CCDC146 - coiled-coil domain containing 146 Gene

Also Known as MBO2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57639

About CCDC146

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:77,122,615-77,295,204 (from NCBI)

This gene has 9 transcripts (splice variants), 199 orthologues and 1 paralogue. Broad expression in testis (RPKM 14.9), skin (RPKM 7.4) and 22 other tissues.

Summary

Located in centriole. [provided by Alliance of Genome Resources, Apr 2022]

CCDC146 Products (1)

mRNA Protein Name
NM_020879.3 NP_065930.2 coiled-coil domain-containing protein 146

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in spermatid development IMP
IMP: Inferred from mutant phenotype
38441556 GOA
Cellular Component GO Annotation Evidence References Source
located in axoneme IDA
IDA: Inferred from direct assay
38441556 GOA
located in centriole IDA
IDA: Inferred from direct assay
25074808 GOA
located in centrosome IDA
IDA: Inferred from direct assay
30094225 GOA
located in ciliary basal body IDA
IDA: Inferred from direct assay
38441556 GOA
located in midbody IDA
IDA: Inferred from direct assay
38441556 GOA
located in sperm flagellum IDA
IDA: Inferred from direct assay
38441556 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 146

CCDC146 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC146 Q8IYE0 CENPH Homo sapiens Q9H3R5
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CENPH Homo sapiens Q9H3R5
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 CENPH Homo sapiens Q9H3R5
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 NECAB2 Homo sapiens Q7Z6G3-2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MAGEA6 Homo sapiens P43360
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT38 Homo sapiens O76015
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT38 Homo sapiens O76015
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT38 Homo sapiens O76015
Y2H Array
29892012
Intra
CCDC146 Q8IYE0 GAS8 Homo sapiens O95995
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 GAS8 Homo sapiens O95995
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 GRAMD4 Homo sapiens Q6IC98
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 GRAMD4 Homo sapiens Q6IC98
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 TRIML2 Homo sapiens Q8N7C3
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 TRIML2 Homo sapiens Q8N7C3
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 TRIML2 Homo sapiens Q8N7C3
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 CDR2L Homo sapiens Q86X02
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CDR2L Homo sapiens Q86X02
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 TEPSIN Homo sapiens Q96N21
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 PROSER3 Homo sapiens Q2NL68
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 PROSER3 Homo sapiens Q2NL68
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 CBY2 Homo sapiens Q8NA61-2
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 CBY2 Homo sapiens Q8NA61-2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 CBY2 Homo sapiens Q8NA61-2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 AKAP9 Homo sapiens Q6PJH3
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 AKAP9 Homo sapiens Q6PJH3
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 CDR2 Homo sapiens Q01850
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CDR2 Homo sapiens Q01850
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 KRT26 Homo sapiens Q7Z3Y9
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT26 Homo sapiens Q7Z3Y9
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 VPS28 Homo sapiens Q9UK41-2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 VPS28 Homo sapiens Q9UK41-2
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 VPS28 Homo sapiens Q9UK41-2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 N4BP3 Homo sapiens O15049
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 N4BP3 Homo sapiens O15049
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MIPOL1 Homo sapiens Q8TD10
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 PPP2R3C Homo sapiens Q969Q6
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 PPP2R3C Homo sapiens Q969Q6
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 PPP2R3C Homo sapiens Q969Q6
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 VPS52 Homo sapiens Q8N1B4
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT24 Homo sapiens Q2M2I5
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT24 Homo sapiens Q2M2I5
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MCC Homo sapiens P23508
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 SH3BP1 Homo sapiens Q9Y3L3
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 SH3BP1 Homo sapiens Q9Y3L3
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 SH3BP1 Homo sapiens Q9Y3L3
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 NUP62 Homo sapiens P37198
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 NUP62 Homo sapiens P37198
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 TXLNA Homo sapiens P40222
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 TXLNA Homo sapiens P40222
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Anti Tag CoIP
33961781
Intra
CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 GMNN Homo sapiens O75496
Y2H Array
31515488
Intra
CCDC146 Q8IYE0 NAP1L2 Homo sapiens Q9ULW6
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 NAP1L2 Homo sapiens Q9ULW6
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 NAP1L2 Homo sapiens Q9ULW6
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 INSYN1 Homo sapiens Q2T9L4
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 INSYN1 Homo sapiens Q2T9L4
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 BLOC1S2 Homo sapiens Q6QNY1
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 BLOC1S2 Homo sapiens Q6QNY1
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 GPRASP2 Homo sapiens Q96D09
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 GPRASP2 Homo sapiens Q96D09
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 GPRASP2 Homo sapiens Q96D09
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 THOC7 Homo sapiens Q6I9Y2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 THOC7 Homo sapiens Q6I9Y2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 MAGEA11 Homo sapiens P43364
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MAGEA11 Homo sapiens P43364
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CEP44 Homo sapiens Q9C0F1
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 CEP44 Homo sapiens Q9C0F1
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 CEP44 Homo sapiens Q9C0F1
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CCNDBP1 Homo sapiens O95273
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 CCNDBP1 Homo sapiens O95273
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CCDC197 Homo sapiens Q8NCU1
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 CCDC197 Homo sapiens Q8NCU1
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 CCDC197 Homo sapiens Q8NCU1
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 PDE4DIP Homo sapiens Q5VU43-2
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 PDE4DIP Homo sapiens Q5VU43-2
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 MRFAP1 Homo sapiens Q9Y605
Validated Y2H
32296183
Intra
CCDC146 Q8IYE0 MRFAP1 Homo sapiens Q9Y605
Y2H Array
32296183
Intra
CCDC146 Q8IYE0 MRFAP1 Homo sapiens Q9Y605
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
Intra
CCDC146 Q8IYE0 KRT86 Homo sapiens O43790
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Lymphogranuloma Venereum

  • Climatic Or Tropical Bubo

  • Durand-Nicolas-Favre Disease

  • Lymphogranuloma Inguinale

  • Poradenitis Inguinale

  • Strumous Bubo

  • Lgv
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02033 CCDC146 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CCDC146 VGNC VGNC:60464
Rattus norvegicus CCDC146 RGD RGD:1559535
Canis familiaris CCDC146 VGNC VGNC:38798
Bos taurus CCDC146 VGNC VGNC:26854
Macaca mulatta CCDC146 VGNC VGNC:70902
Mus musculus CCDC146 MGD MGI:1922422
Others CCDC146 NCBI