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54662

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	5-HT Receptor (2) Adrenergic Receptor (1) Biochemical Assay Reagents (1) Drug Derivative (1) EGFR (1) GABA Receptor (2) Isotope-Labeled Compounds (1) Lipoxygenase (1) MicroRNA (12) RXFP Receptor (1) Sodium Channel (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (2) Inflammation/Immunology (1) Neurological Disease (6)
Oligonucleotides:	miRNA mimics (3) miRNA agomirs (3) miRNA antagomirs (3) MicroRNAs (12) miRNA inhibitors (3)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148087

AZD5462 1 Publications Verification	RXFP Receptor	Cardiovascular Disease
AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties .

HY-157786

XPC-5462	Sodium Channel	Neurological Disease
XPC-5462 is a selective Na_V1.6/1.2 inhibitor, with an IC₅₀ of 0.0103 μM against hNa_V1.6, 0.0137 μM against mNa_V1.6, and 0.0109 μM against hNa_V1.2. XPC-5462 significantly reduces epileptiform discharges. XPC-5462 is applicable for epilepsy-related research .

HY-101378

*CGP 54626* hydrochloride** 2 Publications Verification	GABA Receptor	Neurological Disease
CGP 54626 (hydrochloride) is a selective antagonist of GABA_B receptor with an IC₅₀ value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABA_B receptors in neurological signaling .

HY-P1855

*HER2/neu (654-662) GP2*	EGFR	Cancer
HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers .

HY-125641

AL-34662	5-HT Receptor Adrenergic Receptor	Cardiovascular Disease
AL-34662 is a selective 5-HT2A receptoragonist (IC₅₀: 0.77 nM and 1.5 nM for rat and human 5-HT2 receptor). AL-34662 is also a weak α-1D adrenergic agonist activity (EC₅₀:0.4 μM). AL-34662 is an ocular hypotensive agent .

HY-130670

CGP 54626	GABA Receptor	Neurological Disease
CGP 54626 is a GABAB receptor modulator, which is essential in the central and peripheral nervous systems. It is used as a tool to identify and characterize GABAB receptor agonists and antagonists, which will aid in the development of drugs targeting diseases related to these systems. This discovery involves purified GABAB receptors, receptor proteins and their encoding nucleic acids, facilitating the study of new members of the GABAB receptor family through DNA cloning technology and sequence-derived probes .

HY-125641A

*AL-34662* formate**	5-HT Receptor	Neurological Disease
AL-34662 (formate) is a 5-HT₂ receptor agonist (IC₅₀: 0.8-1.5 nM). AL-34662 (formate) stimulates inositol phosphate turnover and Ca ²⁺ release in human ciliary muscle cells (h-CM) (E₅₀: 289 nM) and human trabecular meshwork cells (h-TM) (E₅₀: 254 nM). AL-34662 (formate) can be used in studies to lower intraocular pressure (IOP) .

HY-120410

DL-4662	Biochemical Assay Reagents	Neurological Disease
DL-4662 is a 3,4-dimethoxy derivative that can be identified using techniques such as, GC-EI-MS, LC-tandem mass spectrometry and NMR spectroscopy .

HY-120410A

*DL-4662* hydrochloride**	Drug Derivative	Neurological Disease
DL-4662 hydrochloride is a psychoactive substance .

HY-RI01221

*hsa-miR-4662b inhibitor*	MicroRNA	Cancer
hsa-miR-4662b inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-4662b inhibitor hsa-miR-4662b inhibitor

HY-R01221

*hsa-miR-4662b mimic*	MicroRNA	Cancer
hsa-miR-4662b mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-4662b mimic hsa-miR-4662b mimic

HY-R01220A

*hsa-miR-4662a-5p agomir*	MicroRNA	Cancer
hsa-miR-4662a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4662a-5p agomir hsa-miR-4662a-5p agomir

HY-R01219A

*hsa-miR-4662a-3p agomir*	MicroRNA	Cancer
hsa-miR-4662a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4662a-3p agomir hsa-miR-4662a-3p agomir

HY-R01219

*hsa-miR-4662a-3p mimic*	MicroRNA	Cancer
hsa-miR-4662a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-4662a-3p mimic hsa-miR-4662a-3p mimic

HY-R01220

*hsa-miR-4662a-5p mimic*	MicroRNA	Cancer
hsa-miR-4662a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-4662a-5p mimic hsa-miR-4662a-5p mimic

HY-141909S

4-Fluoroiodobenzene-13C6 NSC 10280-¹³C₆; NSC 4662-¹³C₆; p-Fluoroiodobenzene-¹³C₆	Isotope-Labeled Compounds	Others
4-Fluoroiodobenzene- ¹³C₆ is the ¹³C labeled 4-Fluoroiodobenzene .

HY-19080

SC-45662	Lipoxygenase	Inflammation/Immunology
SC-45662 is a 5-lipoxygenase inhibitor. SC-45662 inhibits the response of monocytes to phytohemagglutinin (PHA). SC-45662 inhibits superoxide production in neutrophils. SC-45662 slows early changes in lung mechanics and pulmonary hypertension in a sheep model of impaired lung function. SC-45662 can be used in research on diseases of the immune system, respiratory system, etc .

HY-RI01221A

*hsa-miR-4662b antagomir*	MicroRNA	Cancer
hsa-miR-4662b antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4662b antagomir hsa-miR-4662b antagomir

HY-R01221A

*hsa-miR-4662b agomir*	MicroRNA	Cancer
hsa-miR-4662b agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4662b agomir hsa-miR-4662b agomir

HY-RI01220

*hsa-miR-4662a-5p inhibitor*	MicroRNA	Cancer
hsa-miR-4662a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-4662a-5p inhibitor hsa-miR-4662a-5p inhibitor

HY-RI01220A

*hsa-miR-4662a-5p antagomir*	MicroRNA	Cancer
hsa-miR-4662a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4662a-5p antagomir hsa-miR-4662a-5p antagomir

HY-RI01219A

*hsa-miR-4662a-3p antagomir*	MicroRNA	Cancer
hsa-miR-4662a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4662a-3p antagomir hsa-miR-4662a-3p antagomir

HY-RI01219

*hsa-miR-4662a-3p inhibitor*	MicroRNA	Cancer
hsa-miR-4662a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-4662a-3p inhibitor hsa-miR-4662a-3p inhibitor

Cat. No.	Product Name	Target	Research Area

HY-P1855

*HER2/neu (654-662) GP2*	EGFR	Cancer
HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers .

4-Fluoroiodobenzene-13C6
4-Fluoroiodobenzene- ¹³C₆ is the ¹³C labeled 4-Fluoroiodobenzene .

Host:	Mouse (4)
Reactivity:	Human (4) Rat (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (3) WB (2) ELISA (3)
Isotype:	IgG1 (1) IgG2b (1)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (3) Monoclonal Antibody (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85970

	p27 KIP 1 Antibody (YA5662)	IHC-P, WB, ICC/IF, ELISA	Human
	p27 KIP 1 Antibody (YA5662) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p27 KIP 1.

HY-P85770

	ERK 1/2 Antibody (YA5462) MAPK1/MAPK3	WB, ICC/IF, ELISA	Human, Mouse, Rat
	ERK 1/2 Antibody (YA5462) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ERK 1/2.

HY-P85774

	NBR1 Antibody (YA5466) Next to BRCA1 gene 1 protein; Cell migration-inducing gene 19 protein; Membrane component chromosome 17 surface marker 2; Neighbor of BRCA1 gene 1 protein; Protein 1A1-3B;	ICC/IF, IHC-P	Human, Mouse, Rat
	NBR1 Antibody (YA5466) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to NBR1.

HY-P84970

	CD162 Antibody (YA4662) CLA; CD162; PSGL1; PSGL-1; PSGL-1; p-selectin glycoprotein ligand-1; CD 162 antibody; CD162 antibody; CD162 antigen antibody; CLA antibody; Cutaneous lymphocyte associated associated antigen antibody; P selectin glycoprotein ligand 1 antibody; P selectin glycoprotein ligand 1 precursor antibody; P-selectin glycoprotein ligand 1 antibody; PSGL 1 antibody; PSGL-1 antibody; PSGL1 antibody; Selectin P ligand antibody; SELPL_HUMAN antibody; SELPLG antibody;	ELISA	Human
	CD162 Antibody (YA4662) is a non-conjugated antibody, targeting to CD162.

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Cat. No.	Product Name		Classification

HY-RI01221

*hsa-miR-4662b inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-4662b inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01221

*hsa-miR-4662b mimic*		MicroRNAs miRNA mimics
hsa-miR-4662b mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01220A

*hsa-miR-4662a-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-4662a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01219A

*hsa-miR-4662a-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-4662a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01219

*hsa-miR-4662a-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-4662a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01220

*hsa-miR-4662a-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-4662a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI01221A

*hsa-miR-4662b antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-4662b antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01221A

*hsa-miR-4662b agomir*		MicroRNAs miRNA agomirs
hsa-miR-4662b agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01220

*hsa-miR-4662a-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-4662a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01220A

*hsa-miR-4662a-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-4662a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01219A

*hsa-miR-4662a-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-4662a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01219

*hsa-miR-4662a-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-4662a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

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