HAUS1 - HAUS augmin like complex subunit 1 Gene

Homo sapiens

Also known as HEIC; CCDC5; HEI-C; HsT1461

Gene ID: 115106 | Gene type: protein coding

About HAUS1

Cytogenetic location: 18q21.1 Genomic coordinates (GRCh38): 18:46,104,385-46,128,333 (from NCBI)

This gene has 12 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in lymph node (RPKM 14.6), bone marrow (RPKM 12.1) and 25 other tissues.

Summary

HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

HAUS1 Products(1)

mRNA	Protein	Name
NM_138443.4	NP_612452.1	HAUS augmin-like complex subunit 1

Protein Preferred Names

Protein Names

HAUS augmin-like complex subunit 1

coiled-coil domain containing 5 (spindle associated)

Related Diseases

Diseases

Alias

Aleukemic Leukemia Cutis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06013	HAUS1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	HAUS1	MGD	MGI:2385076
Rattus norvegicus	HAUS1	RGD	RGD:619909
Canis familiaris	HAUS1	VGNC	VGNC:41602
Bos taurus	HAUS1	VGNC	VGNC:29757
Felis catus	HAUS1	VGNC	VGNC:62755
Macaca mulatta	HAUS1	VGNC	VGNC:103824

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