CDCA7L - cell division cycle associated 7 like Gene

Also Known as R1; JPO2; RAM2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55536

About CDCA7L

Cytogenetic location: 7p15.3 Genomic coordinates (GRCh38): 7:21,900,899-21,945,899 (from NCBI)

This gene has 10 transcripts (splice variants), 198 orthologues and 1 paralogue. Broad expression in thyroid (RPKM 17.0), bone marrow (RPKM 16.5) and 25 other tissues.

Summary

Acts upstream of or within positive regulation of cell population proliferation. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CDCA7L Products (3)

mRNA Protein Name
NM_001127370.3 NP_001120842.1 cell division cycle-associated 7-like protein isoform 2
NM_001127371.3 NP_001120843.1 cell division cycle-associated 7-like protein isoform 3
NM_018719.5 NP_061189.2 cell division cycle-associated 7-like protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24705354 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
15994933 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15994933 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDCA7L Protein Structure

zf-4CXXC_R1

zf-4CXXC_R1: Zinc-finger domain of monoamine-oxidase A repressor R1 (344 - 443)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 454 a.a.
Protein Preferred Names Protein Names

cell division cycle-associated 7-like protein

  • transcription factor RAM2

CDCA7L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CDCA7L Q96GN5 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
CDCA7L Q96GN5 FAM9B Homo sapiens Q8IZU0
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 ZNF250 Homo sapiens P15622-3
Y2H Array
25416956
Intra
CDCA7L Q96GN5 TFPT Homo sapiens P0C1Z6-2
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 TFPT Homo sapiens P0C1Z6-2
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 TFPT Homo sapiens P0C1Z6-2
Y2H Array
25416956
Intra
CDCA7L Q96GN5 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 ZGPAT Homo sapiens Q8N5A5-2
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ZGPAT Homo sapiens Q8N5A5-2
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 SSX1 Homo sapiens Q16384
Y2H Array
32296183
Intra
CDCA7L Q96GN5 SSX1 Homo sapiens Q16384
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PPP1R16B Homo sapiens Q96T49
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 PPP1R16B Homo sapiens Q96T49
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 PPP1R16B Homo sapiens Q96T49
Y2H Array
25416956
Intra
CDCA7L Q96GN5 MFAP1 Homo sapiens P55081
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
Intra
CDCA7L Q96GN5 PIP4K2B Homo sapiens P78356-2
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PIP4K2B Homo sapiens P78356-2
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ZNF438 Homo sapiens Q7Z4V0
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 ZNF438 Homo sapiens Q7Z4V0
Y2H Array
32296183
Intra
CDCA7L Q96GN5 BRPF1 Homo sapiens P55201-2
Y2H Array
32296183
Intra
CDCA7L Q96GN5 BRPF1 Homo sapiens P55201-2
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 JADE2 Homo sapiens A0A0C4DFT8
Y2H Array
32296183
Intra
CDCA7L Q96GN5 JADE2 Homo sapiens A0A0C4DFT8
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 NDUFB7 Homo sapiens P17568
Y2H Array
32296183
Intra
CDCA7L Q96GN5 NDUFB7 Homo sapiens P17568
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 PRPF31 Homo sapiens Q8WWY3
Y2H Array
25416956
Intra
CDCA7L Q96GN5 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ANKRD11 Homo sapiens X5D778
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 ANKRD11 Homo sapiens X5D778
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 FAM217B Homo sapiens Q9NTX9
Y2H Array
32296183
Intra
CDCA7L Q96GN5 FAM217B Homo sapiens Q9NTX9
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 FAM217B Homo sapiens Q9NTX9
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
25416956
Intra
CDCA7L Q96GN5 CAVIN1 Homo sapiens Q6NZI2
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 CAVIN1 Homo sapiens Q6NZI2
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ABT1 Homo sapiens Q9ULW3
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 ABT1 Homo sapiens Q9ULW3
Y2H Array
25416956
Intra
CDCA7L Q96GN5 SNRNP48 Homo sapiens Q6IEG0
Y2H Array
32296183
Intra
CDCA7L Q96GN5 SNRNP48 Homo sapiens Q6IEG0
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 EIF4A3 Homo sapiens P38919
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 PBX1 Homo sapiens P40424
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PBX1 Homo sapiens P40424
Y2H Array
32296183
Intra
CDCA7L Q96GN5 MCRS1 Homo sapiens Q96EZ8
Y2H Array
32296183
Intra
CDCA7L Q96GN5 MCRS1 Homo sapiens Q96EZ8
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PBX2 Homo sapiens P40425
Y2H Array
32296183
Intra
CDCA7L Q96GN5 PBX2 Homo sapiens P40425
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 BAG5 Homo sapiens Q9UL15
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 BAG5 Homo sapiens Q9UL15
Y2H Array
32296183
Intra
CDCA7L Q96GN5 BAG5 Homo sapiens Q9UL15
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 NOP2 Homo sapiens P46087
Y2H Array
25416956
Intra
CDCA7L Q96GN5 PIH1D1 Homo sapiens Q9NWS0
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 PIH1D1 Homo sapiens Q9NWS0
Y2H Array
32296183
Intra
CDCA7L Q96GN5 PIH1D1 Homo sapiens Q9NWS0
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra
CDCA7L Q96GN5 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 PRDM14 Homo sapiens Q9GZV8
Y2H Array
25416956
Intra
CDCA7L Q96GN5 PRDM14 Homo sapiens Q9GZV8
Y2H Array
32296183
Intra
CDCA7L Q96GN5 PRDM14 Homo sapiens Q9GZV8
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 PRDM14 Homo sapiens Q9GZV8
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 DMAP1 Homo sapiens Q9NPF5
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 DMAP1 Homo sapiens Q9NPF5
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 DMAP1 Homo sapiens Q9NPF5
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ZNF620 Homo sapiens Q6ZNG0
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ZNF620 Homo sapiens Q6ZNG0
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 ING5 Homo sapiens Q8WYH8
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
25416956
Intra
CDCA7L Q96GN5 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 ANKRD1 Homo sapiens Q15327
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ANKRD1 Homo sapiens Q15327
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 ANKRD23 Homo sapiens Q86SG2
Y2H Array
32296183
Intra
CDCA7L Q96GN5 ANKRD23 Homo sapiens Q86SG2
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
CDCA7L Q96GN5 PPP1R16A Homo sapiens Q96I34
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 PPP1R16A Homo sapiens Q96I34
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PPP1R16A Homo sapiens Q96I34
Y2H Array
32296183
Intra
CDCA7L Q96GN5 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CDCA7L Q96GN5 UTP3 Homo sapiens Q9NQZ2
Y2H Array
25416956
Intra
CDCA7L Q96GN5 STX11 Homo sapiens O75558
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 STX11 Homo sapiens O75558
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 NOL12 Homo sapiens Q9UGY1
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 NOL12 Homo sapiens Q9UGY1
Y2H Array
32296183
Intra
CDCA7L Q96GN5 NOL12 Homo sapiens Q9UGY1
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 RRP7A Homo sapiens Q9Y3A4
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 RRP7A Homo sapiens Q9Y3A4
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 MRPL28 Homo sapiens Q13084
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 MRPL28 Homo sapiens Q13084
Y2H Array
32296183
Intra
CDCA7L Q96GN5 MDFI Homo sapiens Q99750
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 MDFI Homo sapiens Q99750
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
CDCA7L Q96GN5 MDFI Homo sapiens Q99750
Y2H Array
25416956
Intra
CDCA7L Q96GN5 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
CDCA7L Q96GN5 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 ZNF821 Homo sapiens O75541
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 TADA2A Homo sapiens O75478
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 MLH1 Homo sapiens P40692
Y2H Pooling
27229929
Intra
CDCA7L Q96GN5 CCDC116 Homo sapiens Q8IYX3
Y2H Array
32296183
Intra
CDCA7L Q96GN5 CCDC116 Homo sapiens Q8IYX3
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 TNNI1 Homo sapiens P19237
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 TNNI1 Homo sapiens P19237
Y2H Array
32296183
Intra
CDCA7L Q96GN5 CTNNBL1 Homo sapiens Q8WYA6
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 CTNNBL1 Homo sapiens Q8WYA6
Y2H Array
25416956
Intra
CDCA7L Q96GN5 CTNNBL1 Homo sapiens Q8WYA6
Y2H Prey Pooling
25416956
Intra
CDCA7L Q96GN5 CARD9 Homo sapiens Q9H257
Y2H Array
25416956
Intra
CDCA7L Q96GN5 TRAF3IP3 Homo sapiens Q9Y228
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 DAXX Homo sapiens Q9UER7
Y2H Array
25416956
Intra
CDCA7L Q96GN5 DAXX Homo sapiens Q9UER7
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
CDCA7L Q96GN5 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
CDCA7L Q96GN5 LMO1 Homo sapiens P25800
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 LMO1 Homo sapiens P25800
Y2H Array
25416956
Intra
CDCA7L Q96GN5 AVPI1 Homo sapiens Q5T686
Y2H Array
32296183
Intra
CDCA7L Q96GN5 AVPI1 Homo sapiens Q5T686
Y2H Prey Pooling
32296183
Intra
CDCA7L Q96GN5 MORN3 Homo sapiens Q6PF18
Validated Y2H
25416956
Intra
CDCA7L Q96GN5 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ciliary Dyskinesia, Primary, 7

  • Primary Ciliary Dyskinesia 7

  • CILD7

  • Ciliary Dyskinesia, Primary, 7, With Or Without Situs Inversus

  • Primary Ciliary Dyskinesia 7 With Or Without Situs Inversus

  • Ics7

  • Immotile Cilia Syndrome 7

  • Dyskinesia, Ciliary, Primary, 7
Primary Ciliary Dyskinesia

  • Immotile Cilia Syndrome

  • Kartagener Syndrome

  • Dextrocardia Bronchiectasis And Sinusitis

  • Pcd

  • Ciliary Motility Disorders

  • Ciliary Motility Disorder

  • Immotile Ciliary Syndrome

  • Ciliary Dyskinesia Primary

  • Ics

  • Polynesian Bronchiectasis

  • Dextrocardia-Bronchiectasis-Sinusitis Syndrome

  • Immotile Cilia Syndrome, Kartagener Type

  • Primary Ciliary Dyskinesia And Situs Inversus

  • Primary Ciliary Dyskinesia, Kartagener Type

  • Siewert Syndrome

  • Dyskinesia, Ciliary, Primary
Dextrocardia With Situs Inversus

  • Situs Inversus Totalis

  • Complete Situs Inversus

  • Complete Situs Inversus Viscerum

  • Situs Inversus
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Situs Inversus

  • Situs Inversus Viscerum

  • Laterality Sequence

  • Complete Transposition

  • Siv
Malignant Pineal Area Germ Cell Neoplasm

  • Pineal Germ Cell Tumor

  • Malignant Pineal Parenchymal Germ Cell Tumor

  • Pineal Region Germ Cell Tumor

  • Pineal Cell Tumor

  • Pineal Cell Tumour

  • Pineal Region Germinoma

  • Malignant Pineal Region Germ Cell Tumor

  • Pineal Germinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02316 CDCA7L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CDCA7L VGNC VGNC:39016
Mus musculus CDCA7L MGD MGI:2384982
Macaca mulatta CDCA7L VGNC VGNC:70919
Bos taurus CDCA7L VGNC VGNC:27087
Rattus norvegicus CDCA7L RGD RGD:1564080
Felis catus CDCA7L VGNC VGNC:60669
Others CDCA7L NCBI