SNX32 - sorting nexin 32 Gene

Also Known as SNX6B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 254122

About SNX32

This gene has 9 transcripts (splice variants), 154 orthologues and 15 paralogues. Biased expression in brain (RPKM 2.1), testis (RPKM 1.0) and 7 other tissues.

Summary

Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be active in endosome. [provided by Alliance of Genome Resources, Apr 2022]

SNX32 Products (1)

mRNA Protein Name
NM_152760.3 NP_689973.2 sorting nexin-32

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21516116 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNX32 Protein Structure

PX

PX: PX domain (24 - 163)

Vps5

Vps5: Vps5 C terminal like (186 - 330)

  • 0
  • 100
  • 200
  • 300
  • 403 a.a.
Protein Preferred Names Protein Names

sorting nexin-32

  • sorting nexin-6B

SNX32 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SNX32 Q86XE0 SNX2 Homo sapiens O60749
Y2H Array
32296183
Intra
SNX32 Q86XE0 SNX2 Homo sapiens O60749
Y2H Prey Pooling
32296183
Intra
SNX32 Q86XE0 SNX2 Homo sapiens O60749
Anti Tag CoIP
33961781
Intra
SNX32 Q86XE0 SNX2 Homo sapiens O60749
Anti Tag CoIP
28514442
Intra
SNX32 Q86XE0 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
SNX32 Q86XE0 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
SNX32 Q86XE0 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
SNX32 Q86XE0 SPANXB1 Homo sapiens Q9NS25
Validated Y2H
32296183
Intra
SNX32 Q86XE0 SNX1 Homo sapiens Q13596
Anti Tag CoIP
28514442
Intra
SNX32 Q86XE0 SNX1 Homo sapiens Q13596
Y2H Prey Pooling
32296183
Intra
SNX32 Q86XE0 SNX1 Homo sapiens Q13596
Y2H Array
32296183
Intra
SNX32 Q86XE0 SNX1 Homo sapiens Q13596
Anti Tag CoIP
33961781
Intra
SNX32 Q86XE0 MNS1 Homo sapiens Q8NEH6
Validated Y2H
32296183
Intra
SNX32 Q86XE0 NME7 Homo sapiens Q9Y5B8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Amyotrophic Lateral Sclerosis 7

  • ALS7

  • Amyotrophic Lateral Sclerosis Type 7
Retinitis Pigmentosa 39

  • RP39

  • Retinitis Pigmentosa, Type 39
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13541 SNX32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SNX32 VGNC VGNC:65555
Canis familiaris SNX32 VGNC VGNC:46639
Rattus norvegicus SNX32 RGD RGD:1560591
Macaca mulatta SNX32 VGNC VGNC:77777
Mus musculus SNX32 MGD MGI:2444704
Others SNX32 NCBI