HSF2BP - heat shock transcription factor 2 binding protein Gene

Homo sapiens

Also known as POF19; MEILB2

Gene ID: 11077 | Gene type: protein coding

About HSF2BP

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:43,444,972-43,659,488 (from NCBI)

This gene has 2 transcripts (splice variants), 197 orthologues and is associated with 1 phenotype. Biased expression in testis (RPKM 2.8), brain (RPKM 0.5) and 6 other tissues.

Summary

HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008]

HSF2BP Products(1)

mRNA	Protein	Name
NM_007031.2	NP_008962.1	heat shock factor 2-binding protein

Protein Preferred Names

Protein Names

heat shock factor 2-binding protein

meiotic localizer of BRCA2

Related Diseases

Diseases

Alias

Premature Ovarian Failure 19

POF19	Primary Ovarian Insufficiency 19
Poi19	Ovarian Failure, Premature, Type 19

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06410	HSF2BP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	HSF2BP	MGD	MGI:1921627
Canis familiaris	HSF2BP	VGNC	VGNC:41816
Macaca mulatta	HSF2BP	VGNC	VGNC:73532
Rattus norvegicus	HSF2BP	RGD	RGD:1565879
Bos taurus	HSF2BP	VGNC	VGNC:29983
Felis catus	HSF2BP	VGNC	VGNC:102757

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