MNS1 - meiosis specific nuclear structural 1 Gene

Homo sapiens

Also known as HTX9; SPATA40

Gene ID: 55329 | Gene type: protein coding

About MNS1

Cytogenetic location: 15q21.3 Genomic coordinates (GRCh38): 15:56,428,724-56,465,137 (from NCBI)

This gene has 3 transcripts (splice variants), 207 orthologues and is associated with 1 phenotype. Biased expression in testis (RPKM 28.7), kidney (RPKM 5.6) and 13 other tissues.

Summary

This gene encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuclear morphology during meiosis. [provided by RefSeq, Oct 2008]

MNS1 Products(1)

mRNA	Protein	Name
NM_018365.4	NP_060835.1	meiosis-specific nuclear structural protein 1

MNS1 Protein Structure

TPH

0
100
200
300
400
495 a.a.

Protein Preferred Names

Protein Names

meiosis-specific nuclear structural protein 1

spermatogenesis associated 40

Related Diseases

Diseases

Alias

Heterotaxy, Visceral, 9, Autosomal, With Male Infertility

HTX9

Situs Inversus

Situs Inversus Viscerum	Laterality Sequence
Complete Transposition	Siv

Dextrocardia With Situs Inversus

Situs Inversus Totalis	Complete Situs Inversus
Complete Situs Inversus Viscerum	Situs Inversus

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Osteogenesis Imperfecta, Type Xiv

Osteogenesis Imperfecta Type 14	OI14
Osteogenesis Imperfecta Type Xiv	Oi, Type Xiv
Osteogenesis Imperfecta 14	Oi Type Xiv
Oi-Xiv

Visceral Heterotaxy

Situs Ambiguus	Heterotaxia
Heterotaxy Syndrome	Heterotaxy
Lateralization Defect	Situs Ambiguous
Left Isomerism	Htx
Ivemark Syndrome	Right Isomerism
Situs Ambiguus Viscerum	Incomplete Situs Inversus
Partial Situs Inversus	Heterotaxy, Visceral
Asplenia Syndrome	Bilateral Left-Sidedness
Polysplenia Syndrome	Moller Syndrome

Infertility

Borderline Glaucoma

Preglaucoma

Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

Polycystic Kidney Disease 2	PKD2
Polycystic Kidney Disease, Adult, Type Ii	Apkd2
Polycystic Kidney Disease, Type 2	Adpkd2
Adult Polycystic Kidney Disease Type 2	Autosomal Dominant Polycystic Kidney Disease 2
Pkd-2	Polycystic Kidney Disease Adult Type Ii
Polycystic Kidney Type 2 Autosomal Dominant Disease	Kidney Disease, Polycystic, Type 2

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08569	MNS1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MNS1	RGD	RGD:1549718
Macaca mulatta	MNS1	VGNC	VGNC:74861
Canis familiaris	MNS1	VGNC	VGNC:43297
Mus musculus	MNS1	MGD	MGI:107933
Bos taurus	MNS1	VGNC	VGNC:31539
Felis catus	MNS1	VGNC	VGNC:104496