo sapiens Q8ND90
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 MCC Homo sapiens P23508
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 PRMT7 Homo sapiens Q9NVM4
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 RPP25 Homo sapiens Q9BUL9
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 NXF1 Homo sapiens Q9UBU9
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 RABEP1 Homo sapiens Q15276
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 RABEP1 Homo sapiens Q15276
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 DPH3 Homo sapiens Q96FX2
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 CDCA7L Homo sapiens Q96GN5
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 MRPL11 Homo sapiens Q9Y3B7
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 MYLIP Homo sapiens Q8WY64
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 CEP19 Homo sapiens Q96LK0
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 ZBTB8A Homo sapiens Q96BR9
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 TSGA10 Homo sapiens Q9BZW7
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 TSGA10 Homo sapiens Q9BZW7
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 TSGA10 Homo sapiens Q9BZW7
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 SYT17 Homo sapiens Q9BSW7
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 MAGOHB Homo sapiens Q96A72
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
ZNF438 Q7Z4V0 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
ZNF438 Q7Z4V0 TBC1D22B Homo sapiens Q9NU19
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 DMRT3 Homo sapiens Q9NQL9
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 TRIM50 Homo sapiens Q86XT4
Validated Y2H
32296183
Intra
ZNF438 Q7Z4V0 ZNF629 Homo sapiens Q9UEG4
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16140 ZNF436 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16161 ZNF638 Human Pre-designed siRNA Set A Pre-designed Set / Unkown