ZNF618 - zinc finger protein 618 Gene
Also Known as NEDD10; FP13169
Species: Homo sapiens
Summary
Enables chromatin-protein adaptor activity; identical protein binding activity; and transcription coregulator binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in pericentric heterochromatin. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in ovary (RPKM 1.9), kidney (RPKM 1.8) and 25 other tissues.
ZNF618 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001318040.2 | NP_001304969.1 | zinc finger protein 618 isoform 2 |
| NM_001318041.2 | NP_001304970.1 | zinc finger protein 618 isoform 3 |
| NM_001318042.2 | NP_001304971.1 | zinc finger protein 618 isoform 4 |
| NM_133374.3 | NP_588615.2 | zinc finger protein 618 isoform 1 |
| Molecular Function GO Annotation | Evidence | Referencias | Source |
|---|---|---|---|
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables transcription coregulator binding |
IPI
IPI: Inferred from physical interaction
|
27129234 | GOA |
| Biological Process GO Annotation | Evidence | Referencias | Source |
|---|---|---|---|
| involved in positive regulation of chromatin binding |
IDA
IDA: Inferred from direct assay
|
27129234 | GOA |
| Cellular Component GO Annotation | Evidence | Referencias | Source |
|---|---|---|---|
| located in chromatin |
IDA
IDA: Inferred from direct assay
|
27129234 | GOA |
| located in pericentric heterochromatin |
IDA
IDA: Inferred from direct assay
|
27129234 | GOA |
ZNF618 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Referencias |
|---|---|---|---|---|---|---|---|
|
Intra
|
ZNF618 | Q5T7W0 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | G3BP2 | Homo sapiens | Q9UN86-2 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | DPPA3 | Homo sapiens | Q6W0C5 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | TBC1D13 | Homo sapiens | Q9NVG8 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | UBL5 | Homo sapiens | Q9BZL1 | 32296183 | |
|
Intra
|
ZNF618 | Q5T7W0 | NTAQ1 | Homo sapiens | Q96HA8 | 32296183 |