2. Gene
  3. CDK14 - cyclin dependent kinase 14 Gene

CDK14 - cyclin dependent kinase 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PFTK1; PFTAIRE1

Gene ID: 5218 | Gene type: protein coding

About CDK14

Cytogenetic location: 7q21.13 Genomic coordinates (GRCh38): 7:90,596,321-91,210,590 (from NCBI)

This gene has 15 transcripts (splice variants), 201 orthologues and 26 paralogues. Ubiquitous expression in brain (RPKM 6.5), kidney (RPKM 3.1) and 24 other tissues.

Summary

PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]

CDK14 Products(4)

mRNA Protein Name
NM_001287136.1 NP_001274065.1 cyclin-dependent kinase 14 isoform c
NM_001287137.1 NP_001274066.1 cyclin-dependent kinase 14 isoform d
NM_001287135.2 NP_001274064.1 cyclin-dependent kinase 14 isoform a
NM_012395.3 NP_036527.1 cyclin-dependent kinase 14 isoform b

CDK14 Protein Structure

Pkinase

Pkinase: Protein kinase domain (135 - 419)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 469 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 14

PFTAIRE protein kinase 1

cell division protein kinase 14

serine/threonine-protein kinase PFTAIRE-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-127104 FMF-04-159-2 Inhibitor 98.92% Unkown
HY-160213 JA397 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CDK14 VGNC VGNC:106680
Canis familiaris CDK14 VGNC VGNC:39046
Rattus norvegicus CDK14 RGD RGD:1305544
Macaca mulatta CDK14 VGNC VGNC:71164
Mus musculus CDK14 MGD MGI:894318
Felis catus CDK14 VGNC VGNC:68810