INSYN1 - inhibitory synaptic factor 1 Gene

Also Known as C15orf59

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 388135

Summary

Predicted to be involved in inhibitory postsynaptic potential. Predicted to be active in postsynaptic density. [provided by Alliance of Genome Resources, Jun 2026]
Biased expression in brain (RPKM 6.6), heart (RPKM 2.3) and 12 other tissues.

INSYN1 Products (5)

mRNA Protein Name
NM_001039614.3 NP_001034703.1 inhibitory synaptic factor 1 isoform 1
NM_001303254.2 NP_001290183.1 inhibitory synaptic factor 1 isoform 2
NM_001384351.1 NP_001371280.1 inhibitory synaptic factor 1 isoform 1
NM_001384352.1 NP_001371281.1 inhibitory synaptic factor 1 isoform 3
NM_001384353.1 NP_001371282.1 inhibitory synaptic factor 1 isoform 3
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

INSYN1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
INSYN1 Q2T9L4 BORCS6 Homo sapiens Q96GS4 33961781
Intra
INSYN1 Q2T9L4 BORCS6 Homo sapiens Q96GS4 32296183
Intra
INSYN1 Q2T9L4 CCDC146 Homo sapiens Q8IYE0 32296183
Intra
INSYN1 Q2T9L4 ABI2 Homo sapiens Q9NYB9-2 32296183
Intra
INSYN1 Q2T9L4 SNAPIN Homo sapiens O95295 33961781
Intra
INSYN1 Q2T9L4 MCRS1 Homo sapiens Q96EZ8 32296183
Intra
INSYN1 Q2T9L4 MCRS1 Homo sapiens Q96EZ8 33961781
Intra
INSYN1 Q2T9L4 BLOC1S6 Homo sapiens Q9UL45 32296183
Intra
INSYN1 Q2T9L4 BLOC1S6 Homo sapiens Q9UL45 32296183
Intra
INSYN1 Q2T9L4 WASHC3 Homo sapiens Q9Y3C0 32296183
Intra
INSYN1 Q2T9L4 WASHC3 Homo sapiens Q9Y3C0 33961781
Intra
INSYN1 Q2T9L4 PBX3 Homo sapiens Q96AL5 32296183
Intra
INSYN1 Q2T9L4 C19orf25 Homo sapiens Q9UFG5 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction