EVI5 - ecotropic viral integration site 5 Gene

Homo sapiens

Also known as NB4S; EVI-5

Gene ID: 7813 | Gene type: protein coding

About EVI5

Cytogenetic location: 1p22.1 Genomic coordinates (GRCh38): 1:92,508,696-92,792,410 (from NCBI)

This gene has 9 transcripts (splice variants), 211 orthologues and 45 paralogues. Ubiquitous expression in testis (RPKM 3.8), placenta (RPKM 3.5) and 25 other tissues.

Summary

Enables GTPase activator activity and small GTPase binding activity. Involved in positive regulation of GTPase activity and retrograde transport, endosome to Golgi. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

EVI5 Products(8)

mRNA	Protein	Name
NM_001308248.2	NP_001295177.1	ecotropic viral integration site 5 protein homolog isoform 1
NM_001350197.2	NP_001337126.1	ecotropic viral integration site 5 protein homolog isoform 3
NM_001350198.2	NP_001337127.1	ecotropic viral integration site 5 protein homolog isoform 4
NM_001377210.1	NP_001364139.1	ecotropic viral integration site 5 protein homolog isoform 5
NM_001377211.1	NP_001364140.1	ecotropic viral integration site 5 protein homolog isoform 6
NM_001377212.1	NP_001364141.1	ecotropic viral integration site 5 protein homolog isoform 7
NM_001377213.1	NP_001364142.1	ecotropic viral integration site 5 protein homolog isoform 8
NM_005665.6	NP_005656.4	ecotropic viral integration site 5 protein homolog isoform 2

EVI5 Protein Structure

RabGAP-TBC

0
200
400
600
810 a.a.

Protein Preferred Names

Protein Names

ecotropic viral integration site 5 protein homolog

dJ846D11.1 (ecotropic viral integration site 5)

Related Diseases

Diseases

Alias

Neuroblastoma

Nb	Neuroblastoma, Susceptibility To
Neuroblastomas	Central Neuroblastoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04576	EVI5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	EVI5	VGNC	VGNC:99919
Bos taurus	EVI5	VGNC	VGNC:55170
Rattus norvegicus	EVI5	RGD	RGD:2322879
Mus musculus	EVI5	MGD	MGI:104736
Felis catus	EVI5	VGNC	VGNC:80209