LURAP1 - leucine rich adaptor protein 1 Gene
Also Known as LRP35A; LRAP35a; C1orf190
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 541468
Summary
Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of cytokine production. Located in cytosol. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in thyroid (RPKM 5.9), testis (RPKM 4.8) and 20 other tissues.
LURAP1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001013615.3 | NP_001013633.1 | leucine rich adaptor protein 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16189514 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in positive regulation of canonical NF-kappaB signal transduction |
IDA
IDA: Inferred from direct assay
|
21048106 | GOA |
| involved in positive regulation of cytokine production |
IDA
IDA: Inferred from direct assay
|
21048106 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
21048106 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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LURAP1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
LURAP1 | Q96LR2 | ABI2 | Homo sapiens | Q9NYB9-2 | 32296183 | |
|
Intra
|
LURAP1 | Q96LR2 | SHFL | Homo sapiens | Q9NUL5-4 | 32296183 | |
|
Intra
|
LURAP1 | Q96LR2 | PRPF31 | Homo sapiens | Q8WWY3 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | PRPF31 | Homo sapiens | Q8WWY3 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | HAUS1 | Homo sapiens | Q96CS2 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | HAUS1 | Homo sapiens | Q96CS2 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | FGFR3 | Homo sapiens | P22607 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | FGFR3 | Homo sapiens | P22607 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | FGFR3 | Homo sapiens | P22607 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | HRAS | Homo sapiens | P01112 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | HRAS | Homo sapiens | P01112 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | HRAS | Homo sapiens | P01112 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | GSN | Homo sapiens | P06396 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | GSN | Homo sapiens | P06396 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | GSN | Homo sapiens | P06396 | 32814053 | |
|
Intra
|
LURAP1 | Q96LR2 | TPM3 | Homo sapiens | P06753 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | TPM3 | Homo sapiens | P06753 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | TXLNB | Homo sapiens | Q8N3L3 | 31515488 | |
|
Intra
|
LURAP1 | Q96LR2 | TXLNB | Homo sapiens | Q8N3L3 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | TXLNB | Homo sapiens | Q8N3L3 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | TXLNB | Homo sapiens | Q8N3L3 | 33961781 | |
|
Intra
|
LURAP1 | Q96LR2 | HMG20A | Homo sapiens | Q9NP66 | 32296183 | |
|
Intra
|
LURAP1 | Q96LR2 | ZNF417 | Homo sapiens | Q8TAU3 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | ZNF417 | Homo sapiens | Q8TAU3 | 25416956 | |
|
Intra
|
LURAP1 | Q96LR2 | ENKD1 | Homo sapiens | Q9H0I2 | 32296183 | |
|
Intra
|
LURAP1 | Q96LR2 | CSNK1D | Homo sapiens | P48730 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction