TPM3 - tropomyosin 3 Gene

Also Known as TM3; TM5; TRK; CFTD; NEM1; TM-5; TM30; CAPM1; TM30nm; TPM3nu; TPMsk3; hscp30; HEL-189; HEL-S-82p; OK/SW-cl.5

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7170

About TPM3

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:154,155,308-154,192,100 (from NCBI)

This gene has 27 transcripts (splice variants), 119 orthologues, 3 paralogues and is associated with 83 phenotypes. Ubiquitous expression in bone marrow (RPKM 43.6), appendix (RPKM 31.3) and 25 other tissues.

Summary

This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of Other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and Other muscle disorders. This locus is involved in translocations with Other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

TPM3 Products (15)

mRNA	Protein	Name
NM_001043351.2	NP_001036816.1	tropomyosin alpha-3 chain isoform Tpm3.2cy
NM_001043352.2	NP_001036817.1	tropomyosin alpha-3 chain isoform Tpm3.7cy
NM_001043353.2	NP_001036818.1	tropomyosin alpha-3 chain isoform Tpm3.4cy
NM_001278188.2	NP_001265117.1	tropomyosin alpha-3 chain isoform 6
NM_001278189.2	NP_001265118.1	tropomyosin alpha-3 chain isoform Tpm3.5cy
NM_001278190.2	NP_001265119.1	tropomyosin alpha-3 chain isoform 8
NM_001278191.2	NP_001265120.1	tropomyosin alpha-3 chain isoform 9
NM_001349679.2	NP_001336608.1	tropomyosin alpha-3 chain isoform Tpm3.3cy
NM_001364679.2	NP_001351608.1	tropomyosin alpha-3 chain isoform 10
NM_001364680.2	NP_001351609.1	tropomyosin alpha-3 chain isoform 11
NM_001364681.2	NP_001351610.1	tropomyosin alpha-3 chain isoform 12
NM_001364682.1	NP_001351611.1	tropomyosin alpha-3 chain isoform 13
NM_001364683.1	NP_001351612.1	tropomyosin alpha-3 chain isoform Tpm3.5cy
NM_152263.4	NP_689476.2	tropomyosin alpha-3 chain isoform Tpm3.12st
NM_153649.4	NP_705935.1	tropomyosin alpha-3 chain isoform Tpm3.1cy

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in stress fiber	IDA IDA: Inferred from direct assay	16236705	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TPM3 Protein Structure

Tropomyosin

0
100
200
285 a.a.

Protein Preferred Names	Protein Names
tropomyosin alpha-3 chain	alpha-tropomyosin, slow skeletal

TPM3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Array	32296183
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	SLC	25910212
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Validated Y2H	25910212
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Prey Pooling	25416956
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Array	25910212
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Validated Y2H	32296183
Intra	TPM3	P06753	CCHCR1	Homo sapiens	Q8TD31-3	Y2H Array	25416956
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6-2	Y2H Array	25416956
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6-2	Y2H Prey Pooling	25416956
Intra	TPM3	P06753	PHLDB3	Homo sapiens	Q6NSJ2-2	Validated Y2H	32296183
Intra	TPM3	P06753	PHLDB3	Homo sapiens	Q6NSJ2-2	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	PHLDB3	Homo sapiens	Q6NSJ2-2	Y2H Array	32296183
Intra	TPM3	P06753	HSF4	Homo sapiens	Q9ULV5-2	Y2H Array	32296183
Intra	TPM3	P06753	HSF4	Homo sapiens	Q9ULV5-2	Validated Y2H	32296183
Intra	TPM3	P06753	HSF4	Homo sapiens	Q9ULV5-2	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	TNNT1	Homo sapiens	P13805-3	Validated Y2H	25910212
Intra	TPM3	P06753	TNNT1	Homo sapiens	P13805-3	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	TNNT1	Homo sapiens	P13805-3	Y2H Array	25910212
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	SLC	25910212
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	Validated Y2H	25910212
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	Validated Y2H	32296183
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	Y2H Array	25910212
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	BFG-2H	27107012
Intra	TPM3	P06753	TFPT	Homo sapiens	P0C1Z6	Y2H Array	32296183
Intra	TPM3	P06753	TPM4	Homo sapiens	P67936	Validated Y2H	32296183
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Validated Y2H	25910212
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Y2H Array	31515488
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Y2H Array	25910212
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Validated Y2H	25416956
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Validated Y2H	32296183
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Y2H Array	25416956
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	HSF2	Homo sapiens	Q03933	Y2H Array	32296183
Intra	TPM3	P06753	VPS52	Homo sapiens	Q8N1B4	Validated Y2H	25416956
Intra	TPM3	P06753	FAM9C	Homo sapiens	Q8IZT9	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	FAM9C	Homo sapiens	Q8IZT9	Validated Y2H	32296183
Intra	TPM3	P06753	FAM9C	Homo sapiens	Q8IZT9	Y2H Array	32296183
Intra	TPM3	P06753	SNAPIN	Homo sapiens	O95295	Y2H Array	32296183
Intra	TPM3	P06753	SNAPIN	Homo sapiens	O95295	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	PSMC5	Homo sapiens	P62195	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	PSMC5	Homo sapiens	P62195	Validated Y2H	32296183
Intra	TPM3	P06753	PSMC5	Homo sapiens	P62195	Y2H Array	32296183
Intra	TPM3	P06753	TAB2	Homo sapiens	Q9NYJ8	Validated Y2H	32296183
Intra	TPM3	P06753	CAVIN3	Homo sapiens	Q969G5	Anti Tag CoIP	33961781
Intra	TPM3	P06753	CAVIN3	Homo sapiens	Q969G5	Validated Y2H	32296183
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Validated Y2H	25910212
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Array	31515488
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Prey Pooling	25416956
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Array	25910212
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Validated Y2H	25416956
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Array	25416956
Intra	TPM3	P06753	OIP5	Homo sapiens	O43482	Y2H Array	32296183
Intra	TPM3	P06753	SYCE1	Homo sapiens	Q8N0S2	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	SYCE1	Homo sapiens	Q8N0S2	SLC	25910212
Intra	TPM3	P06753	SYCE1	Homo sapiens	Q8N0S2	Validated Y2H	25910212
Intra	TPM3	P06753	SYCE1	Homo sapiens	Q8N0S2	Y2H Array	25910212
Intra	TPM3	P06753	SYCE1	Homo sapiens	Q8N0S2	Validated Y2H	25416956
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Validated Y2H	32296183
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Y2H Array	25910212
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Validated Y2H	25416956
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Y2H Array	32296183
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Y2H Pooling	16189514
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	SLC	25910212
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	KXD1	Homo sapiens	Q9BQD3	Validated Y2H	25910212
Intra	TPM3	P06753	NUP54	Homo sapiens	Q7Z3B4	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	NUP54	Homo sapiens	Q7Z3B4	Y2H Array	32296183
Intra	TPM3	P06753	NUP54	Homo sapiens	Q7Z3B4	Validated Y2H	32296183
Intra	TPM3	P06753	THAP7	Homo sapiens	Q9BT49	Validated Y2H	32296183
Intra	TPM3	P06753	LURAP1	Homo sapiens	Q96LR2	Y2H Array	31515488
Intra	TPM3	P06753	LURAP1	Homo sapiens	Q96LR2	Validated Y2H	25416956
Intra	TPM3	P06753	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	THAP1	Homo sapiens	Q9NVV9	Validated Y2H	32296183
Intra	TPM3	P06753	THAP1	Homo sapiens	Q9NVV9	Y2H Array	32296183
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Prey Pooling	25416956
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Y2H	21516116
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Validated Y2H	25910212
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Array	25910212
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Validated Y2H	25416956
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Validated Y2H	32296183
Intra	TPM3	P06753	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Array	32296183
Intra	TPM3	P06753	IFIT3	Homo sapiens	O14879	Validated Y2H	25910212
Intra	TPM3	P06753	IFIT3	Homo sapiens	O14879	Y2H Bait-Prey Pool	25910212
Intra	TPM3	P06753	IFIT3	Homo sapiens	O14879	SLC	25910212
Intra	TPM3	P06753	IFIT3	Homo sapiens	O14879	Y2H Array	25910212
Intra	TPM3	P06753	TNNI1	Homo sapiens	P19237	Validated Y2H	32296183
Intra	TPM3	P06753	TNNI1	Homo sapiens	P19237	Y2H Array	32296183
Intra	TPM3	P06753	TNNI1	Homo sapiens	P19237	Y2H Prey Pooling	32296183
Intra	TPM3	P06753	C1orf216	Homo sapiens	Q8TAB5	Validated Y2H	32296183
Intra	TPM3	P06753	LCA5L	Homo sapiens	O95447	Y2H Array	31515488
Intra	TPM3	P06753	LCA5L	Homo sapiens	O95447	Y2H Prey Pooling	25416956
Intra	TPM3	P06753	TSKS	Homo sapiens	Q9UJT2	Validated Y2H	32296183
Intra	TPM3	P06753	ATXN1	Homo sapiens	P54253	Y2H Pooling	32814053
Intra	TPM3	P06753	ATXN1	Homo sapiens	P54253	Validated Y2H	32814053
Intra	TPM3	P06753	ATXN1	Homo sapiens	P54253	Y2H Array	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant TPM3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71083	TPM3 Protein, Human	P06753-2 (M1-M248)	≥ 90%, as determined by reducing SDS-PAGE.

TPM3 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P810812	Tropomyosin 3 Antibody (YA10055)	WB	Human, Mouse

Related Diseases

Diseases	Alias
Nemaline Myopathy 1	Cap Myopathy 1 NEM1 Nemaline Myopathy 1, Autosomal Dominant Or Recessive Nemaline Myopathy, Type 1 CAPM1 Cap Disease Cap Myopathy Tpm3-Related Nemaline Myopathy 1 Autosomal Dominant Or Recessive Myopathy, Nemaline, Type 1 Cap Myopathy
Myopathy, Congenital, With Fiber-Type Disproportion	CFTD Fiber-Type Disproportion Myopathy, Congenital Cftdm Myopathy, Congenital, With Fiber-Type Disproportion 1 Congenital Fiber-Type Disproportion Myopathy Myopathy, Congenital, With Fiber Type Disproportion
Congenital Fiber-Type Disproportion	Congenital Fiber Type Disproportion Cftdm Congenital Myopathy With Fiber Type Disproportion Cftd Congenital Fiber-Type Disproportion Myopathy Fiber-Type Disproportion Myopathy, Congenital Myopathy, Congenital With Fiber-Type Disproportion
Cap Myopathy	Cap Disease Congenital Myopathy With Caps
Congenital Generalized Hypercontractile Muscle Stiffness Syndrome
Inflammatory Myofibroblastic Tumor	Inflammatory Fibrosarcoma
Intermediate Congenital Nemaline Myopathy	Intermediate Nemaline Myopathy Intermediate Congenital Nm
Childhood-Onset Nemaline Myopathy	Mild Nemaline Myopathy Nemaline Myopathy, Childhood Onset
Myopathy	Muscular Diseases Myopathies
Lipofibromatosis-Like Neural Tumor
Congenital Fibrosarcoma	Infantile Fibrosarcoma
Childhood Fibrosarcoma	Pediatric Fibrosarcoma
Epithelioid Inflammatory Myofibroblastic Sarcoma
Congenital Structural Myopathy
Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome	Jacobs Syndrome Arthropathy-Camptodactyly Syndrome Pericarditis-Arthropathy-Camptodactyly Syndrome Xyy Syndrome Pac Syndrome Cacp Syndrome CACP Fibrosing Serositis, Familial Camptodactyly-Arthropathy-Pericarditis Syndrome Cap Syndrome 47, Xyy Syndrome 47,Xyy Syndrome Double Y Syndrome Camptodactyly-Arthropathy-Coxa-Vara-Pericarditis Syndrome Hypertrophic Synovitis, Congenital Familial Congenital Familial Hypertrophic Synovitis Xyy Karyotype Y Disomy Yy Syndrome Familial Fibrosing Serositis Disomy Y Double Y Camptodactyly Arthropathy Coxa Vara Pericarditis Syndrome Arthropathy Camptodactyly Syndrome Camptodactyly Arthropathy Pericarditis Syndrome Pericarditis Arthropathy Camptodactyly Syndrome Jacob'S Syndrome 47,Xyy Cdags Syndrome
Congenital Mesoblastic Nephroma	Mesoblastic Nephroma Nephroma, Mesoblastic
Spitzoid Melanoma	Atypical Spitz Nevus
Mesenchymal Cell Neoplasm	Benign Miscellaneous Mesenchymal Tumor Mesenchymal Tumor Mesenchymal Tumors
Infantile Myofibromatosis	Lipofibromatosis Myofibromatosis
Pulmonary Plasma Cell Granuloma	Plasma Cell Granuloma, Pulmonary Granuloma, Plasma Cell, Pulmonary Lymphocytic Pseudotumor Of Lung Sclerosing Hemangiocytoma Of Lung
Childhood Kidney Cell Carcinoma	Pediatric Renal Cell Carcinoma Childhood Renal Cell Carcinoma
Nemaline Myopathy 2	NEM2 Nemaline Myopathy 2, Autosomal Recessive Nemaline Myopathy, Type 2 Neb-Related Nemaline Myopathy Myopathy, Nemaline, Type 2
Hypotonia
Batten-Turner Congenital Myopathy	Congenital Myopathy Batten Turner Congenital Myopathy Myopathy Congenital Myopathy, Congenital Myotonia Congenita Benign Congenital Myopathy
Mammary Analogue Secretory Carcinoma
Arthrogryposis, Distal, Type 1a	Distal Arthrogryposis Type 1 Digitotalar Dysmorphism DA1A Da1 Amcd1 Arthrogryposis, Distal, Type 2b4 Distal Arthrogryposis Type 1a Arthrogryposis, Distal, Type 1 Arthrogryposis Multiplex Congenita Distal Type 1 Arthrogryposis Multiplex Congenita, Distal Type 1 Arthrogryposis Multiplex Congenita, Distal, Type I Distal Arthrogryposis Type 1b Arthrogryposis, Distal, 1a Amc Arthrogryposis Multiplex Congenita Arthrogryposis, Distal, 2b4 DA2B4 Arthrogryposis Multiplex Congenita, Distal, Type 1 Arthrogryposis
Distal Arthrogryposis	Arthrogryposis Multiplex Congenita Arthrogryposis Congenital Multiple Arthrogryposis Congenital Arthromyodysplasia Fibrous Ankylosis Of Multiple Joints Guerin-Stern Syndrome Guérin-Stern Syndrome Myodystrophia Fetalis Deformans Otto Syndrome Rocher-Sheldon Syndrome Rossi Syndrome Amc Multiple Congenital Arthrogryposis Arthrogryposis Syndrome Arthrogryposis, Distal Distal Arthrogryposis Syndrome Freeman-Sheldon Syndrome Arthrogryposis, Distal, Type 2b Congenital Multiplex Arthrogryposis Amyoplasia Congenita Congenital Amyoplasia Amc - [Arthrogryposis Multiplex Congenita]
Kidney Cortex Disease
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-137465	CG428	Degrader	98.26%	Phase 2

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-124689	TR-100	Inhibitor	99.0%	Unkown
HY-157542	CG428-NEG	Control	97.6%	Unkown
HY-131244	ALK-IN-9	Inhibitor	/	Unkown
HY-175271	JWJ-01-378		/	Unkown
HY-RS14938	TPM3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-164514	NMS-P626	Inhibitor	/	Unkown
HY-RS18503	Tpm3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24985	Tpm3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TPM3	VGNC	VGNC:47743
Rattus norvegicus	TPM3	RGD	RGD:621546
Mus musculus	TPM3	MGD	MGI:1890149
Bos taurus	TPM3	VGNC	VGNC:36253
Felis catus	TPM3	VGNC	VGNC:107956
Macaca mulatta	TPM3	VGNC	VGNC:78635
Others	TPM3	NCBI