UTP25 - UTP25 small subunit processome component Gene

Also Known as DEF; DIEXF; C1orf107; DJ434O14.5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27042

About UTP25

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:209,827,972-209,857,565 (from NCBI)

This gene has 2 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in ovary (RPKM 3.8), thyroid (RPKM 2.8) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in several processes, including protein catabolic process; protein destabilization; and protein localization to nucleolus. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

UTP25 Products (1)

mRNA Protein Name
NM_014388.7 NP_055203.4 U3 small nucleolar RNA-associated protein 25 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23357851 GOA
Biological Process GO Annotation Evidence References Source
involved in embryonic organ development IMP
IMP: Inferred from mutant phenotype
27657329 GOA
involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
23357851 GOA
involved in protein destabilization IMP
IMP: Inferred from mutant phenotype
23357851 GOA
involved in protein localization to nucleolus IDA
IDA: Inferred from direct assay
27657329 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
23357851 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UTP25 Protein Structure

UTP25

UTP25: Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 (316 - 751)

  • 0
  • 200
  • 400
  • 600
  • 756 a.a.
Protein Preferred Names Protein Names

U3 small nucleolar RNA-associated protein 25 homolog

  • UTP25 small subunit processor component

UTP25 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
UTP25 Q68CQ4 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
25416956
Intra
UTP25 Q68CQ4 MAGEA11 Homo sapiens P43364-2
Validated Y2H
25416956
Intra
UTP25 Q68CQ4 MAGEA11 Homo sapiens P43364-2
Y2H Array
25416956
Intra
UTP25 Q68CQ4 ZBTB10 Homo sapiens Q96DT7-3
Y2H Prey Pooling
32296183
Intra
UTP25 Q68CQ4 ZBTB10 Homo sapiens Q96DT7-3
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 ZBTB10 Homo sapiens Q96DT7-3
Y2H Array
32296183
Intra
UTP25 Q68CQ4 RUFY1 Homo sapiens Q96T51-2
Y2H Prey Pooling
32296183
Intra
UTP25 Q68CQ4 RUFY1 Homo sapiens Q96T51-2
Y2H Array
31515488
Intra
UTP25 Q68CQ4 RUFY1 Homo sapiens Q96T51-2
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 RUFY1 Homo sapiens Q96T51-2
Y2H Array
32296183
Intra
UTP25 Q68CQ4 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
UTP25 Q68CQ4 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
UTP25 Q68CQ4 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
25416956
Intra
UTP25 Q68CQ4 MIPOL1 Homo sapiens Q8TD10
Y2H Array
25416956
Intra
UTP25 Q68CQ4 AP2M1 Homo sapiens Q96CW1
Y2H Prey Pooling
32296183
Intra
UTP25 Q68CQ4 AP2M1 Homo sapiens Q96CW1
Y2H Array
32296183
Intra
UTP25 Q68CQ4 AP2M1 Homo sapiens Q96CW1
Anti Tag CoIP
33961781
Intra
UTP25 Q68CQ4 AP2M1 Homo sapiens Q96CW1
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 RUFY1 Homo sapiens Q96T51
Y2H Prey Pooling
25416956
Intra
UTP25 Q68CQ4 RUFY1 Homo sapiens Q96T51
Y2H Array
25416956
Intra
UTP25 Q68CQ4 TRIM62 Homo sapiens Q9BVG3
Y2H Prey Pooling
32296183
Intra
UTP25 Q68CQ4 TRIM62 Homo sapiens Q9BVG3
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 TRIM62 Homo sapiens Q9BVG3
Y2H Array
32296183
Intra
UTP25 Q68CQ4 TRIM9 Homo sapiens Q9C026
Y2H Array
32296183
Intra
UTP25 Q68CQ4 TRIM9 Homo sapiens Q9C026
Y2H Prey Pooling
32296183
Intra
UTP25 Q68CQ4 TRIM9 Homo sapiens Q9C026
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra
UTP25 Q68CQ4 CEP70 Homo sapiens Q8NHQ1
Y2H Array
25416956
Intra
UTP25 Q68CQ4 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
UTP25 Q68CQ4 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
25416956
Intra
UTP25 Q68CQ4 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15578 UTP25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris UTP25 VGNC VGNC:55764
Felis catus UTP25 VGNC VGNC:66905
Mus musculus UTP25 MGD MGI:2138080
Rattus norvegicus UTP25 RGD RGD:1359148
Bos taurus UTP25 VGNC VGNC:54509
Macaca mulatta UTP25 VGNC VGNC:79711
Others UTP25 NCBI