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54785

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8

Inhibitors & Agonists

1

Inhibitory Antibodies

2

Recombinant Proteins

4

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111253
    CYM-5478

    		LPL Receptor Neurological Disease
    CYM-5478 is a potent and highly selective S1P2 agonist with an EC50 of 119 nM in a TGFα-shedding assay. CYM-5478 protects neural-derived cell lines against Cisplatin toxicity .
    CYM-5478
  • HY-101716
    RP-54745
    1 Publications Verification

    		 Interleukin Related Inflammation/Immunology
    RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
    RP-54745
  • HY-P991555
    XmAb5485

    		TNF Receptor Apoptosis Cancer
    XmAb5485 is an Fc-engineered humanized anti-CD40 monoclonal antibody with high affinity to Fc-γ receptors. XmAb5485 induces potent antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) against tumor cells. XmAb5485 inhibits proliferation and induces apoptosis of tumor cells. XmAb5485 shows highly cytotoxic against lymphoma, leukemia and multiple myeloma cell lines as well as primary cancer cells .
    XmAb5485
  • HY-R01419A
    hsa-miR-4785 agomir

    		MicroRNA Cancer
    hsa-miR-4785 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-4785 agomir
    hsa-miR-4785 agomir
  • HY-R01419
    hsa-miR-4785 mimic

    		MicroRNA Cancer
    hsa-miR-4785 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-4785 mimic
    hsa-miR-4785 mimic
  • HY-101716R
    RP-54745 (Standard)

    		Reference Standards Interleukin Related Inflammation/Immunology
    RP-54745 (Standard) is the analytical standard of RP-54745 (HY-101716). This product is intended for research and analytical applications. RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
    RP-54745 (Standard)
  • HY-RI01419A
    hsa-miR-4785 antagomir

    		MicroRNA Cancer
    hsa-miR-4785 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-4785 antagomir
    hsa-miR-4785 antagomir
  • HY-RI01419
    hsa-miR-4785 inhibitor

    		MicroRNA Cancer
    hsa-miR-4785 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-4785 inhibitor
    hsa-miR-4785 inhibitor

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