MOS - MOS proto-oncogene, serine/threonine kinase Gene

Homo sapiens

Also known as MSV

Gene ID: 4342 | Gene type: protein coding

About MOS

Cytogenetic location: 8q12.1 Genomic coordinates (GRCh38): 8:56,112,942-56,113,982 (from NCBI)

This gene has 1 transcript (splice variant), 175 orthologues and 23 paralogues.

Summary

MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009]

MOS Products(1)

mRNA	Protein	Name
NM_005372.1	NP_005363.1	proto-oncogene serine/threonine-protein kinase mos

MOS Protein Structure

Pkinase

0
100
200
300
346 a.a.

Protein Preferred Names

Protein Names

proto-oncogene serine/threonine-protein kinase mos

c-mos

Related Diseases

Diseases

Alias

Sarcoma

Connective And Soft Tissue Neoplasm	Tumor Of Soft Tissue And Skeleton
Sarcomas	Sarcoma - Category

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08598	MOS Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MOS	VGNC	VGNC:68300
Bos taurus	MOS	VGNC	VGNC:31563
Rattus norvegicus	MOS	RGD	RGD:3103
Macaca mulatta	MOS	VGNC	VGNC:74911
Mus musculus	MOS	MGD	MGI:97052
Canis familiaris	MOS	VGNC	VGNC:43323
Macaca fascicularis	MOS	NCBI
Others	MOS	NCBI