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51233

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By Targets:	Antibiotic (1) Bacterial (2) Beta-lactamase (2) Dengue Virus (1) Estrogen Receptor/ERR (1) Flavivirus (1) Fungal (1) HBV (1) MicroRNA (16) Parasite (1) PD-1/PD-L1 (1) PROTACs (1) Ser/Thr Protease (1)
By Research Areas:	Cancer (20) Infection (6) Metabolic Disease (1)
Oligonucleotides:	miRNA mimics (4) miRNA agomirs (4) miRNA antagomirs (4) MicroRNAs (16) miRNA inhibitors (4)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-109124

Taniborbactam 15+ Cited Publications VNRX-5133	Beta-lactamase Bacterial	Infection
Taniborbactam (VNRX-5133) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC₅₀s of 8-530 nM. Taniborbactam has IC₅₀s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam is against Gram-negative bacteria .

HY-109124A

Taniborbactam hydrochloride 15+ Cited Publications VNRX-5133 hydrochloride	Beta-lactamase Bacterial	Infection
Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC₅₀s of 8-530 nM. Taniborbactam hydrochloride has IC₅₀s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria .

HY-117430

Hymeglusin F-244; 1233A; L-659699	Flavivirus Dengue Virus Antibiotic	Infection Metabolic Disease Cancer
Hymeglusin, as a fungal β-lactone antibiotic, is a HMG-CoA synthase inhibitor (IC₅₀ = 0.12 μM). Hymeglusin covalently modifies the active Cys ¹²⁹ residue of the enzyme .

HY-125706

1233B	Fungal	Infection
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .

HY-R00128

*hsa-miR-1233-3p mimic*	MicroRNA	Cancer
hsa-miR-1233-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-1233-3p mimic hsa-miR-1233-3p mimic

HY-151066

BMS-1233	PD-1/PD-L1	Cancer
BMS-1233 is an orally active inhibitor for programmed cell death-ligand 1 (PD-L1), with IC₅₀ of 14.5 nM. BMS-1233 promotes cell death of HepG2 in a Jurkat T cell and HepG2 cell co-culture model, exhibits antitumor activity against melanoma in mouse model .

HY-161371

VD5123	Ser/Thr Protease	Cancer
VD5123 is a serine protease inhibitor. VD5123 inhibits TMPRS2, HGFA, matriptase, hepsin with IC₅₀s of 15, 3980, 140, 37 nM respectively. VD5123 can be used for antiviral research, such as SARS-CoV-2 and broad panel of coronaviruses and influenza viruses .

HY-144319

SHR5133	HBV	Infection
SHR5133 is a highly potent, orally active HBV capsid assembly modulator. SHR5133 displays HBV DNA reduction (EC₅₀=26.6 nM) .

HY-169367

ERD-1233	PROTACs Estrogen Receptor/ERR	Cancer
ERD-1233 is a potent and orally active estrogen receptor PROTAC degrader, with the DC₅₀ of 0.9 nM. ERD-1233 plays an important role in ER ⁺ breast cancer research (Pink: ligand for target protein (HY-201580); Black: linker (HY-W889109); Blue: E3 ligase ligand (HY-W1009348)) .

HY-R03267

*mmu-miR-5123* mimic**	MicroRNA	Cancer
mmu-miR-5123 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5123 mimic mmu-miR-5123 mimic

HY-R03280

*mmu-miR-5133* mimic**	MicroRNA	Cancer
mmu-miR-5133 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5133 mimic mmu-miR-5133 mimic

HY-R00129

*hsa-miR-1233-5p mimic*	MicroRNA	Cancer
hsa-miR-1233-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-1233-5p mimic hsa-miR-1233-5p mimic

HY-178326

NEU-5123	Parasite	Infection
NEU-5123 is a human kinase inhibitor with potent inhibitory activity to several kinases. NEU-5123 is a Trypanosome proliferation inhibitor. NEU-5123 can be used for the research of infection .

HY-RI03280A

*mmu-miR-5133* antagomir**	MicroRNA	Cancer
mmu-miR-5133 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5133 antagomir mmu-miR-5133 antagomir

HY-RI03267

*mmu-miR-5123* inhibitor**	MicroRNA	Cancer
mmu-miR-5123 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5123 inhibitor mmu-miR-5123 inhibitor

HY-RI03267A

*mmu-miR-5123* antagomir**	MicroRNA	Cancer
mmu-miR-5123 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5123 antagomir mmu-miR-5123 antagomir

HY-RI03280

*mmu-miR-5133* inhibitor**	MicroRNA	Cancer
mmu-miR-5133 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5133 inhibitor mmu-miR-5133 inhibitor

HY-R03267A

*mmu-miR-5123* agomir**	MicroRNA	Cancer
mmu-miR-5123 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5123 agomir mmu-miR-5123 agomir

HY-R03280A

*mmu-miR-5133* agomir**	MicroRNA	Cancer
mmu-miR-5133 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5133 agomir mmu-miR-5133 agomir

HY-RI00129A

*hsa-miR-1233-5p antagomir*	MicroRNA	Cancer
hsa-miR-1233-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1233-5p antagomir hsa-miR-1233-5p antagomir

HY-RI00128

*hsa-miR-1233-3p inhibitor*	MicroRNA	Cancer
hsa-miR-1233-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-1233-3p inhibitor hsa-miR-1233-3p inhibitor

HY-RI00128A

*hsa-miR-1233-3p antagomir*	MicroRNA	Cancer
hsa-miR-1233-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1233-3p antagomir hsa-miR-1233-3p antagomir

HY-RI00129

*hsa-miR-1233-5p inhibitor*	MicroRNA	Cancer
hsa-miR-1233-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-1233-5p inhibitor hsa-miR-1233-5p inhibitor

HY-R00129A

*hsa-miR-1233-5p agomir*	MicroRNA	Cancer
hsa-miR-1233-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1233-5p agomir hsa-miR-1233-5p agomir

HY-R00128A

*hsa-miR-1233-3p agomir*	MicroRNA	Cancer
hsa-miR-1233-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-1233-3p agomir hsa-miR-1233-3p agomir

1233B	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Fungal
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .

Host:	Mouse (3) Rabbit (2)
Reactivity:	Human (5) Rat (1) Mouse (1) Dog (1) Pig (1)
Application:	IHC-P (3) ICC/IF (2) WB (3)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81488

	TNS4/CTEN Antibody (YA1233) PP14434; CTEN; TNS4; Tensin-4; C-terminal tensin-like protein	IHC-P	Human
	TNS4/CTEN Antibody (YA1233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TNS4/CTEN.

HY-P81488A

	TNS4/CTEN Antibody (YA1233)(PBS only) PP14434; CTEN; TNS4; Tensin-4; C-terminal tensin-like protein	IHC-P	Human
	TNS4/CTEN Antibody (YA1233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TNS4/CTEN.

HY-P85441

	LRRFIP1 Antibody (YA5133) LRRFIP1; GCF2; TRIP; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein	WB	Human
	LRRFIP1 Antibody (YA5133) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LRRFIP1.

HY-P85431

	HAUSP/USP7 Antibody (YA5123) USP7; HAUSP; Ubiquitin carboxyl-terminal hydrolase 7; Deubiquitinating enzyme 7; Herpesvirus-associated ubiquitin-specific protease; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7	WB, ICC/IF	Human, Mouse, Rat, Dog, Pig
	HAUSP/USP7 Antibody (YA5123) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HAUSP/USP7.

HY-P85541

	CHRDL1 Antibody (YA5233) CHL; chordin like 1; Chordin-like protein 1; CHRDL1; CRDL1_HUMAN; dA141H5.1; neuralin 1; Neuralin-1; Neurogenesin-1; NRLN1; Ventroptin; VOPT.	WB, IHC-P, ICC/IF	Human
	CHRDL1 Antibody (YA5233) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CHRDL1.

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Cat. No.	Product Name		Classification

HY-R00128

*hsa-miR-1233-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-1233-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03267

*mmu-miR-5123* mimic**		MicroRNAs miRNA mimics
mmu-miR-5123 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03280

*mmu-miR-5133* mimic**		MicroRNAs miRNA mimics
mmu-miR-5133 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R00129

*hsa-miR-1233-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-1233-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03280A

*mmu-miR-5133* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5133 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03267

*mmu-miR-5123* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5123 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03267A

*mmu-miR-5123* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5123 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03280

*mmu-miR-5133* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5133 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03267A

*mmu-miR-5123* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5123 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03280A

*mmu-miR-5133* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5133 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00129A

*hsa-miR-1233-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-1233-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00128

*hsa-miR-1233-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-1233-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00128A

*hsa-miR-1233-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-1233-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00129

*hsa-miR-1233-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-1233-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R00129A

*hsa-miR-1233-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-1233-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00128A

*hsa-miR-1233-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-1233-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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51233

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