2. Gene
  3. MED4 - mediator complex subunit 4 Gene

MED4 - mediator complex subunit 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ARC36; VDRIP; DRIP36; TRAP36; HSPC126

Gene ID: 29079 | Gene type: protein coding

About MED4

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:48,075,724-48,095,104 (from NCBI)

This gene has 4 transcripts (splice variants) and 221 orthologues. Ubiquitous expression in testis (RPKM 13.4), bone marrow (RPKM 12.6) and 25 other tissues.

Summary

This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

MED4 Products(2)

mRNA Protein Name
NM_001270629.2 NP_001257558.1 mediator of RNA polymerase II transcription subunit 4 isoform 2
NM_014166.4 NP_054885.1 mediator of RNA polymerase II transcription subunit 4 isoform 1

MED4 Protein Structure

Med4

Med4: Vitamin-D-receptor interacting Mediator subunit 4 (64 - 199)

  • 0
  • 100
  • 200
  • 270 a.a.
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 4

activator-recruited cofactor 36 kDa component

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08303 MED4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MED4 VGNC VGNC:63442
Rattus norvegicus MED4 RGD RGD:1306671
Bos taurus MED4 VGNC VGNC:31368
Canis familiaris MED4 VGNC VGNC:43139
Mus musculus MED4 MGD MGI:1914631
Macaca mulatta MED4 VGNC VGNC:74527
Others MED4 NCBI