TNFAIP3 - TNF alpha induced protein 3 Gene

Also Known as A20; AISBL; AIFBL1; OTUD7C; TNFA1P2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7128

About TNFAIP3

Cytogenetic location: 6q23.3 Genomic coordinates (GRCh38): 6:137,866,349-137,883,312 (from NCBI)

This gene has 8 transcripts (splice variants), 204 orthologues, 2 paralogues and is associated with 99 phenotypes. Broad expression in bone marrow (RPKM 156.2), appendix (RPKM 61.9) and 14 other tissues.

Summary

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a Zinc Finger Protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated Apoptosis. The encoded protein, which has both ubiquitin Ligase and Deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]

TNFAIP3 Products (3)

mRNA Protein Name
NM_001270507.2 NP_001257436.1 tumor necrosis factor alpha-induced protein 3
NM_001270508.2 NP_001257437.1 tumor necrosis factor alpha-induced protein 3
NM_006290.4 NP_006281.1 tumor necrosis factor alpha-induced protein 3
Molecular Function GO Annotation Evidence References Source
enables K63-linked deubiquitinase activity EXP
EXP: Inferred from Experiment
14748687 GOA
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
15258597 GOA
enables cysteine-type deubiquitinase activity IMP
IMP: Inferred from mutant phenotype
15258597 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables protease binding IPI
IPI: Inferred from physical interaction
18223652 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9299557 GOA
enables ubiquitin binding IPI
IPI: Inferred from physical interaction
19285159 GOA
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
15258597 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
19912257 GOA
involved in negative regulation of CD40 signaling pathway IMP
IMP: Inferred from mutant phenotype
12885753 GOA
involved in negative regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
18223652 GOA
involved in negative regulation of canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
11463333 GOA
involved in negative regulation of endothelial cell apoptotic process IDA
IDA: Inferred from direct assay
12885753 GOA
involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IDA
IDA: Inferred from direct assay
12167698 GOA
acts upstream of or within negative regulation of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
28094437 GOA
involved in negative regulation of interleukin-2 production IMP
IMP: Inferred from mutant phenotype
18223652 GOA
involved in negative regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
20392859 GOA
involved in negative regulation of smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
16816117 GOA
involved in negative regulation of toll-like receptor 3 signaling pathway IDA
IDA: Inferred from direct assay
15474016 GOA
involved in positive regulation of protein catabolic process IDA
IDA: Inferred from direct assay
21127049 GOA
involved in protein K11-linked deubiquitination IDA
IDA: Inferred from direct assay
23827681 GOA
involved in protein K48-linked deubiquitination IDA
IDA: Inferred from direct assay
23827681 GOA
involved in protein K48-linked ubiquitination IDA
IDA: Inferred from direct assay
15258597 GOA
involved in protein K63-linked deubiquitination IDA
IDA: Inferred from direct assay
15258597 GOA
involved in response to molecule of bacterial origin IDA
IDA: Inferred from direct assay
19912257 GOA
involved in tolerance induction to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
21220427 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11463333 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TNFAIP3 Protein Structure

OTU

OTU: OTU-like cysteine protease (98 - 257)

zf-A20

zf-A20: A20-like zinc finger (385 - 408)

zf-A20

zf-A20: A20-like zinc finger (475 - 500)

zf-A20

zf-A20: A20-like zinc finger (605 - 628)

zf-A20

zf-A20: A20-like zinc finger (655 - 678)

zf-A20

zf-A20: A20-like zinc finger (714 - 738)

zf-A20

zf-A20: A20-like zinc finger (759 - 784)

  • 0
  • 200
  • 400
  • 600
  • 790 a.a.
Protein Preferred Names Protein Names

tumor necrosis factor alpha-induced protein 3

  • OTU domain-containing protein 7C

TNFAIP3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TNFAIP3 P21580 PIBF1 Homo sapiens Q4G0R1 32296183
Intra
TNFAIP3 P21580 ARRDC3 Homo sapiens Q96B67 25416956
Intra
TNFAIP3 P21580 ARRDC3 Homo sapiens Q96B67 32296183
Intra
TNFAIP3 P21580 ARRDC3 Homo sapiens Q96B67 25416956
Intra
TNFAIP3 P21580 ARRDC3 Homo sapiens Q96B67 25416956
Intra
TNFAIP3 P21580 TRAF2 Homo sapiens Q12933 31515488
Intra
TNFAIP3 P21580 TRAF2 Homo sapiens Q12933 25416956
Intra
TNFAIP3 P21580 TRAF2 Homo sapiens Q12933 32296183
Intra
TNFAIP3 P21580 TRAF2 Homo sapiens Q12933 32296183
Intra
TNFAIP3 P21580 TRAF2 Homo sapiens Q12933 32296183
Intra
TNFAIP3 P21580 TRAF2 Homo sapiens Q12933 30561431
Intra
TNFAIP3 P21580 YWHAE Homo sapiens P62258
Y2H
21988832
Intra
TNFAIP3 P21580 YWHAE Homo sapiens P62258 36931259
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 32296183
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 30561431
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 32296183
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 32296183
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 25416956
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 31515488
Intra
TNFAIP3 P21580 TNIP1 Homo sapiens Q15025 25416956
Intra
TNFAIP3 P21580 TNIP2 Homo sapiens Q8NFZ5 30561431
Intra
TNFAIP3 P21580 YWHAG Homo sapiens P61981
SLC
36931259
Intra
TNFAIP3 P21580 RNF11 Homo sapiens Q9Y3C5
Y2H
15231748
Cross
TNFAIP3 P21580 Ywhah Mus musculus P68510
Y2H
9299557
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 32296183
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 25416956
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 25502805
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 32296183
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 30561431
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 31515488
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 11389905
Intra
TNFAIP3 P21580 TNFAIP3 Homo sapiens P21580 32296183
Intra
TNFAIP3 P21580 TAX1BP1 Homo sapiens Q86VP1 32296183
Intra
TNFAIP3 P21580 TAX1BP1 Homo sapiens Q86VP1 32296183
Intra
TNFAIP3 P21580 TAX1BP1 Homo sapiens Q86VP1 30561431
Intra
TNFAIP3 P21580 TAX1BP1 Homo sapiens Q86VP1 11389905
Intra
TNFAIP3 P21580 TAX1BP1 Homo sapiens Q86VP1 33961781
Intra
TNFAIP3 P21580 TAX1BP1 Homo sapiens Q86VP1 32296183
Intra
TNFAIP3 P21580 RNF216 Homo sapiens Q9NWF9 32296183
Intra
TNFAIP3 P21580 RNF216 Homo sapiens Q9NWF9 32296183
Intra
TNFAIP3 P21580 RNF216 Homo sapiens Q9NWF9 32296183
Intra
TNFAIP3 P21580 LNX1 Homo sapiens Q8TBB1 32296183
Intra
TNFAIP3 P21580 TRIM23 Homo sapiens P36406 25416956
Intra
TNFAIP3 P21580 TRIM23 Homo sapiens P36406 32296183
Intra
TNFAIP3 P21580 TRIM23 Homo sapiens P36406 32296183
Intra
TNFAIP3 P21580 TRIM23 Homo sapiens P36406 25416956
Intra
TNFAIP3 P21580 TRIM23 Homo sapiens P36406 32296183
Intra
TNFAIP3 P21580 RAD23A Homo sapiens P54725 32296183
Intra
TNFAIP3 P21580 CASP8 Homo sapiens Q14790 19060883
Intra
TNFAIP3 P21580 IKBKG Homo sapiens Q9Y6K9
Y2H
21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

TNFAIP3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82486 TNFAIP3 Antibody (YA2231) WB, IHC-F, IHC-P, ICC/IF Human
HY-P82486A TNFAIP3 Antibody (YA2231)(PBS only) WB, IHC-F, IHC-P, ICC/IF Human

Related Diseases

Diseases Alias
Autoinflammatory Syndrome, Familial, Behcet-Like 1
  • AIFBL1

  • Aifbl

  • Hereditary Pediatric Behcet-Like Disease

  • Behcet-Like Disease Due To Ha20

  • Behcet-Like Disease Due To Haploinsufficiency Of A20

Familial Behcet-Like Autoinflammatory Syndrome
  • Autoinflammatory Syndrome, Familial, Behcet-Like

  • A20 Haploinsufficiency

Iridocyclitis
  • Primary Iridocyclitis

Systemic Lupus Erythematosus
  • Lupus Nephritis

  • SLE

  • Disseminated Lupus Erythematosus

  • Systemic Lupus Erythematosus, Susceptibility To

  • Lupus Erythematosus, Systemic

  • Lupus Nephritis, Susceptibility To

  • Libman-Sacks Disease

  • Systemic Lupus Erythematosus Susceptibility To

  • Sle - Lupus Erythematosus, Systemic

  • Le Syndrome

  • Lupus

  • Lupus Erythematosus Systemic

  • Lupus Erythematosus, Systemic, Susceptibility To

  • Lupus Vulgaris

  • Lupus Erythematosus, Discoid

  • Lupus Erythematosus

  • Systemic Lupus Erythematosus Nos

  • Sle - [Systemic Lupus Erythematosus]

Autoimmune Lymphoproliferative Syndrome
  • ALPS

  • Canale-Smith Syndrome

  • Autoimmune Lymphoproliferative Syndrome, Type Ia

  • Autoimmune Lymphoproliferative Syndrome, Type Ib

  • Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant

  • Css

  • Autoimmune Lymphoproliferative Syndrome, Type 1b

  • Autoimmune Lymphoproliferative Syndrome, Type 1a

  • Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant

  • Fas Deficiency

  • Autoimmune Lymphoproliferative Syndrome 1a

  • ALPS1A

  • Autoimmune Lymphoproliferative Syndrome Type Ia

  • Autoimmune Lymphoproliferative Syndrome 1b

  • ALPS1B

  • Autoimmune Lymphoproliferative Syndrome Type Ib

Scleritis
Autoinflammation, Panniculitis, And Dermatosis Syndrome
  • Otulipenia

  • Otulin-Related Autoinflammatory Syndrome

  • AIPDS

  • Oras

  • Infantile-Onset Periodic Fever-Panniculitis-Dermatosis Syndrome

  • Autoinflammation, Panniculitis And Dermatosis Syndrome

  • Otulin Deficiency

Lymphoproliferative Syndrome
  • Lymphoproliferative Disorder

  • Lymphoproliferative Disorders

  • Lymphoproliferative Disorders, Susceptibility To

Takayasu Arteritis
  • Aortic Arch Syndrome

  • Pulseless Disease

  • Takayasu'S Arteritis

  • Idiopathic Aortitis

  • Young Female Arteritis

  • Aortic Arch Arteritis

  • Aortic Arches Defect

  • Aortic Arch Defects

  • Takayasu Disease

  • Aortic Arch Syndromes

  • Takayasu'S Disease

  • Ta

  • Obliterative Aortitis

  • Aortic Arch Giant-Cell Arteritis

  • Subclavian-Carotid Obstruction Syndrome

  • Idiopathic Medial Aortopathy And Arteriopathy

  • Takayasu Syndrome

  • Obliterative Brachiocephalic Arteritis Syndrome

  • Raeder-Harbitz Syndrome

  • Chronic Subclavian-Carotid Obstruction Syndrome

  • Giant-Cell Aortitis

  • Takayasu Aortitis

  • Nonspecific Aortoarteritis

  • Sclerosing Aortitis And Arteritis

  • Martorell 2 Syndrome

  • Young Female Aortic Arch Arteritis Syndrome

Proteasome-Associated Autoinflammatory Syndrome 1
  • Jmp Syndrome

  • Nakajo-Nishimura Syndrome

  • Nkjo

  • Autoinflammation, Lipodystrophy, And Dermatosis Syndrome

  • Proteasome-Associated Autoinflammatory Syndrome 1 And Digenic Forms

  • Nakajo Syndrome

  • PRAAS1

  • Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature Syndrome

  • Candle

  • Joint Contractures, Muscular Atrophy, Microcytic Anemia, And Panniculitis-Induced Lipodystrophy

  • Aldd

  • Inflammation

  • Joint Contractures - Muscle Atrophy - Microcytic Anemia - Panniculitis-Induced Lipodystrophy

  • Nakajo Nishimura Syndrome

  • Amyotrophy Fat Tissue Anomaly

  • Japanese Autoinflammatory Syndrome With Lipodystrophy

  • Jasl

  • Joint Contractures Muscular Atrophy Microcytic Anemia And Panniculitis-Induced Lipodystrophy

  • Nns

  • Nodular Erythema With Digital Changes

  • Secondary Hypertrophic Osteoperiostosis With Pernio

Alzheimer Disease 5
  • Ad5

  • Alzheimer'S Disease 5

  • Alzheimer Disease, Familial, 5

  • Alzheimer Disease-5

  • Alzheimer Disease, Familial 5

  • Alzheimer'S Disease 5, Late Onset

  • Alzheimer Disease, Familial, Type 5

Primary Mediastinal B-Cell Lymphoma
  • Large Cell Lymphoma Of The Mediastinum

  • Mediastinal Diffuse Large-Cell Lymphoma With Sclerosis

  • Primary Mediastinal Clear Cell Lymphoma Of B-Cell Type

Aphthous Stomatitis
  • Oral Ulcer

  • Canker Sore

  • Aphtha

  • Aphthous Ulceration

  • Oral Aphthae

  • Oral Aphthous Ulcer

  • Canker Sores

  • Stomatitis, Aphthous

  • Minor Oral Aphthous Ulceration

Marginal Zone B-Cell Lymphoma
  • Marginal Zone Lymphoma

  • Mzl

  • Mucosa-Associated Lymphoid Tissue Lymphoma

T-Cell Acute Lymphoblastic Leukemia
  • T-Cell Leukemia

  • Acute T Cell Leukemia

  • Precursor T Lymphoblastic Leukemia

  • Precursor T-Lymphoblastic Lymphoma/Leukemia

  • T Acute Lymphoblastic Leukemia

  • T-Cell Acute Lymphocytic Leukaemia

  • T-Cell Lymphoblastic Leukemia/Lymphoma

  • Leukemia T-Cell

  • Leukemia, T-Cell

  • Leukemia, Acute, Lymphoblastic, T-Cell

  • Leukemia, T-Cell Acute Lymphoblastic

  • Leukemia, Acute T-Cell

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

  • Precursor T-Cell Lymphoblastic Lymphoma

  • Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Nodal Marginal Zone Lymphoma
  • Mucosa-Associated Lymphoid Tissue Lymphoma

  • Monocytoid B-Cell Lymphoma

Spleen Cancer
  • Spleen Neoplasm

  • Splenic Neoplasm

  • Splenic Neoplasms

  • Malignant Splenic Tumor

  • Malignant Tumour Of Spleen

  • Tumor Of Spleen

  • Malignant Neoplasm Of Spleen

Splenic Marginal Zone Lymphoma
  • Smzl

  • Splenic Marginal Zone B-Cell Lymphoma

Autoimmune Disease
  • Autoimmune Diseases

  • Autoimmune Hypersensitivity Disease

  • Hypersensitivity Reaction Type Ii Disease

  • Type Ii Hypersensitivity Reaction Disease

Glycogen Storage Disease Iv
  • Gsd Iv

  • Glycogen Branching Enzyme Deficiency

  • Andersen Disease

  • Amylopectinosis

  • Glycogen Storage Disease Type Iv

  • GSD4

  • Brancher Deficiency

  • Glycogen Storage Disease, Type Iv

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Congenital Neuromuscular Form

  • Gbe1 Deficiency

  • Glycogenosis Iv

  • Cirrhosis, Familial, With Deposition Of Abnormal Glycogen

  • Glycogen Storage Disease Type 4

  • Glycogenosis 4

  • Potassium-Sensitive Periodic Paralysis, Ventricular Ectopy, And Dysmorphic Features

  • Andersen'S Disease

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Childhood Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Fatal Perinatal Neuromuscular Form

  • Brancher Deficiency Glycogenosis

  • Branching-Transferase Deficiency Glycogenosis

  • Deficiency Of 1,4-Alpha-Glucan Branching Enzyme

  • Andersen-Tawil Syndrome

  • Gsd 4

  • Andersen Cardiodysrhythmic Periodic Paralysis

  • Lqt7

  • Long Qt Syndrome 7

  • Periodic Paralysis, Potassium-Sensitive Cardiodysrhythmic Type

  • Andersen Glycogenosis

  • Branching Enzyme Deficiency

  • Glycogenosis, Type Iv

  • Gsd Type Iv

  • Type Iv Glycogenosis

  • Gbe Deficiency, Childhood Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Childhood Neuromuscular Form

  • Gsd Type 4, Childhood Neuromuscular Form

  • Gsdiv, Childhood Neuromuscular Form

  • Glycogen Storage Disease Type 4, Childhood Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Childhood Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Childhood Neuromuscular Form

  • Glycogenosis Type 4, Childhood Neuromuscular Form

  • Glycogenosis Type Iv, Childhood Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Adult Neuromuscular Form

  • Gbe Deficiency, Adult Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Adult Neuromuscular Form

  • Gsd Type 4, Adult Neuromuscular Form

  • Gsdiv, Adult Neuromuscular Form

  • Glycogen Storage Disease Type 4, Adult Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Adult Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Adult Neuromuscular Form

  • Glycogenosis Type 4, Adult Neuromuscular Form

  • Glycogenosis Type Iv, Adult Neuromuscular Form

  • Gbe Deficiency, Congenital Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Congenital Neuromuscular Form

  • Gsd Type 4, Congenital Neuromuscular Form

  • Gsdiv, Congenital Neuromuscular Form

  • Glycogen Storage Disease Type 4, Congenital Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Congenital Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Congenital Neuromuscular Form

  • Glycogenosis Type 4, Congenital Neuromuscular Form

  • Glycogenosis Type Iv, Congenital Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Gbe Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Gsd Type 4, Childhood Combined Hepatic And Myopathic Form

  • Gsdiv, Childhood Combined Hepatic And Myopathic Form

  • Glycogen Storage Disease Type 4, Childhood Combined Hepatic And Myopathic Form

  • Glycogen Storage Disease Type Iv, Childhood Combined Hepatic And Myopathic Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Glycogenosis Type 4, Childhood Combined Hepatic And Myopathic Form

  • Glycogenosis Type Iv, Childhood Combined Hepatic And Myopathic Form

  • Gbe Deficiency, Fatal Perinatal Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Fatal Perinatal Neuromuscular Form

  • Gsd Type 4, Fatal Perinatal Neuromuscular Form

  • Gsdiv, Fatal Perinatal Neuromuscular Form

  • Glycogen Storage Disease Type 4, Fatal Perinatal Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Fatal Perinatal Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Fatal Perinatal Neuromuscular Form

  • Glycogenosis Type 4, Fatal Perinatal Neuromuscular Form

  • Glycogenosis Type Iv, Fatal Perinatal Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Non Progressive Hepatic Form

  • Gbe Deficiency, Non Progressive Hepatic Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Non Progressive Hepatic Form

  • Gsd Type 4, Non Progressive Hepatic Form

  • Gsdiv, Non Progressive Hepatic Form

  • Glycogen Storage Disease Type 4, Non Progressive Hepatic Form

  • Glycogen Storage Disease Type Iv, Non Progressive Hepatic Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Non Progressive Hepatic Form

  • Glycogenosis Type 4, Non Progressive Hepatic Form

  • Glycogenosis Type Iv, Non Progressive Hepatic Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Progressive Hepatic Form

  • Gbe Deficiency, Progressive Hepatic Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Progressive Hepatic Form

  • Gsd Type 4, Progressive Hepatic Form

  • Gsdiv, Progressive Hepatic Form

  • Glycogen Storage Disease Type 4, Progressive Hepatic Form

  • Glycogen Storage Disease Type Iv, Progressive Hepatic Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Progressive Hepatic Form

  • Glycogenosis Type 4, Progressive Hepatic Form

  • Glycogenosis Type Iv, Progressive Hepatic Form

  • Glycogen Storage Disease 4

  • Gsd-Iv

  • Storage Disease, Glycogen, Type Iv

Lymphoma, Mucosa-Associated Lymphoid Type
  • Malt Lymphoma

  • Gastric Lymphoma, Primary

  • Lymphoma, Malt, Somatic

  • Mucosa-Associated Lymphoid Tissue Lymphoma

  • Extranodal Marginal Zone B-Cell Lymphoma

  • MALTOMA

  • Marginal Zone B-Cell Lymphoma

  • Mucosa-Associated Lymphatic Tissue Lymphoma

  • Primary Gastric Lymphoma

  • Gastric Lymphoma

  • Familial Primary Gastric Lymphoma

Psoriasis
Autoimmune Disease Of Cardiovascular System
Behcet Syndrome
  • Behcet Disease

  • Behcet'S Syndrome

  • Behcet'S Disease

  • Behçet Disease

  • Bd

  • Adamantiades-Behcet Disease

  • Triple Symptom Complex

  • Behçet'S Disease

  • Behet'S Syndrome

  • Bd Syndrome

  • Behçet Syndrome

  • Behçet'S Syndrome

  • Behcet Triple Symptom Complex

  • Malignant Aphthosis

  • Old Silk Route Disease

  • Adamantiades-Behçet Disease

Potocki-Shaffer Syndrome
  • Proximal 11p Deletion Syndrome

  • Chromosome 11p11.2 Deletion Syndrome

  • Pss

  • 11p11.2 Deletion

  • P11pds

  • Defect11 Syndrome

  • Deletion Of Chromosome 11p11.2

  • POSHS

Heart Disease
  • Heart Failure

  • Congenital Heart Disease

  • Heart Diseases

  • Congenital Heart Defects

  • Congenital Heart Defect

  • Heart Malformation

  • Congenital Anomaly Of Heart

  • Heart Defect

  • Heart-Congenital Defect

  • Congenital Heart Disorder

  • Heart Defects Congenital

  • Heart Defects, Congenital

  • Heart Defects

  • Heart Disease, Congenital

  • Disease, Heart, Congenital

  • Congestive Heart Failure

Celiac Disease 1
  • Celiac Disease

  • Coeliac Disease

  • Celiac Sprue

  • Celiac Disease, Susceptibility To

  • Gluten-Sensitive Enteropathy

  • Nontropical Sprue

  • Sprue

  • CELIAC1

  • Celiac Disease, Susceptibility To, 1

  • Celiac Sprue 1

  • Celiac Sprue, Susceptibility To, 1

  • Gluten-Sensitive Enteropathy 1

  • Gluten-Sensitive Enteropathy, Susceptibility To, 1

  • Idiopathic Steatorrhea

  • Cœliac Disease

  • Gluten Intolerance

  • Gluten-Induced Enteropathy

  • Gluten Enteropathy

  • Celiac Disease, Susceptibility To, Type 1

  • Childhood Celiac Disease

  • Coeliac Rickets

  • Gee Disease

  • Gee-Herter Disease

  • Heubner-Herter Disease

  • Idiopathic Steatorrhoea

  • Thaysen'S Disease

  • Herter Gee Syndrome

Noonan Syndrome 1
  • Noonan Syndrome

  • NS1

  • Male Turner Syndrome

  • Female Pseudo-Turner Syndrome

  • Turner Phenotype With Normal Karyotype

  • Noonan Syndrome With Pigmented Villonodular Synovitis

  • Turner'S Phenotype, Karyotype Normal

  • Familial Turner Syndrome

  • Noonan'S Syndrome

  • Noonan-Ehmke Syndrome

  • Ns

  • Pseudo-Ullrich-Turner Syndrome

  • Turner Syndrome In Female With X Chromosome

  • Turner-Like Syndrome

  • Ullrich-Noonan Syndrome

  • Noonan-Like/Multiple Giant Cell Lesion Syndrome

  • Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions

  • Pterygium Colli Syndrome

  • Noonan Syndrome, Type 1

  • Turner Syndrome, Male

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta TNFAIP3 VGNC VGNC:78580
Rattus norvegicus TNFAIP3 RGD RGD:1589275
Bos taurus TNFAIP3 VGNC VGNC:36155
Mus musculus TNFAIP3 MGD MGI:1196377
Canis familiaris TNFAIP3 VGNC VGNC:47650
Felis catus TNFAIP3 VGNC VGNC:66398
Others TNFAIP3 NCBI