ZNF618 - zinc finger protein 618 Gene

Also Known as NEDD10; FP13169

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 114991

Summary

Enables chromatin-protein adaptor activity; identical protein binding activity; and transcription coregulator binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in pericentric heterochromatin. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in ovary (RPKM 1.9), kidney (RPKM 1.8) and 25 other tissues.

ZNF618 Products (4)

mRNA Protein Name
NM_001318040.2 NP_001304969.1 zinc finger protein 618 isoform 2
NM_001318041.2 NP_001304970.1 zinc finger protein 618 isoform 3
NM_001318042.2 NP_001304971.1 zinc finger protein 618 isoform 4
NM_133374.3 NP_588615.2 zinc finger protein 618 isoform 1
Molecular Function GO Annotation Evidence Referencias Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables transcription coregulator binding IPI
IPI: Inferred from physical interaction
27129234 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in positive regulation of chromatin binding IDA
IDA: Inferred from direct assay
27129234 GOA
Cellular Component GO Annotation Evidence Referencias Source
located in chromatin IDA
IDA: Inferred from direct assay
27129234 GOA
located in pericentric heterochromatin IDA
IDA: Inferred from direct assay
27129234 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF618 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Referencias
Intra
ZNF618 Q5T7W0 UBE2I Homo sapiens Q7KZS0 32296183
Intra
ZNF618 Q5T7W0 UBE2I Homo sapiens Q7KZS0 32296183
Intra
ZNF618 Q5T7W0 UBE2I Homo sapiens Q7KZS0 32296183
Intra
ZNF618 Q5T7W0 G3BP2 Homo sapiens Q9UN86-2 32296183
Intra
ZNF618 Q5T7W0 DPPA3 Homo sapiens Q6W0C5 32296183
Intra
ZNF618 Q5T7W0 TBC1D13 Homo sapiens Q9NVG8 32296183
Intra
ZNF618 Q5T7W0 UBL5 Homo sapiens Q9BZL1 32296183
Intra
ZNF618 Q5T7W0 NTAQ1 Homo sapiens Q96HA8 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction