TRIM23 - tripartite motif containing 23 Gene

Also Known as ARD1; ARFD1; RNF46

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 373

About TRIM23

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,589,690-65,624,333 (from NCBI)

This gene has 7 transcripts (splice variants), 207 orthologues and 30 paralogues. Ubiquitous expression in brain (RPKM 18.0), prostate (RPKM 7.0) and 24 other tissues.

Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008]

TRIM23 Products (3)

mRNA	Protein	Name
NM_001656.4	NP_001647.1	E3 ubiquitin-protein ligase TRIM23 isoform alpha
NM_033227.3	NP_150230.1	E3 ubiquitin-protein ligase TRIM23 isoform beta
NM_033228.3	NP_150231.1	E3 ubiquitin-protein ligase TRIM23 isoform gamma

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables GDP binding	IDA IDA: Inferred from direct assay	8700863	GOA
enables GTP binding	IDA IDA: Inferred from direct assay	8700863	GOA
enables GTPase activity	IDA IDA: Inferred from direct assay	8700863	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA
enables ubiquitin protein ligase activity	IDA IDA: Inferred from direct assay	28871090	GOA
enables ubiquitin-protein transferase activity	IDA IDA: Inferred from direct assay	15684077	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in positive regulation of autophagy	IDA IDA: Inferred from direct assay	28871090	GOA
involved in protein ubiquitination	IDA IDA: Inferred from direct assay	15684077	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in Golgi membrane	IDA IDA: Inferred from direct assay	9671726	GOA
is active in cytoplasm	IDA IDA: Inferred from direct assay	28871090	GOA
located in lysosomal membrane	IDA IDA: Inferred from direct assay	9671726	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRIM23 Protein Structure

zf-B_box

Arf

0
100
200
300
400
500
574 a.a.

Protein Preferred Names	Protein Names
E3 ubiquitin-protein ligase TRIM23	ADP-ribosylation factor domain protein 1, 64kDa

TRIM23 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TRIM23	P36406	BICRAL	Homo sapiens	Q6AI39	Y2H Array	32296183
Intra	TRIM23	P36406	BICRAL	Homo sapiens	Q6AI39	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	BICRAL	Homo sapiens	Q6AI39	Validated Y2H	32296183
Intra	TRIM23	P36406	TASOR2	Homo sapiens	Q5VWN6-2	Y2H Array	25416956
Intra	TRIM23	P36406	SUMO1P1	Homo sapiens	G2XKQ0	Y2H Array	25416956
Intra	TRIM23	P36406	STK19	Homo sapiens	B7ZLI8	Validated Y2H	25416956
Intra	TRIM23	P36406	FLJ38668	Homo sapiens	C0H5X2	Y2H Array	25416956
Intra	TRIM23	P36406	UBE2I	Homo sapiens	Q7KZS0	Validated Y2H	25416956
Intra	TRIM23	P36406	CREB5	Homo sapiens	Q02930-3	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	IQUB	Homo sapiens	Q8NA54	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	IQUB	Homo sapiens	Q8NA54	Y2H Array	31515488
Intra	TRIM23	P36406	IQUB	Homo sapiens	Q8NA54	Validated Y2H	25416956
Intra	TRIM23	P36406	IQUB	Homo sapiens	Q8NA54	Validated Y2H	32296183
Intra	TRIM23	P36406	TMSB4X	Homo sapiens	Q0P5Q0	Validated Y2H	25416956
Intra	TRIM23	P36406	TRIM29	Homo sapiens	Q0P6H7	Y2H Array	25416956
Intra	TRIM23	P36406	FBF1	Homo sapiens	Q8TES7-6	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	CCDC146	Homo sapiens	Q8IYE0-2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	CCDC146	Homo sapiens	Q8IYE0-2	Validated Y2H	25416956
Intra	TRIM23	P36406	CCDC146	Homo sapiens	Q8IYE0-2	Y2H Array	25416956
Intra	TRIM23	P36406	RNF213	Homo sapiens	Q63HN8-6	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	MTFR2	Homo sapiens	Q6P444	Y2H Array	25416956
Intra	TRIM23	P36406	RSRC2	Homo sapiens	Q7L4I2-2	Validated Y2H	25416956
Intra	TRIM23	P36406	CDC20B	Homo sapiens	Q86Y33	Validated Y2H	25416956
Intra	TRIM23	P36406	RIBC1	Homo sapiens	Q8N443	Validated Y2H	32296183
Intra	TRIM23	P36406	FAM133A	Homo sapiens	Q8N9E0	Validated Y2H	32296183
Intra	TRIM23	P36406	MORN4	Homo sapiens	Q8NDC4	Validated Y2H	25416956
Intra	TRIM23	P36406	MORN4	Homo sapiens	Q8NDC4	Validated Y2H	32296183
Intra	TRIM23	P36406	MORN4	Homo sapiens	Q8NDC4	Y2H Array	25416956
Intra	TRIM23	P36406	ZNF564	Homo sapiens	Q8TBZ8	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	ZNF564	Homo sapiens	Q8TBZ8	Validated Y2H	32296183
Intra	TRIM23	P36406	LGALS14	Homo sapiens	Q8TCE9	Validated Y2H	32296183
Intra	TRIM23	P36406	LINC00526	Homo sapiens	Q96FQ7	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	LINC00526	Homo sapiens	Q96FQ7	Y2H Array	25416956
Intra	TRIM23	P36406	FAM193B	Homo sapiens	Q96PV7-2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	BAG1	Homo sapiens	Q99933	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	BAG1	Homo sapiens	Q99933	Y2H Array	25416956
Intra	TRIM23	P36406	BAG1	Homo sapiens	Q99933	Y2H Array	19060904
Intra	TRIM23	P36406	BAG1	Homo sapiens	Q99933	Validated Y2H	25416956
Intra	TRIM23	P36406	BAG1	Homo sapiens	Q99933	Y2H Pooling	19060904
Intra	TRIM23	P36406	SH2D4A	Homo sapiens	Q9H788-2	Validated Y2H	25416956
Intra	TRIM23	P36406	SH2D4A	Homo sapiens	Q9H788-2	Y2H Array	25416956
Intra	TRIM23	P36406	ARHGEF3	Homo sapiens	Q9NR81	Validated Y2H	25416956
Intra	TRIM23	P36406	ARHGEF3	Homo sapiens	Q9NR81	Y2H Array	25416956
Intra	TRIM23	P36406	ARHGEF3	Homo sapiens	Q9NR81	Y2H Array	29892012
Intra	TRIM23	P36406	ARHGEF3	Homo sapiens	Q9NR81	Y2H Array	31515488
Intra	TRIM23	P36406	MYEF2	Homo sapiens	Q9P2K5-2	Validated Y2H	32296183
Intra	TRIM23	P36406	POLL	Homo sapiens	Q9UGP5-2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	POLL	Homo sapiens	Q9UGP5-2	Validated Y2H	25416956
Intra	TRIM23	P36406	SNAI1	Homo sapiens	O95863	Y2H Array	25416956
Intra	TRIM23	P36406	SNAI1	Homo sapiens	O95863	Validated Y2H	25416956
Intra	TRIM23	P36406	SNAI1	Homo sapiens	O95863	Y2H Array	31515488
Intra	TRIM23	P36406	LAGE3	Homo sapiens	Q14657	Validated Y2H	32296183
Intra	TRIM23	P36406	COX5B	Homo sapiens	P10606	Y2H Array	31515488
Intra	TRIM23	P36406	COX5B	Homo sapiens	P10606	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	COX5B	Homo sapiens	P10606	Y2H Array	25416956
Intra	TRIM23	P36406	MSRB3	Homo sapiens	Q8IXL7-2	Validated Y2H	32296183
Intra	TRIM23	P36406	CCDC13	Homo sapiens	Q8IYE1	Validated Y2H	32296183
Intra	TRIM23	P36406	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	TRIM23	P36406	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	TRIM23	P36406	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	TRIM23	P36406	TEPSIN	Homo sapiens	Q96N21	Validated Y2H	32296183
Intra	TRIM23	P36406	FLAD1	Homo sapiens	Q8NFF5-2	Validated Y2H	32296183
Intra	TRIM23	P36406	ATPAF2	Homo sapiens	Q8N5M1	Y2H Array	31515488
Intra	TRIM23	P36406	ATPAF2	Homo sapiens	Q8N5M1	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	ATPAF2	Homo sapiens	Q8N5M1	Validated Y2H	25416956
Intra	TRIM23	P36406	ATPAF2	Homo sapiens	Q8N5M1	Y2H Array	25416956
Intra	TRIM23	P36406	LMO3	Homo sapiens	Q8TAP4-4	Validated Y2H	32296183
Intra	TRIM23	P36406	NEDD9	Homo sapiens	Q14511-2	Validated Y2H	32296183
Intra	TRIM23	P36406	CDR2	Homo sapiens	Q01850	Validated Y2H	32296183
Intra	TRIM23	P36406	CDR2	Homo sapiens	Q01850	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	CDR2	Homo sapiens	Q01850	Y2H Array	32296183
Intra	TRIM23	P36406	TCEANC	Homo sapiens	Q8N8B7-2	Validated Y2H	32296183
Intra	TRIM23	P36406	POM121	Homo sapiens	Q96HA1-2	Validated Y2H	32296183
Intra	TRIM23	P36406	HAPLN2	Homo sapiens	Q9GZV7	Validated Y2H	32296183
Intra	TRIM23	P36406	VGLL1	Homo sapiens	Q99990	Validated Y2H	32296183
Intra	TRIM23	P36406	VGLL1	Homo sapiens	Q99990	Y2H Array	32296183
Intra	TRIM23	P36406	VGLL1	Homo sapiens	Q99990	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	MYOM1	Homo sapiens	P52179-2	Validated Y2H	32296183
Intra	TRIM23	P36406	CPNE7	Homo sapiens	Q9UBL6-2	Validated Y2H	32296183
Intra	TRIM23	P36406	NOXA1	Homo sapiens	Q86UR1-2	Validated Y2H	32296183
Intra	TRIM23	P36406	GGA3	Homo sapiens	Q9NZ52-2	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	GGA3	Homo sapiens	Q9NZ52-2	Y2H Array	32296183
Intra	TRIM23	P36406	GGA3	Homo sapiens	Q9NZ52-2	Validated Y2H	32296183
Intra	TRIM23	P36406	EPN2	Homo sapiens	O95208-2	Y2H Array	32296183
Intra	TRIM23	P36406	EPN2	Homo sapiens	O95208-2	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	RUFY1	Homo sapiens	Q96T51-2	Validated Y2H	32296183
Intra	TRIM23	P36406	EAF2	Homo sapiens	Q96CJ1	Validated Y2H	25416956
Intra	TRIM23	P36406	FAM83A	Homo sapiens	Q86UY5	Y2H Array	25416956
Intra	TRIM23	P36406	ZC2HC1C	Homo sapiens	Q53FD0-2	Validated Y2H	32296183
Intra	TRIM23	P36406	ZC2HC1C	Homo sapiens	Q53FD0-2	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	ZC2HC1C	Homo sapiens	Q53FD0-2	Y2H Array	32296183
Intra	TRIM23	P36406	ANKRD55	Homo sapiens	Q3KP44	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	ANKRD55	Homo sapiens	Q3KP44	Validated Y2H	32296183
Intra	TRIM23	P36406	ANKRD55	Homo sapiens	Q3KP44	Y2H Array	32296183
Intra	TRIM23	P36406	PRPF31	Homo sapiens	Q8WWY3	Validated Y2H	32296183
Intra	TRIM23	P36406	IL16	Homo sapiens	Q14005-2	Validated Y2H	32296183
Intra	TRIM23	P36406	ZNF474	Homo sapiens	Q6S9Z5	Y2H Array	32296183
Intra	TRIM23	P36406	ZNF474	Homo sapiens	Q6S9Z5	Validated Y2H	32296183
Intra	TRIM23	P36406	ZNF474	Homo sapiens	Q6S9Z5	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	FAM110A	Homo sapiens	Q9BQ89	Validated Y2H	25416956
Intra	TRIM23	P36406	FAM110A	Homo sapiens	Q9BQ89	Validated Y2H	32296183
Intra	TRIM23	P36406	KIFC3	Homo sapiens	Q9BVG8	Validated Y2H	25416956
Intra	TRIM23	P36406	KIFC3	Homo sapiens	Q9BVG8	Y2H Array	25416956
Intra	TRIM23	P36406	LAMP2	Homo sapiens	P13473-2	Y2H Array	32814053
Intra	TRIM23	P36406	LAMP2	Homo sapiens	P13473-2	Validated Y2H	32814053
Intra	TRIM23	P36406	LAMP2	Homo sapiens	P13473-2	Y2H Pooling	32814053
Intra	TRIM23	P36406	EHHADH	Homo sapiens	Q08426	Validated Y2H	32296183
Intra	TRIM23	P36406	TRIM55	Homo sapiens	Q9BYV6	Anti Tag CoIP	22493164
Intra	TRIM23	P36406	TROAP	Homo sapiens	Q12815	Y2H Pooling	19060904
Intra	TRIM23	P36406	TROAP	Homo sapiens	Q12815	Y2H Array	19060904
Intra	TRIM23	P36406	TROAP	Homo sapiens	Q12815	Y2H Array	25416956
Intra	TRIM23	P36406	TROAP	Homo sapiens	Q12815	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	AP3M1	Homo sapiens	Q9Y2T2	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	AP3M1	Homo sapiens	Q9Y2T2	Validated Y2H	32296183
Intra	TRIM23	P36406	JOSD1	Homo sapiens	Q15040	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	JOSD1	Homo sapiens	Q15040	Validated Y2H	25416956
Intra	TRIM23	P36406	USP20	Homo sapiens	Q9Y2K6	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	MRPL45	Homo sapiens	Q9BRJ2	Y2H Array	25416956
Intra	TRIM23	P36406	MRPL45	Homo sapiens	Q9BRJ2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	HAUS1	Homo sapiens	Q96CS2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	HAUS1	Homo sapiens	Q96CS2	Y2H Array	25416956
Intra	TRIM23	P36406	PPP1R18	Homo sapiens	Q6NYC8	Validated Y2H	25416956
Intra	TRIM23	P36406	PPP1R18	Homo sapiens	Q6NYC8	Y2H Array	25416956
Intra	TRIM23	P36406	TSEN54	Homo sapiens	Q7Z6J9	Validated Y2H	32296183
Intra	TRIM23	P36406	ZBTB4	Homo sapiens	Q9P1Z0	Validated Y2H	32296183
Intra	TRIM23	P36406	CXCL14	Homo sapiens	O95715	Validated Y2H	25416956
Intra	TRIM23	P36406	PRPF18	Homo sapiens	Q99633	Validated Y2H	32296183
Intra	TRIM23	P36406	GATA2	Homo sapiens	P23769	Y2H Array	31515488
Intra	TRIM23	P36406	GATA2	Homo sapiens	P23769	Y2H Array	25416956
Intra	TRIM23	P36406	PPP1R15B	Homo sapiens	Q5SWA1	Validated Y2H	32296183
Intra	TRIM23	P36406	TXNDC5	Homo sapiens	Q86UY0	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	TXNDC5	Homo sapiens	Q86UY0	Validated Y2H	25416956
Intra	TRIM23	P36406	RAN	Homo sapiens	P62826	Validated Y2H	32814053
Intra	TRIM23	P36406	RAN	Homo sapiens	P62826	Y2H Array	32814053
Intra	TRIM23	P36406	RAN	Homo sapiens	P62826	Y2H Pooling	32814053
Intra	TRIM23	P36406	SMG9	Homo sapiens	Q9H0W8	Validated Y2H	25416956
Intra	TRIM23	P36406	SMG9	Homo sapiens	Q9H0W8	Validated Y2H	32296183
Intra	TRIM23	P36406	SMG9	Homo sapiens	Q9H0W8	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	KRT75	Homo sapiens	O95678	Y2H Array	32296183
Intra	TRIM23	P36406	KRT75	Homo sapiens	O95678	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	KRT76	Homo sapiens	Q01546	Validated Y2H	32296183
Intra	TRIM23	P36406	CSRP2	Homo sapiens	Q16527	Validated Y2H	32296183
Intra	TRIM23	P36406	ZNF408	Homo sapiens	Q9H9D4	Validated Y2H	32296183
Intra	TRIM23	P36406	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	TRIM23	P36406	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	TRIM23	P36406	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	TRIM23	P36406	PIAS2	Homo sapiens	O75928	Y2H Array	25416956
Intra	TRIM23	P36406	HRAS	Homo sapiens	P01112	Y2H Array	32814053
Intra	TRIM23	P36406	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
Intra	TRIM23	P36406	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
Intra	TRIM23	P36406	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	TRIM23	P36406	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	TRIM23	P36406	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	TRIM23	P36406	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
Intra	TRIM23	P36406	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
Intra	TRIM23	P36406	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
Intra	TRIM23	P36406	SLC25A6	Homo sapiens	P12236	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	SLC25A6	Homo sapiens	P12236	Y2H Array	25416956
Intra	TRIM23	P36406	TRAF1	Homo sapiens	Q13077	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	PSMA1	Homo sapiens	P25786	Y2H Array	19060904
Intra	TRIM23	P36406	PSMA1	Homo sapiens	P25786	Y2H Pooling	19060904
Intra	TRIM23	P36406	SNRPB	Homo sapiens	P14678-2	Validated Y2H	25416956
Intra	TRIM23	P36406	SNRPB	Homo sapiens	P14678-2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	SNRPB	Homo sapiens	P14678-2	Y2H Array	25416956
Intra	TRIM23	P36406	TARDBP	Homo sapiens	Q13148	Y2H Array	32814053
Intra	TRIM23	P36406	TARDBP	Homo sapiens	Q13148	Y2H Pooling	32814053
Intra	TRIM23	P36406	TARDBP	Homo sapiens	Q13148	Validated Y2H	32814053
Intra	TRIM23	P36406	HOXB5	Homo sapiens	P09067	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	HOXB5	Homo sapiens	P09067	Validated Y2H	25416956
Intra	TRIM23	P36406	ZFAND2A	Homo sapiens	Q8N6M9	Validated Y2H	32296183
Intra	TRIM23	P36406	KAT5	Homo sapiens	Q92993	Validated Y2H	25416956
Intra	TRIM23	P36406	PLEKHA2	Homo sapiens	Q9HB19	Validated Y2H	32296183
Intra	TRIM23	P36406	DOCK2	Homo sapiens	Q92608	Y2H Array	25416956
Intra	TRIM23	P36406	HIP1	Homo sapiens	O00291	Y2H Array	32814053
Intra	TRIM23	P36406	HIP1	Homo sapiens	O00291	Validated Y2H	32814053
Intra	TRIM23	P36406	HIP1	Homo sapiens	O00291	Y2H Pooling	32814053
Intra	TRIM23	P36406	TNFAIP3	Homo sapiens	P21580	Validated Y2H	25416956
Intra	TRIM23	P36406	PHF1	Homo sapiens	O43189	Y2H Array	31515488
Intra	TRIM23	P36406	CWF19L2	Homo sapiens	Q2TBE0	Validated Y2H	32296183
Intra	TRIM23	P36406	UTP23	Homo sapiens	Q9BRU9	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	UTP23	Homo sapiens	Q9BRU9	Validated Y2H	25416956
Intra	TRIM23	P36406	ZNF835	Homo sapiens	Q9Y2P0	Validated Y2H	32296183
Intra	TRIM23	P36406	SNW1	Homo sapiens	Q13573	Y2H Array	32296183
Intra	TRIM23	P36406	SNW1	Homo sapiens	Q13573	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	SNW1	Homo sapiens	Q13573	Validated Y2H	32296183
Intra	TRIM23	P36406	ZNF587	Homo sapiens	Q96SQ5	Validated Y2H	32296183
Intra	TRIM23	P36406	FAM90A1	Homo sapiens	Q86YD7	Validated Y2H	32296183
Intra	TRIM23	P36406	FAM90A1	Homo sapiens	Q86YD7	Y2H Array	25416956
Intra	TRIM23	P36406	FAM90A1	Homo sapiens	Q86YD7	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	KRT6A	Homo sapiens	P02538	Y2H Array	25416956
Intra	TRIM23	P36406	KRT6A	Homo sapiens	P02538	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	TRIM29	Homo sapiens	Q14134	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	TRIM29	Homo sapiens	Q14134	Y2H Array	31515488
Intra	TRIM23	P36406	TCEA2	Homo sapiens	Q15560	Validated Y2H	32296183
Intra	TRIM23	P36406	ZBTB16	Homo sapiens	Q05516	Validated Y2H	32296183
Intra	TRIM23	P36406	CBX8	Homo sapiens	Q9HC52	Validated Y2H	32296183
Intra	TRIM23	P36406	C8orf33	Homo sapiens	Q9H7E9	Validated Y2H	25416956
Intra	TRIM23	P36406	ARFGAP1	Homo sapiens	Q8N6T3	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	ARFGAP1	Homo sapiens	Q8N6T3	Y2H Array	25416956
Intra	TRIM23	P36406	ZNF20	Homo sapiens	P17024	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	CASP6	Homo sapiens	P55212	Validated Y2H	32814053
Intra	TRIM23	P36406	CASP6	Homo sapiens	P55212	Y2H Array	32814053
Intra	TRIM23	P36406	CASP6	Homo sapiens	P55212	Y2H Pooling	32814053
Intra	TRIM23	P36406	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	TRIM23	P36406	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	TRIM23	P36406	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	TRIM23	P36406	MRPL4	Homo sapiens	Q9BYD3	Y2H Array	25416956
Intra	TRIM23	P36406	MRPL4	Homo sapiens	Q9BYD3	Validated Y2H	25416956
Intra	TRIM23	P36406	NFU1	Homo sapiens	Q9UMS0	Validated Y2H	25416956
Intra	TRIM23	P36406	NFU1	Homo sapiens	Q9UMS0	Y2H Array	25416956
Intra	TRIM23	P36406	PKP4	Homo sapiens	Q99569	Y2H Array	25416956
Intra	TRIM23	P36406	LENG1	Homo sapiens	Q96BZ8	Validated Y2H	32296183
Intra	TRIM23	P36406	HSPB7	Homo sapiens	Q9UBY9	Validated Y2H	25416956
Intra	TRIM23	P36406	LMO2	Homo sapiens	P25791	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	LMO2	Homo sapiens	P25791	Y2H Array	25416956
Intra	TRIM23	P36406	LNX1	Homo sapiens	Q8TBB1	Y2H Array	29892012
Intra	TRIM23	P36406	LNX1	Homo sapiens	Q8TBB1	Y2H Pooling	16189514
Intra	TRIM23	P36406	LNX1	Homo sapiens	Q8TBB1	Y2H Array	31515488
Intra	TRIM23	P36406	C2CD6	Homo sapiens	Q53TS8	Validated Y2H	32296183
Intra	TRIM23	P36406	KLHL42	Homo sapiens	Q9P2K6	Validated Y2H	32296183
Intra	TRIM23	P36406	LGALS8	Homo sapiens	O00214	Y2H Array	25416956
Intra	TRIM23	P36406	LGALS8	Homo sapiens	O00214	Y2H Array	29892012
Intra	TRIM23	P36406	TRIM23	Homo sapiens	P36406	Y2H Pooling	16189514
Intra	TRIM23	P36406	GEM	Homo sapiens	P55040	Validated Y2H	32296183
Intra	TRIM23	P36406	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	31515488
Intra	TRIM23	P36406	ZNF581	Homo sapiens	Q9P0T4	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	GEM	Homo sapiens	P55040	Y2H Pooling	19060904
Intra	TRIM23	P36406	TBC1D22B	Homo sapiens	Q9NU19	Y2H Array	31515488
Intra	TRIM23	P36406	TRIM23	Homo sapiens	P36406	Anti Tag CoIP	22493164
Intra	TRIM23	P36406	GEM	Homo sapiens	P55040	Y2H Pooling	16189514
Intra	TRIM23	P36406	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	32296183
Intra	TRIM23	P36406	TBC1D22B	Homo sapiens	Q9NU19	Validated Y2H	25416956
Intra	TRIM23	P36406	TBC1D22B	Homo sapiens	Q9NU19	Validated Y2H	32296183
Intra	TRIM23	P36406	TBC1D22B	Homo sapiens	Q9NU19	Y2H Array	25416956
Intra	TRIM23	P36406	GEM	Homo sapiens	P55040	Y2H Array	31515488
Intra	TRIM23	P36406	ZNF581	Homo sapiens	Q9P0T4	Y2H Pooling	16189514
Intra	TRIM23	P36406	TBC1D22B	Homo sapiens	Q9NU19	Y2H Array	29892012
Intra	TRIM23	P36406	GEM	Homo sapiens	P55040	Y2H Array	19060904
Intra	TRIM23	P36406	NEK6	Homo sapiens	Q9HC98	Y2H Array	25416956
Intra	TRIM23	P36406	NEK6	Homo sapiens	Q9HC98	Y2H Array	29892012
Intra	TRIM23	P36406	NEK6	Homo sapiens	Q9HC98	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	NEK6	Homo sapiens	Q9HC98	Validated Y2H	25416956
Intra	TRIM23	P36406	ZNF417	Homo sapiens	Q8TAU3	Validated Y2H	32296183
Intra	TRIM23	P36406	ZC2HC1C	Homo sapiens	Q53FD0	Validated Y2H	25416956
Intra	TRIM23	P36406	ZC2HC1C	Homo sapiens	Q53FD0	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183
Intra	TRIM23	P36406	BRME1	Homo sapiens	Q0VDD7	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	BRME1	Homo sapiens	Q0VDD7	Y2H Pooling	16189514
Intra	TRIM23	P36406	SORBS3	Homo sapiens	O60504	Y2H Array	32296183
Intra	TRIM23	P36406	SORBS3	Homo sapiens	O60504	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	SORBS3	Homo sapiens	O60504	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	UBQLN1	Homo sapiens	Q9UMX0	Y2H Pooling	32814053
Intra	TRIM23	P36406	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32296183
Intra	TRIM23	P36406	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32814053
Intra	TRIM23	P36406	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	32814053
Intra	TRIM23	P36406	SPG21	Homo sapiens	Q9NZD8	Validated Y2H	25416956
Intra	TRIM23	P36406	SPG21	Homo sapiens	Q9NZD8	Y2H Array	25416956
Intra	TRIM23	P36406	RAMAC	Homo sapiens	Q9BTL3	Validated Y2H	25416956
Intra	TRIM23	P36406	RAMAC	Homo sapiens	Q9BTL3	Validated Y2H	32296183
Intra	TRIM23	P36406	RAMAC	Homo sapiens	Q9BTL3	Y2H Array	25416956
Intra	TRIM23	P36406	ENKD1	Homo sapiens	Q9H0I2	Validated Y2H	32296183
Intra	TRIM23	P36406	MYOZ1	Homo sapiens	Q9NP98	Validated Y2H	32296183
Intra	TRIM23	P36406	WDR25	Homo sapiens	Q64LD2	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	WDR25	Homo sapiens	Q64LD2	Validated Y2H	25416956
Intra	TRIM23	P36406	WDR25	Homo sapiens	Q64LD2	Y2H Array	25416956
Intra	TRIM23	P36406	ANKRD36BP1	Homo sapiens	Q96IX9	Validated Y2H	25416956
Intra	TRIM23	P36406	AQP1	Homo sapiens	P29972	Y2H Array	25416956
Intra	TRIM23	P36406	AQP1	Homo sapiens	P29972	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	AQP1	Homo sapiens	P29972	Validated Y2H	25416956
Intra	TRIM23	P36406	GMCL2	Homo sapiens	Q8NEA9	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	GPKOW	Homo sapiens	Q92917	Y2H Array	31515488
Intra	TRIM23	P36406	GPKOW	Homo sapiens	Q92917	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	SH2D4A	Homo sapiens	Q9H788	Validated Y2H	25416956
Intra	TRIM23	P36406	SH2D4A	Homo sapiens	Q9H788	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	SIAH1	Homo sapiens	Q8IUQ4	Validated Y2H	25416956
Intra	TRIM23	P36406	SIAH1	Homo sapiens	Q8IUQ4	Y2H Array	25416956
Intra	TRIM23	P36406	SIAH1	Homo sapiens	Q8IUQ4	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	TACO1	Homo sapiens	Q9BSH4	Validated Y2H	32296183
Intra	TRIM23	P36406	PITX1	Homo sapiens	P78337	Validated Y2H	32296183
Intra	TRIM23	P36406	SCNM1	Homo sapiens	Q9BWG6	Validated Y2H	32296183
Intra	TRIM23	P36406	CARD9	Homo sapiens	Q9H257	Y2H Array	31515488
Intra	TRIM23	P36406	CARD9	Homo sapiens	Q9H257	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	CARD9	Homo sapiens	Q9H257	Y2H Array	25416956
Intra	TRIM23	P36406	CARD9	Homo sapiens	Q9H257	Validated Y2H	25416956
Intra	TRIM23	P36406	GPANK1	Homo sapiens	O95872	Y2H Array	31515488
Intra	TRIM23	P36406	GPANK1	Homo sapiens	O95872	Validated Y2H	25416956
Intra	TRIM23	P36406	GPANK1	Homo sapiens	O95872	Y2H Array	25416956
Intra	TRIM23	P36406	NXT2	Homo sapiens	Q9NPJ8	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	PPIL2	Homo sapiens	Q13356	Validated Y2H	25416956
Intra	TRIM23	P36406	NAB2	Homo sapiens	Q15742	Validated Y2H	32296183
Intra	TRIM23	P36406	DCX	Homo sapiens	O43602	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	TSHZ3	Homo sapiens	Q63HK5	Y2H Array	25416956
Intra	TRIM23	P36406	RCAN3	Homo sapiens	Q9UKA8	Validated Y2H	32296183
Intra	TRIM23	P36406	RCAN3	Homo sapiens	Q9UKA8	Y2H Prey Pooling	32296183
Intra	TRIM23	P36406	CDC73	Homo sapiens	Q6P1J9	Validated Y2H	32296183
Intra	TRIM23	P36406	DMC1	Homo sapiens	Q14565	Y2H Array	25416956
Intra	TRIM23	P36406	DMC1	Homo sapiens	Q14565	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	ATXN1	Homo sapiens	P54253	Y2H Array	32814053
Intra	TRIM23	P36406	ATXN1	Homo sapiens	P54253	Validated Y2H	32814053
Intra	TRIM23	P36406	ATXN1	Homo sapiens	P54253	Y2H Pooling	32814053
Intra	TRIM23	P36406	SNAI2	Homo sapiens	O43623	Y2H Prey Pooling	25416956
Intra	TRIM23	P36406	SNAI2	Homo sapiens	O43623	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

TRIM23 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82524	TRIM23 Antibody (YA2269)	WB	Human, Mouse, Rat
HY-P82524A	TRIM23 Antibody (YA2269)(PBS only)	WB	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Immunodeficiency 33	IMD33 X-Linked Mendelian Susceptibility To Mycobacterial Diseases Due To Ikbkg Deficiency X-Linked Mendelian Susceptibility To Mycobacterial Diseases Due To Nemo Deficiency X-Linked Msmd Due To Ikbkg Deficiency X-Linked Msmd Due To Nemo Deficiency Invasive Pneumococcal Disease, Recurrent Isolated, 2 Invasive Pneumococcal Disease, Recurrent Isolated, 2, Formerly Ipd2, Formerly Nf-Kappa B Essential Modulator Deficiency Familial X-Linked 1 Atypical Mycobacteriosis Nemo Deficiency Syndrome Amcbx1 Familial, X-Linked, Atypical Mycobacteriosis 1 Ipd2 Recurrent Isolated Invasive Pneumococcal Disease 2 X-Linked Disseminated Atypical Mycobacterial Infection Type 1 X-Linked Immunodeficiency 33, Mycobacteriosis X-Linked Susceptibility To Mycobacterial Disease Type 1 Invasive Pneumococcal Disease, Recurrent Isolated, Type 2 Atypical Mycobacteriosis, Familial, X-Linked 1
Mulibrey Nanism	MUL Muscle-Liver-Brain-Eye Nanism Pericardial Constriction And Growth Failure Perheentupa Syndrome Mulibrey Growth Disorder Mulibrey Nanism Syndrome Pericardial Constriction With Growth Failure Nanism Mulibrey

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15028	TRIM23 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20609	Trim23 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27117	Trim23 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TRIM23	VGNC	VGNC:36320
Macaca mulatta	TRIM23	VGNC	VGNC:79962
Mus musculus	TRIM23	MGD	MGI:1933161
Canis familiaris	TRIM23	VGNC	VGNC:47809
Rattus norvegicus	TRIM23	RGD	RGD:621587
Felis catus	TRIM23	VGNC	VGNC:68048
Others	TRIM23	NCBI