2. Gene
  3. CDK18 - cyclin dependent kinase 18 Gene

CDK18 - cyclin dependent kinase 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PCTK3; PCTAIRE; PCTAIRE3

Gene ID: 5129 | Gene type: protein coding

About CDK18

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,504,669-205,532,790 (from NCBI)

This gene has 23 transcripts (splice variants), 198 orthologues and 26 paralogues. Broad expression in heart (RPKM 26.3), brain (RPKM 20.4) and 20 other tissues.

Summary

Predicted to enable ATP binding activity; cyclin-dependent protein serine/threonine kinase activity; and protein serine kinase activity. Predicted to be involved in protein phosphorylation and regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CDK18 Products(3)

mRNA Protein Name
NM_002596.4 NP_002587.2 cyclin-dependent kinase 18 isoform b
NM_212502.3 NP_997667.1 cyclin-dependent kinase 18 isoform b
NM_212503.3 NP_997668.1 cyclin-dependent kinase 18 isoform a

CDK18 Protein Structure

Pkinase

Pkinase: Protein kinase domain (174 - 455)

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  • 504 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 18

PCTAIRE protein kinase 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02370 CDK18 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CDK18 VGNC VGNC:68737
Rattus norvegicus CDK18 RGD RGD:1309523
Bos taurus CDK18 VGNC VGNC:27121
Canis familiaris CDK18 VGNC VGNC:39049
Mus musculus CDK18 MGD MGI:97518
Macaca mulatta CDK18 VGNC VGNC:71162
Others CDK18 NCBI