CCND3 - cyclin D3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 896

About CCND3

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,934,933-42,048,894 (from NCBI)

This gene has 23 transcripts (splice variants), 244 orthologues, 18 paralogues and is associated with 73 phenotypes. Broad expression in bone marrow (RPKM 45.2), lymph node (RPKM 40.1) and 24 other tissues.

Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into Mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

CCND3 Products (6)

mRNA Protein Name
NM_001136017.3 NP_001129489.1 G1/S-specific cyclin-D3 isoform 1
NM_001136125.3 NP_001129597.1 G1/S-specific cyclin-D3 isoform 3
NM_001136126.3 NP_001129598.1 G1/S-specific cyclin-D3 isoform 4
NM_001287427.2 NP_001274356.1 G1/S-specific cyclin-D3 isoform 5
NM_001287434.2 NP_001274363.1 G1/S-specific cyclin-D3 isoform 4
NM_001760.5 NP_001751.1 G1/S-specific cyclin-D3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cyclin-dependent protein serine/threonine kinase activator activity IDA
IDA: Inferred from direct assay
8114739 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9106657 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
8114739 GOA
Biological Process GO Annotation Evidence References Source
involved in G1/S transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
8114739 GOA
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
8114739 GOA
involved in positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
8114739 GOA
Cellular Component GO Annotation Evidence References Source
part of cyclin D3-CDK4 complex IPI
IPI: Inferred from physical interaction
19237555 GOA
part of cyclin D3-CDK6 complex IPI
IPI: Inferred from physical interaction
8114739 GOA
part of cyclin-dependent protein kinase holoenzyme complex IDA
IDA: Inferred from direct assay
8114739 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCND3 Protein Structure

Cyclin_N

Cyclin_N: Cyclin, N-terminal domain (27 - 152)

Cyclin_C

Cyclin_C: Cyclin, C-terminal domain (156 - 260)

  • 0
  • 100
  • 200
  • 292 a.a.
Protein Preferred Names Protein Names

G1/S-specific cyclin-D3

  • D3-type cyclin

CCND3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCND3 P30281 CDK5 Homo sapiens Q00535
Anti Tag CoIP
34591612
Intra
CCND3 P30281 CDK5 Homo sapiens Q00535
Validated Y2H
32296183
Intra
CCND3 P30281 CDK5 Homo sapiens Q00535
Anti Tag CoIP
33961781
Intra
CCND3 P30281 CDK5 Homo sapiens Q00535
Anti Tag CoIP
28514442
Intra
CCND3 P30281 CDK14 Homo sapiens O94921
Anti Tag CoIP
17517622
Intra
CCND3 P30281 CCDC13 Homo sapiens Q8IYE1
Validated Y2H
32296183
Intra
CCND3 P30281 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra
CCND3 P30281 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra
CCND3 P30281 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
25416956
Intra
CCND3 P30281 CDK16 Homo sapiens Q00536-3
Validated Y2H
32296183
Intra
CCND3 P30281 CDK3 Homo sapiens Q00526
Validated Y2H
32296183
Intra
CCND3 P30281 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
CCND3 P30281 POLR3GL Homo sapiens Q9BT43
Validated Y2H
32296183
Intra
CCND3 P30281 POLR3GL Homo sapiens Q9BT43
Y2H Array
25416956
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Y2H Pooling
16189514
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Y2H
21516116
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Y2H Array
31515488
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Anti Tag CoIP
34591612
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Y2H Prey Pooling
25416956
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Validated Y2H
25416956
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Anti Tag CoIP
33961781
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
BFG-2H
27107012
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Anti Tag CoIP
28514442
Intra
CCND3 P30281 CDK4 Homo sapiens P11802
Anti Bait CoIP
11896535
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
MAPPIT
32296183
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Lumier
29997244
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Anti Tag CoIP
33961781
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Anti Tag CoIP
34591612
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Complementation
32296183
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
BRET
29997244
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Anti Tag CoIP
28514442
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Lumier
32814053
Intra
CCND3 P30281 CDK6 Homo sapiens Q00534
Validated Y2H
32296183
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Anti Tag CoIP
34591612
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Y2H Pooling
16189514
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Validated Y2H
32296183
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Y2H Array
25416956
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Anti Tag CoIP
33961781
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Anti Tag CoIP
28514442
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
MAPPIT
25416956
Intra
CCND3 P30281 CDKN1A Homo sapiens P38936
Y2H Array
31515488
Intra
CCND3 P30281 CDKN1B Homo sapiens P46527
Anti Tag CoIP
34591612
Intra
CCND3 P30281 CDKN1B Homo sapiens P46527
Anti Tag CoIP
28514442
Intra
CCND3 P30281 CDKN1B Homo sapiens P46527
Anti Tag CoIP
33961781
Intra
CCND3 P30281 CDKN1B Homo sapiens P46527
Y2H Pooling
16189514
Intra
CCND3 P30281 C14orf119 Homo sapiens Q9NWQ9
Validated Y2H
32296183
Intra
CCND3 P30281 MNS1 Homo sapiens Q8NEH6
Validated Y2H
32296183
Intra
CCND3 P30281 CDKN2D Homo sapiens P55273
Validated Y2H
32296183
Intra
CCND3 P30281 CDK18 Homo sapiens Q07002
Validated Y2H
32296183
Intra
CCND3 P30281 CDK18 Homo sapiens Q07002
Y2H Prey Pooling
32296183
Cross
CCND3 P30281 AKAP8 Canis familiaris Q5VK71
Anti Bait CoIP
14641107
Cross
CCND3 P30281 AKAP8 Canis familiaris Q5VK71
Y2H
14641107
Cross
CCND3 P30281 ICP0 Human herpesvirus 1 P08393
Pull Down
9311810
Cross
CCND3 P30281 ICP0 Human herpesvirus 1 P08393
Y2H
9311810
Cross
CCND3 P30281 ICP0 Human herpesvirus 1 P08393
IF
9311810
Cross: Cross-species interaction Intra: Intraspecies interaction

CCND3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P80099 Cyclin D3/CCND3 Antibody (YA484) WB, ICC/IF Human, Mouse
HY-P81456 Cyclin D3/CCND3 Antibody (YA1201) IHC-P Human
HY-P81456A Cyclin D3/CCND3 Antibody (YA1201)(PBS only) IHC-P Human
HY-P85115 Cyclin D3/CCND3 Antibody (YA4807) WB, ELISA Human, Mouse

Related Diseases

Diseases Alias
Retinoblastoma

  • RB

  • Trilateral Retinoblastoma

  • RB1

  • Retinoblastoma, Trilateral

  • Neuroblastoma Of Retina

  • Rb - Retinoblastoma

  • Eye Cancer, Retinoblastoma

  • Retinal Cancer

  • Retinal Tumor

  • Glioma, Retinal

  • Non-Hereditary Retinoblastoma

  • Childhood Cancer Retinoblastoma

  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms
Plasma Cell Leukemia

  • Plasma Cell Leukaemia

  • Leukemia, Plasma Cell

  • Plasmacytic Leukaemia

  • Plasmacytic Leukemia

  • Pcl

  • Plasma Cell Leukaemia, Nos

  • Leukemic Plasma Cell

  • Plasma Cell Leukaemia Without Mention Of Remission
Follicular Lymphoma

  • Lymphoma, Follicular

  • Lymphoma Follicular

  • Brill-Symmers' Disease

  • Large Cell Follicular Non-Hodgkin Lymphoma

  • Diffuse Follicle Centre Lymphoma

  • Diffuse Follicular Lymphoma Nos

  • Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

  • Follicular Large Cell Cleaved Or Noncleaved Lymphoma

  • Large Cell Follicular Noncleaved Lymphoma

  • Follicular Lymphoma With Or Without Diffuse Areas

  • Histiocytic Follicular Lymphoma

  • Histiocytic Nodular Lymphoma

  • Histiocytic Nodular Malignant Lymphoma

  • Large Cell Follicular Lymphoma

  • Large Cell Noncleaved Follicular Lymphoma

  • Large Cell Noncleaved Follicular Malignant Lymphoma

  • Nodular Reticulum Cell Sarcoma

  • Noncleaved Follicular Lymphoma
B-Cell Lymphoma

  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos
Gliosarcoma

  • Glioblastoma With Sarcomatous Component

  • Sarcomatous Glioblastoma
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Laryngeal Squamous Cell Carcinoma

  • Epidermoid Carcinoma Of The Larynx

  • Squamous Cell Carcinoma Of Larynx

  • Squamous Cell Carcinoma Of The Larynx

  • Squamous Cell Carcinoma Of Head And Neck
Reticulosarcoma

  • Histiocytic Lymphoma

  • Large-Cell Lymphomas

  • Lymphoma, Large-Cell

  • Lymphoma Large Cell

  • Diffuse Large B-Cell Lymphoma

  • Histiocytic Sarcoma
Pancreatic Adenocarcinoma

  • Adenocarcinoma Of The Pancreas

  • Adenocarcinoma Of Pancreas

  • Pancreas Adenocarcinoma

  • Malignant Exocrine Neoplasm

  • Primary Pancreatic Adenocarcinoma

  • Adenocarcinoma Of Islet Cell Of Pancreas

  • Islet Cell Adenocarcinoma Of Unspecified Site

  • Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Myeloma, Multiple

  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]
Ewing Sarcoma

  • Neuroepithelioma

  • Ewing'S Tumor

  • Primitive Neuroectodermal Tumor

  • Ewings Sarcoma

  • Ewing'S Sarcoma

  • Peripheral Neuroepithelioma

  • ES

  • Ewings Sarcoma-Primitive Neuroectodermal Tumor

  • Localized Peripheral Primitive Neuroectodermal Tumor

  • Peripheral Primitive Neuroectodermal Tumor

  • Ewing Tumor

  • Sarcoma, Ewing'S

  • Ewing Family Of Tumors

  • Extraosseous Ewing Tumor

  • Askin Tumor

  • Ewing'S Family Localized Tumor

  • Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

  • Localized Ewing Sarcoma

  • Localized Ewing'S Sarcoma

  • Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

  • Localized Ewing'S Tumor

  • Pnet Of Thoracopulmonary Region

  • Tumor Of The Ewing Family

  • Skeletal Ewing Sarcoma

  • Osseous Ewing Sarcoma

  • Ppnet

  • Peripheral Pnet

  • Extraskeletal Ewing Sarcoma

  • Eoe

  • Extraosseous Ewing Sarcoma

  • Extraskeletal Ewing Tumor

  • Esft

  • Ewing Sarcoma Family Of Tumors

  • Pne

  • Pnet

  • Pnet Of The Chest Wall

  • Sarcoma, Ewing

  • Neuroectodermal Tumors, Primitive, Peripheral

  • Neuroectodermal Tumor, Primitive

  • Disorder Of Eye

  • Askin'S Tumor

  • Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

  • Neuroepithelioma, Peripheral
Lymphoma, Non-Hodgkin, Familial

  • Non-Hodgkin Lymphoma

  • Lymphoma, Non-Hodgkin

  • NHL

  • Lymphoma, Non-Hodgkin, Somatic

  • Lymphoma, Follicular, Somatic

  • Familial Non-Hodgkin Lymphoma

  • Lymphoma Non-Hodgkins

  • Follicular Lymphoma, Somatic

  • Lymphosarcoma

  • Non-Hodgkins Lymphoma
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Glioblastoma

  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma
Sarcomatoid Transitional Cell Carcinoma

  • Transitional Cell Carcinoma, Sarcomatoid

  • Transitional Spindle Cell Carcinoma

  • Transitional Cell Carcinoma, Spindle Cell
Burkitt Lymphoma

  • Burkitt'S Lymphoma

  • BL

  • Burkitt Lymphoma, Somatic

  • Burkitt Lymphoma/Leukaemia

  • Burkitt'S Tumor

  • Burkitt'S Tumor Or Lymphoma

  • Malignant Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma

  • Burkitt Tumor

  • Burkitts Lymphoma

  • Lymphoma, Small Noncleaved-Cell

  • Burkitt Tumour

  • Diffuse Small Noncleaved Malignant Burkitt Lymphoma

  • Malignant Burkitt Lymphoma

  • “Burkitt-Like” Lymphoma

  • Undifferentiated Burkitt Lymphoma

  • Small Noncleaved Cell Burkitt Lymphoma
Embryonal Rhabdomyosarcoma

  • Rhabdomyosarcoma, Embryonal

  • Rhabdomyosarcoma Embryonal

  • Botryoid Rhabdomyosarcoma

  • Erms

  • Spindle Cell Rhabdomyosarcomas
Monoclonal Gammopathy Of Uncertain Significance

  • Monoclonal Gammopathy Of Undetermined Significance

  • Mgus

  • Mgus - [Monoclonal Gammopathy Of Undetermined Significance]

  • Monoclonal Gammopathy Nos

  • Iga Gammopathy

  • Monoclonal Gammoglobulinopathy
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit

  • Hgbl-Dh/Th

  • High Grade B-Cell Lymphoma With Myc And Bcl2 Or Bcl6 Rearrangements

  • High Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement
Bladder Cancer

  • Urinary Bladder Cancer

  • Bladder Carcinoma

  • Urinary Bladder Carcinoma

  • Bladder Neoplasm

  • Bladder Tumor

  • Cancer, Bladder

  • Malignant Neoplasm Of Urinary Bladder

  • Carcinoma Of Bladder

  • Bladder Cancer, Somatic

  • Tumor Of The Bladder

  • Carcinoma Of Urinary Bladder

  • Bladder Carcinoma Urinary

  • Cancer Of The Urinary Bladder

  • Cancer, Urinary Bladder

  • Malignant Bladder Neoplasm

  • Malignant Bladder Tumor

  • Neoplasm Of The Bladder

  • Neoplasm Of The Urinary Bladder

  • Tumor Of The Urinary Bladder

  • Urinary Bladder Neoplasm

  • BLC

  • Urothelial Carcinoma Of The Bladder

  • Bladder Tumors

  • Urinary Bladder Neoplasms

  • Bladder Cancer Nos

  • Vesical Cancer Nos

  • Malignant Neoplasm Of Bladder, Part Unspecified

  • Malignant Tumour Of Urinary Bladder

  • Primary Malignant Neoplasm Of Bladder
Leukemia, Chronic Lymphocytic

  • Chronic Lymphocytic Leukemia

  • B-Cell Chronic Lymphocytic Leukemia

  • CLL

  • B-Cell Chronic Lymphoid Leukemia

  • Chronic Lymphatic Leukemia

  • Chronic Lymphocytic Leukaemia

  • Lymphoplasmacytic Leukemia

  • Small Lymphocytic Lymphoma

  • Leukemia, Chronic Lymphatic

  • B-Cell Chronic Lymphocytic Leukaemia

  • Chronic Lymphatic Leukaemia

  • Lymphoplasmacytic Leukaemia

  • B Cell Chronic Lymphocytic Leukemia

  • Chronic B-Cell Lymphocytic Leukemia

  • Leukemia, Lymphocytic, Chronic

  • B-Cll

  • Chronic Lymphoid Leukemia

  • Leukemia Lymphocytic Chronic

  • Lymphoma Small Lymphocytic

  • Leukemia, Lymphocytic, Chronic, B-Cell
T-Cell Acute Lymphoblastic Leukemia

  • T-Cell Leukemia

  • Acute T Cell Leukemia

  • Precursor T Lymphoblastic Leukemia

  • Precursor T-Lymphoblastic Lymphoma/Leukemia

  • T Acute Lymphoblastic Leukemia

  • T-Cell Acute Lymphocytic Leukaemia

  • T-Cell Lymphoblastic Leukemia/Lymphoma

  • Leukemia T-Cell

  • Leukemia, T-Cell

  • Leukemia, Acute, Lymphoblastic, T-Cell

  • Leukemia, T-Cell Acute Lymphoblastic

  • Leukemia, Acute T-Cell

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

  • Precursor T-Cell Lymphoblastic Lymphoma

  • Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Blood Protein Disease

  • Blood Protein Disorders

  • Blood Protein Disorder
Retinal Cancer

  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms

  • Malignant Retinal Neoplasm

  • Malignant Tumor Of Retina

  • Neoplasm Of Retina

  • Retinal Tumor

  • Retinal Neoplasm

  • Cancer Of The Retina

  • Malignant Retinal Tumour

  • Malignant Tumour Of Retina

  • Primary Malignant Neoplasm Of Retina
Mantle Cell Lymphoma

  • Lymphoma, Mantle Cell

  • Lcm

  • Mcl

  • Mantle Zone Lymphoma

  • Lymphoma Mantle-Cell

  • Lymphoma, Mantle-Cell

  • Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

  • Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

  • Diffuse Small Cleaved-Cell Lymphoma

  • Diffuse Small Cleaved Cell Malignant Lymphoma

  • Small Cleaved Cell Non-Hodgkin Lymphoma

  • Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

  • Malignant Lymphomatous Polyposis

  • Malignant Small Cell, Noncleaved, Diffuse Lymphoma

  • Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

  • Cleaved Cell Lymphoma

  • Small Cell Mantle Cell Lymphoma

  • Small Cleaved Cell Malignant Lymphoma
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Leukemia, Acute Lymphoblastic

  • Acute Lymphoblastic Leukemia

  • ALL

  • Acute Lymphocytic Leukemia

  • Leukemia, Acute Lymphocytic, Susceptibility To, 1

  • Acute Lymphoblastic Leukaemia

  • Precursor Lymphoblastic Lymphoma/Leukemia

  • Precursor Lymphoid Neoplasm

  • Leukemia, Acute Lymphoblastic, Susceptibility To

  • B-Cell Acute Lymphoblastic Leukemia

  • Leukemia, Acute Lymphocytic 1

  • Acute Lymphocytic Leukaemia

  • Acute Lymphoblastic Leukemia/Lymphoma

  • All1

  • Childhood Acute Lymphoblastic Leukemia

  • Leukemia Acute Lymphoblastic 1

  • Leukemia Acute Lymphoblastic B-Hyperdiploid

  • Leukemia Acute Lymphocytic

  • Leukemia Acute Lymphocytic 1

  • Leukemia B-Cell Acute Lymphoblastic

  • Leukemia T-Cell Acute Lymphoblastic

  • Leukemia, Acute Lymphoblastic, 3

  • ALL3

  • Lymphoblastic Leukemia Acute

  • Leukemia, Acute, Lymphoblastic

  • Precursor Cell Lymphoblastic Leukemia Lymphoma

  • Leukemia, Lymphocytic, Acute, L1

  • Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Eye Disease

  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-R04612 4o8G-miR-592 / Unkown
HY-RS02125 CCND3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19992 Ccnd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26496 Ccnd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CCND3 VGNC VGNC:26964
Felis catus CCND3 VGNC VGNC:102395
Rattus norvegicus CCND3 RGD RGD:2293
Macaca mulatta CCND3 VGNC VGNC:70724
Mus musculus CCND3 MGD MGI:88315
Canis familiaris CCND3 VGNC VGNC:54284
Others CCND3 NCBI