CAGE1 - cancer antigen 1 Gene

Also Known as CT3; CT95; CTAG3; bA69L16.7

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 285782

About CAGE1

Cytogenetic location: 6p24.3 Genomic coordinates (GRCh38): 6:7,326,659-7,389,742 (from NCBI)

This gene has 9 transcripts (splice variants) and 96 orthologues. Restricted expression toward testis (RPKM 5.0).

CAGE1 Products (3)

mRNA	Protein	Name
NM_001170692.2	NP_001164163.1	cancer-associated gene 1 protein isoform 1
NM_001170693.2	NP_001164164.1	cancer-associated gene 1 protein isoform 2
NM_205864.3	NP_995586.1	cancer-associated gene 1 protein isoform 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CAGE1 Protein Structure

CAGE1

0
200
400
600
777 a.a.

Protein Preferred Names	Protein Names
cancer-associated gene 1 protein	cancer/testis antigen 3

CAGE1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CAGE1	Q8TC20	TBC1D23	Homo sapiens	Q9NUY8-2	Validated Y2H	25416956
Intra	CAGE1	Q8TC20	MPPED2	Homo sapiens	Q15777	Validated Y2H	25416956
Intra	CAGE1	Q8TC20	HAUS1	Homo sapiens	Q96CS2	Y2H Array	25416956
Intra	CAGE1	Q8TC20	HAUS1	Homo sapiens	Q96CS2	Y2H Prey Pooling	25416956
Intra	CAGE1	Q8TC20	TBC1D23	Homo sapiens	Q9NUY8	Y2H Array	25416956
Intra	CAGE1	Q8TC20	TPM1	Homo sapiens	P09493	Y2H Array	25416956
Intra	CAGE1	Q8TC20	MRFAP1L1	Homo sapiens	Q96HT8	Validated Y2H	25416956
Intra	CAGE1	Q8TC20	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Intraocular Retinoblastoma	Pediatric Intraocular Retinoblastoma
Extraocular Retinoblastoma	Pediatric Extraocular Retinoblastoma
Childhood Infratentorial Neoplasm	Pediatric Infratentorial Tumor
Supraglottis Neoplasm	Neoplasm Of Supraglottis Supraglottic Tumor
Orbital Cellulitis	Cellulitis Of Orbit
Acute Orbital Inflammation	Acute Inflammation Of Orbit
Rectosigmoid Cancer	Rectosigmoid Junction Cancer Malignant Neoplasm Of Rectosigmoid Junction Malignant Neoplasm Of Rectosigmoid Malignant Rectosigmoid Tumor Malignant Tumor Of Rectosigmoid Junction
Anal Canal Carcinoma	Anal Canal Cancer Anal Canal And Perianal Gland Carcinoma Carcinoma Of The Anal Canal Carcinoma Of Anal Canal
Supraglottis Cancer	Malignant Tumor Of Supraglottis Supraglottis Ca Larynx - Supraglottis Malignant Neoplasm Of Extrinsic Larynx Malignant Neoplasm Of Supraglottis Malignant Supraglottic Tumor Neoplasm Of Supraglottis
Subglottis Benign Neoplasm	Subglottic Tumor
Parotid Gland Cancer	Cancer Of Parotid Gland Parotid Neoplasms Malignant Neoplasm Of The Parotid Malignant Tumor Of Parotid Gland Parotid Cancer Parotid Neoplasm Parotid Gland Carcinoma Cancer Of Parotid Malignant Tumour Of Parotid Gland Parotid Duct Cancer Parotid Ductal Cancer Parotid Glandular Cancer Primary Malignant Neoplasm Of Parotid Gland
Epiglottis Cancer	Epiglottic Cancer Malignant Tumor Of Epiglottis
Rectal Benign Neoplasm	Neoplasm Of Rectum Rectal Tumor Rectum Neoplasm Neoplasm Of The Rectum Rectal Neoplasms Primary Rectal Cancer Rectal Ampulla Cancer Cancer Of The Rectum Carcinoma Of Rectum Primary Malignant Neoplasm Of Rectum Rectal Cancer Rectal Carcinoma
Gastric Adenosquamous Carcinoma	Adenosquamous Carcinoma Of Stomach
Rectum Adenocarcinoma	Rectal Adenocarcinoma Adenocarcinoma Of Rectum
Anal Canal Adenocarcinoma	Adenocarcinoma Of The Anal Canal Adenocarcinoma Of Anal Canal
Lymphocele	Lymph Cyst Lymphocele Adverse Event
Laryngeal Benign Neoplasm	Laryngeal Tumor Larynx Neoplasm Neoplasm Of Larynx Laryngeal Cancer Laryngeal Carcinoma Cancer Of Larynx
Rectum Cancer	Malignant Neoplasm Of Rectum Rectal Cancer Cancer Of Rectum Carcinoma Of Rectum Carcinoma Of The Rectum Malignant Rectal Tumor Malignant Rectum Tumor Malignant Tumor Of Rectum Rectal Carcinoma Rectal Cancers Cancer, Rectal
Female Stress Incontinence	Female Urinary Stress Incontinence Stress Incontinence - Female
Anus Cancer	Anal Cancer Anal Carcinoma Malignant Anal Tumor Cancer Of The Anus Malignant Neoplasm Of Anus Anus Neoplasms
Retinitis Pigmentosa 50	RP50 Retinitis Pigmentosa, Concentric Retinitis Pigmentosa-50 Retinitis Pigmentosa Concentric
Gastric Diffuse Adenocarcinoma	Diffuse Gastric Adenocarcinoma Carcinoma, Diffuse Type
Rectal Disease	Rectal Diseases Rectal Disorders
Hypopharynx Cancer	Hypopharyngeal Cancer Malignant Neoplasm Of Hypopharynx Hypopharyngeal Neoplasms Hypopharyngeal Carcinoma Malignant Hypopharyngeal Tumor Malignant Tumor Of Hypopharynx Malignant Tumour Of Hypopharynx
Anus Disease	Anal Fissure Ulcer Of Anus Anus Diseases Anal Disease Anal Fissure And Fistula Anal Ulcer Fissure In Ano Nontraumatic Tear Of Anus Solitary Anal Ulcer Abnormality Of The Anus Anal Disorders Ulcer Of Anus And Rectum Solitary Ulcer Of Anus Stercoral Ulcer Of Anus
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-103555	NPEC-caged-(1S,3R)-ACPD		/	Unkown
HY-RS01825	CAGE1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CAGE1	MGD	MGI:1918463
Rattus norvegicus	CAGE1	RGD	RGD:1306102