Tropomyosin 3 Antibody (YA10055)
(Synonyms: Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3)Tropomyosin 3 Antibody (YA10055) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to Tropomyosin 3.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
Tropomyosin 3 Antibody (YA10055) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to Tropomyosin 3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 33 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
Purified recombinant protein of human Tropomyosin 3.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Tropomyosin 3 binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments
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Subcellular Localization
Cytoplasm, cytoskeleton
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Isoforms & Post-Translational Modification
Tropomyosin 3 has 7 isoforms, P06753-1: amino acid length is 285, molecular weight is 32950 Da (predicted); P06753-2: amino acid length is 248, molecular weight is 29033 Da (predicted); P06753-3: amino acid length is 247, molecular weight is 28955 Da (predicted); P06753-4: amino acid length is 247, molecular weight is 28793 Da (predicted); P06753-5: amino acid length is 248, molecular weight is 28870 Da (predicted); P06753-6: amino acid length is 248, molecular weight is 28922 Da (predicted); P06753-7: amino acid length is 158, molecular weight is 18603 Da (predicted).
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Subunit
Homodimer.
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SwissProt ID
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Synonyms
Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3
Documentation