1. PROTAC
  2. PROTACs
  3. SB1-G-187

SB1-G-187 

Cat. No.: HY-137342
Handling Instructions

SB1-G-187, a PROTAC, is a multi-kinase degrader.

For research use only. We do not sell to patients.

SB1-G-187 Chemical Structure

SB1-G-187 Chemical Structure

Size Stock
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500 mg   Get quote  

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Description

SB1-G-187, a PROTAC, is a multi-kinase degrader[1].

Molecular Weight

1022.03

Formula

C52H54F3N9O10

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (97.84 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9784 mL 4.8922 mL 9.7844 mL
5 mM 0.1957 mL 0.9784 mL 1.9569 mL
10 mM 0.0978 mL 0.4892 mL 0.9784 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 5 mg/mL (4.89 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (4.89 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
SB1-G-187
Cat. No.:
HY-137342
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