C18orf54 - chromosome 18 open reading frame 54 Gene

Also Known as LAS2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 162681

Summary

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in testis (RPKM 6.1), placenta (RPKM 1.1) and 15 other tissues.

C18orf54 Products (5)

mRNA Protein Name
NM_001288980.2 NP_001275909.1 lung adenoma susceptibility protein 2 isoform a
NM_001288981.2 NP_001275910.1 lung adenoma susceptibility protein 2 isoform a
NM_001288982.2 NP_001275911.1 lung adenoma susceptibility protein 2 isoform c
NM_001370309.1 NP_001357238.1 lung adenoma susceptibility protein 2 isoform a
NM_173529.6 NP_775800.3 lung adenoma susceptibility protein 2 isoform b precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C18orf54 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LAS2 Q8IYD9 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra
LAS2 Q8IYD9 GLE1 Homo sapiens Q53GS7
Validated Y2H
32814053
Intra
LAS2 Q8IYD9 GLE1 Homo sapiens Q53GS7
Y2H Array
32814053
Intra
LAS2 Q8IYD9 GLE1 Homo sapiens Q53GS7
Y2H Pooling
32814053
Intra
LAS2 Q8IYD9 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
LAS2 Q8IYD9 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
LAS2 Q8IYD9 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
LAS2 Q8IYD9 TXLNB Homo sapiens Q8N3L3
Validated Y2H
32296183
Intra
LAS2 Q8IYD9 MAGEA11 Homo sapiens P43364
Y2H Prey Pooling
32296183
Intra
LAS2 Q8IYD9 MAGEA11 Homo sapiens P43364
Y2H Array
32296183
Intra
LAS2 Q8IYD9 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
Intra
LAS2 Q8IYD9 MAGOHB Homo sapiens Q96A72
Validated Y2H
32296183
Intra
LAS2 Q8IYD9 CNTLN Homo sapiens Q9NXG0-2
Y2H Prey Pooling
32296183
Intra
LAS2 Q8IYD9 CNTLN Homo sapiens Q9NXG0-2
Validated Y2H
32296183
Intra
LAS2 Q8IYD9 CNTLN Homo sapiens Q9NXG0-2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01701 C16orf54 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01716 C1orf54 Human Pre-designed siRNA Set A Pre-designed Set / Unkown