country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

ARL4A - ADP ribosylation factor like GTPase 4A Gene

Also Known as ARL4

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 10124

About ARL4A

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:12,686,903-12,690,958 (from NCBI)

This gene has 7 transcripts (splice variants), 268 orthologues and 30 paralogues. Broad expression in testis (RPKM 32.8), bone marrow (RPKM 17.5) and 24 other tissues.

Summary

ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ARL4A Products (4)

mRNA	Protein	Name
NM_001037164.3	NP_001032241.1	ADP-ribosylation factor-like protein 4A
NM_001195396.2	NP_001182325.1	ADP-ribosylation factor-like protein 4A
NM_005738.5	NP_005729.1	ADP-ribosylation factor-like protein 4A
NM_212460.4	NP_997625.1	ADP-ribosylation factor-like protein 4A

ARL4A Protein Structure

Arf

0
100
200 a.a.

Protein Preferred Names	Protein Names
ADP-ribosylation factor-like protein 4A	ADP-ribosylation factor-like 4

ARL4A Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ARL4A	P40617	CCDC102B	Homo sapiens	Q68D86	Y2H Array	25416956
Intra	ARL4A	P40617	CCDC102B	Homo sapiens	Q68D86	Y2H Prey Pooling	25416956
Intra	ARL4A	P40617	CCDC102B	Homo sapiens	Q68D86	Validated Y2H	25416956
Intra	ARL4A	P40617	MTUS2	Homo sapiens	Q5JR59-3	Validated Y2H	32296183
Intra	ARL4A	P40617	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	ARL4A	P40617	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	ARL4A	P40617	POF1B	Homo sapiens	Q8WVV4-1	Y2H Prey Pooling	32296183
Intra	ARL4A	P40617	POF1B	Homo sapiens	Q8WVV4-1	Validated Y2H	32296183
Intra	ARL4A	P40617	POF1B	Homo sapiens	Q8WVV4-1	Y2H Array	32296183
Intra	ARL4A	P40617	CCDC57	Homo sapiens	Q2TAC2	Y2H Prey Pooling	25416956
Intra	ARL4A	P40617	CCDC57	Homo sapiens	Q2TAC2	Validated Y2H	25416956
Intra	ARL4A	P40617	SPATC1L	Homo sapiens	Q9H0A9	Y2H Prey Pooling	25416956
Intra	ARL4A	P40617	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	ARL4A	P40617	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	ARL4A	P40617	GOLGA2	Homo sapiens	Q08379	Y2H Array	25416956
Intra	ARL4A	P40617	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	ARL4A	P40617	GOLGA2	Homo sapiens	Q08379	Validated Y2H	32296183
Intra	ARL4A	P40617	KRT19	Homo sapiens	P08727	Y2H Array	32296183
Intra	ARL4A	P40617	KRT19	Homo sapiens	P08727	Y2H Prey Pooling	32296183
Intra	ARL4A	P40617	EVI5	Homo sapiens	O60447	Y2H Prey Pooling	32296183
Intra	ARL4A	P40617	EVI5	Homo sapiens	O60447	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00988	ARL4A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ARL4A	VGNC	VGNC:38112
Macaca mulatta	ARL4A	VGNC	VGNC:84745
Felis catus	ARL4A	VGNC	VGNC:69347
Rattus norvegicus	ARL4A	RGD	RGD:2152
Bos taurus	ARL4A	VGNC	VGNC:26144
Mus musculus	ARL4A	MGD	MGI:99437
Others	ARL4A	NCBI