MIPOL1 - mirror-image polydactyly 1 Gene

Homo sapiens

Also known as CCDC193

Gene ID: 145282 | Gene type: protein coding

About MIPOL1

Cytogenetic location: 14q13.3-q21.1 Genomic coordinates (GRCh38): 14:37,197,937-37,585,618 (from NCBI)

This gene has 30 transcripts (splice variants) and 177 orthologues. Broad expression in prostate (RPKM 1.7), testis (RPKM 0.6) and 20 other tissues.

Summary

This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]

MIPOL1 Products(14)

mRNA	Protein	Name
NM_001195296.2	NP_001182225.1	mirror-image polydactyly gene 1 protein isoform 1
NM_001195297.2	NP_001182226.1	mirror-image polydactyly gene 1 protein isoform 1
NM_001388067.1	NP_001374996.1	mirror-image polydactyly gene 1 protein isoform 1
NM_001388068.1	NP_001374997.1	mirror-image polydactyly gene 1 protein isoform 1
NM_001388069.1	NP_001374998.1	mirror-image polydactyly gene 1 protein isoform 2
NM_001388070.1	NP_001374999.1	mirror-image polydactyly gene 1 protein isoform 3
NM_001388071.1	NP_001375000.1	mirror-image polydactyly gene 1 protein isoform 3
NM_001388072.1	NP_001375001.1	mirror-image polydactyly gene 1 protein isoform 3
NM_001388073.1	NP_001375002.1	mirror-image polydactyly gene 1 protein isoform 4
NM_001388074.1	NP_001375003.1	mirror-image polydactyly gene 1 protein isoform 5
NM_001388075.1	NP_001375004.1	mirror-image polydactyly gene 1 protein isoform 5
NM_001388077.1	NP_001375006.1	mirror-image polydactyly gene 1 protein isoform 6
NM_001412440.1	NP_001399369.1	mirror-image polydactyly gene 1 protein isoform 7
NM_138731.7	NP_620059.1	mirror-image polydactyly gene 1 protein isoform 1

Protein Preferred Names

Protein Names

mirror-image polydactyly gene 1 protein

Related Diseases

Diseases

Alias

Polydactyly

Non-Syndromic Polydactyly	Polydactyly, Postaxial
Postaxial Polydactyly	Supernumerary Digit
Extra Digits	Hyperdactyly
Polydactylia	Polydactylism
Supernumerary Digits

Laurin-Sandrow Syndrome

Sandrow Syndrome	Tetramelic Mirror-Image Polydactyly
Mirror-Image Polydactyly	Mirror Hands And Feet With Nasal Defects
Tmip	LSS
Mip	Mirror Hands And Feets-Nasal Defects Syndrome
Fibula And Ulna, Duplication Of, With Absence Of Tibia And Radius	Miccor Hands And Feet With Nasal Defects
Mipduplication Of Fibuland Ulna With Absence Of Tibia And Radius	Fibula Ulna Duplication Tibia Radius Absence
Laurin Sandrow Syndrome	Duplication Of Fibula And Ulna With Absence Of Tibia And Radius
Segmental Laurin-Sandrow Syndrome	Laurin-Sandrow Syndrome, Segmental

Bronchus Adenoma

Bronchial Adenoma

Adenoma Of The Bronchus

Acute Laryngitis

Acute Laryngitis Nos	Laryngeal Inflammation
Laryngitis Nos	Larynx Inflammation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08462	MIPOL1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	MIPOL1	VGNC	VGNC:106823
Canis familiaris	MIPOL1	VGNC	VGNC:43243
Felis catus	MIPOL1	VGNC	VGNC:80911
Rattus norvegicus	MIPOL1	RGD	RGD:6504372
Mus musculus	MIPOL1	MGD	MGI:1920740
Macaca mulatta	MIPOL1	VGNC	VGNC:74801

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