DPPA3 - developmental pluripotency associated 3 Gene

Also Known as Pgc7; STELLA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 359787

About DPPA3

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,711,433-7,717,559 (from NCBI)

This gene has 1 transcript (splice variant) and 73 orthologues. Low expression observed in reference dataset.

Summary

This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. [provided by RefSeq, Jul 2008]

DPPA3 Products (1)

mRNA Protein Name
NM_199286.4 NP_954980.1 developmental pluripotency-associated protein 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21421998 GOA
located in nucleus IDA
IDA: Inferred from direct assay
21421998 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPPA3 Protein Structure

PGC7_Stella

PGC7_Stella: PGC7/Stella/Dppa3 domain (1 - 154)

  • 0
  • 100
  • 159 a.a.
Protein Preferred Names Protein Names

developmental pluripotency-associated protein 3

  • stella-related protein

DPPA3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DPPA3 Q6W0C5 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
DPPA3 Q6W0C5 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 DEPDC5 Homo sapiens O75140-2
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 DEPDC5 Homo sapiens O75140-2
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 KRT76 Homo sapiens Q01546
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 KRT76 Homo sapiens Q01546
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
Intra
DPPA3 Q6W0C5 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 NUP62 Homo sapiens P37198
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 NUP62 Homo sapiens P37198
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 DYNLL1 Homo sapiens P63167
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 DYNLL1 Homo sapiens P63167
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 HAUS7 Homo sapiens Q99871
Validated Y2H
32296183
Intra
DPPA3 Q6W0C5 HAUS7 Homo sapiens Q99871
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 HAUS7 Homo sapiens Q99871
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 TRIB3 Homo sapiens Q96RU7
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 TRIB3 Homo sapiens Q96RU7
Validated Y2H
32296183
Intra
DPPA3 Q6W0C5 TRIB3 Homo sapiens Q96RU7
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 ZNF618 Homo sapiens Q5T7W0
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 ZNF618 Homo sapiens Q5T7W0
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 DYNLL2 Homo sapiens Q96FJ2
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 DYNLL2 Homo sapiens Q96FJ2
Validated Y2H
32296183
Intra
DPPA3 Q6W0C5 DYNLL2 Homo sapiens Q96FJ2
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 SERTAD3 Homo sapiens Q9UJW9
Y2H Prey Pooling
32296183
Intra
DPPA3 Q6W0C5 SERTAD3 Homo sapiens Q9UJW9
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 SERTAD3 Homo sapiens Q9UJW9
Validated Y2H
32296183
Intra
DPPA3 Q6W0C5 PLEKHG4 Homo sapiens Q58EX7
Y2H Array
32296183
Intra
DPPA3 Q6W0C5 PLEKHG4 Homo sapiens Q58EX7
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Arthrogryposis, Distal, Type 1a

  • Distal Arthrogryposis Type 1

  • Digitotalar Dysmorphism

  • DA1A

  • Da1

  • Amcd1

  • Arthrogryposis, Distal, Type 2b4

  • Distal Arthrogryposis Type 1a

  • Arthrogryposis, Distal, Type 1

  • Arthrogryposis Multiplex Congenita Distal Type 1

  • Arthrogryposis Multiplex Congenita, Distal Type 1

  • Arthrogryposis Multiplex Congenita, Distal, Type I

  • Distal Arthrogryposis Type 1b

  • Arthrogryposis, Distal, 1a

  • Amc

  • Arthrogryposis Multiplex Congenita

  • Arthrogryposis, Distal, 2b4

  • DA2B4

  • Arthrogryposis Multiplex Congenita, Distal, Type 1

  • Arthrogryposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03971 DPPA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DPPA3 RGD RGD:1310932
Mus musculus DPPA3 MGD MGI:1920958
Others DPPA3 NCBI