CSNK1D - casein kinase 1 delta Gene

Homo sapiens

Also known as ASPS; CKId; HCKID; FASPS2; CKIdelta; CKI-delta

Gene ID: 1453 | Gene type: protein coding

About CSNK1D

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,239,019-82,273,750 (from NCBI)

This gene has 26 transcripts (splice variants), 264 orthologues, 12 paralogues and is associated with 2 phenotypes. Ubiquitous expression in spleen (RPKM 17.2), prostate (RPKM 17.2) and 25 other tissues.

Summary

This gene is a member of the Casein Kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of Apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]

CSNK1D Products(3)

mRNA	Protein	Name
NM_001363749.2	NP_001350678.1	casein kinase I isoform delta isoform 3
NM_001893.6	NP_001884.2	casein kinase I isoform delta isoform 1
NM_139062.4	NP_620693.1	casein kinase I isoform delta isoform 2

CSNK1D Protein Structure

Pkinase

0
100
200
300
415 a.a.

Protein Preferred Names

Protein Names

casein kinase I isoform delta

casein kinase I

tau-protein kinase CSNK1D

Related Diseases

Diseases

Alias

Advanced Sleep Phase Syndrome, Familial, 2

Advanced Sleep Phase Syndrome 2	FASPS2
Advanced Sleep-Phase Syndrome, Familial, 2	Familial Advanced Sleep Phase Syndrome 2
Sleep Phase Syndrome, Advanced, Familial, Type 2

Advanced Sleep Phase Syndrome

Fasps	Familial Advanced Sleep-Phase Syndrome
Advanced Sleep Phase Syndrome, Familial	Familial Advanced Sleep Phase Syndrome
Sleep Phase Syndrome, Advanced, Familial	Advanced Sleep-Phase Syndrome, Familial

Migraine, Familial Hemiplegic, 1

FHM1	Mhp1
Fhm	Familial Hemiplegic Migraine 1
Migraine, Familial Hemiplegic, 1, With Progressive Cerebellar Ataxia	Familial Hemiplegic Migraine1 With Progressive Cerebellar Ataxia
Migraine Familial Hemiplegic With Progressive Cerebellar Ataxia	Migraine, Hemiplegic, Familial, Type 1
Hemiplegic Migraine, Familial Type 1

Delayed Sleep Phase Disorder

Delayed Sleep Phase Syndrome	Delayed Sleep Phase Syndrome, Susceptibility To
DSPD	Delayed Sleep Phase Disorder, Susceptibility To
DSPS	Sleep Phase, Delayed, Disorder
Sleep Phase Syndrome, Delayed, Susceptibility To

Migraine, Familial Hemiplegic, 2

FHM2	Mhp2
Migraine, Familial Basilar	Familial Hemiplegic Migraine 2
Familial Hemiplegic Migraine-2	Familiar Basilar Migraine
Migraine, Hemiplegic, Familial, Type 2

Sleep Disorder

Sleep Disorders

Non-Organic Sleep Disorder

Migraine, Familial Hemiplegic, 3

FHM3	Familial Hemiplegic Migraine 3
Mhp3	Migraine, Hemiplegic, Familial, Type 3

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Major Depressive Disorder

Seasonal Affective Disorder	Unipolar Depression
Depression	MDD
Depressive Disorder	Unipolar Depression, Susceptibility To
Major Depressive Disorder 1	Major Depressive Disorder, Response To Citalopram Therapy In
Major Depressive Disorder 2	Winter Depression
Single Major Depressive Episode	Sad
Clinical Depression	Major Depression
Depressive Syndrome	Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment
Seasonal Affective Disorder, Susceptibility To	Recurrent Major Depression
Affective Disorder, Seasonal	Depression In A Seasonal Pattern
Depression	Seasonal
Major Depressive Disorder With A Seasonal Pattern	Seasonal Depression
Seasonal Mood Disorder	Mental Depression
Recurrent Major Depressive Episodes

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Migraine With Or Without Aura 1

Migraine	Migraine With Or Without Aura, Susceptibility To, 1
Migraine Disorder	Migraine Variant
Migraines	Migraine Disorders
Mgr1	Mgau
Ma	Migraine With Or Without Aura
Classic Migraine	Common Migraine
Disorder, Migraine	Headache Migraine
Headache Migrainous	Migraine Headache
Migraine Syndrome	Headache Including Migraine
Migraine, Susceptibility To

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-145939	BAY-888	Inhibitor	98.35%	Unkown
HY-RS03246	CSNK1D Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CSNK1D	VGNC	VGNC:39667
Felis catus	CSNK1D	VGNC	VGNC:97391
Macaca mulatta	CSNK1D	VGNC	VGNC:81382
Mus musculus	CSNK1D	MGD	MGI:1355272
Rattus norvegicus	CSNK1D	RGD	RGD:71031
Bos taurus	CSNK1D	VGNC	VGNC:27766
Others	CSNK1D	NCBI

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