UTP23 - UTP23 small subunit processome component Gene

Also Known as C8orf53

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84294

Summary

Enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in rRNA processing. Predicted to act upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in thyroid (RPKM 6.0), ovary (RPKM 5.7) and 25 other tissues.

UTP23 Products (1)

mRNA Protein Name
NM_032334.3 NP_115710.2 rRNA-processing protein UTP23 homolog

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
16213212 GOA
enables mRNA 5'-UTR binding IDA
IDA: Inferred from direct assay
16213212 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UTP23 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
UTP23 Q9BRU9 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
UTP23 Q9BRU9 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
UTP23 Q9BRU9 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
Intra
UTP23 Q9BRU9 KRTAP10-9 Homo sapiens P60411
Y2H Array
25416956
Intra
UTP23 Q9BRU9 KRTAP10-5 Homo sapiens P60370
Validated Y2H
25416956
Intra
UTP23 Q9BRU9 KRTAP10-5 Homo sapiens P60370
Y2H Array
25416956
Intra
UTP23 Q9BRU9 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
25416956
Intra
UTP23 Q9BRU9 NFKBID Homo sapiens Q8NI38
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 NFKBID Homo sapiens Q8NI38
Y2H Array
32296183
Intra
UTP23 Q9BRU9 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
UTP23 Q9BRU9 KRT38 Homo sapiens O76015
Y2H Array
32296183
Intra
UTP23 Q9BRU9 KRT38 Homo sapiens O76015
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra
UTP23 Q9BRU9 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra
UTP23 Q9BRU9 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra
UTP23 Q9BRU9 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
UTP23 Q9BRU9 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
UTP23 Q9BRU9 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
UTP23 Q9BRU9 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
UTP23 Q9BRU9 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 TRIB3 Homo sapiens Q96RU7
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 TRIB3 Homo sapiens Q96RU7
Y2H Array
32296183
Intra
UTP23 Q9BRU9 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra
UTP23 Q9BRU9 TCF4 Homo sapiens P15884
Y2H Array
25416956
Intra
UTP23 Q9BRU9 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
UTP23 Q9BRU9 TRIM27 Homo sapiens P14373
Y2H Array
25416956
Intra
UTP23 Q9BRU9 TRIM23 Homo sapiens P36406
Y2H Array
25416956
Intra
UTP23 Q9BRU9 PDE9A Homo sapiens O76083
Validated Y2H
25416956
Intra
UTP23 Q9BRU9 PDE9A Homo sapiens O76083
Y2H Prey Pooling
25416956
Intra
UTP23 Q9BRU9 GRN Homo sapiens P28799
Y2H Prey Pooling
32296183
Intra
UTP23 Q9BRU9 GRN Homo sapiens P28799
Y2H Array
32296183
Intra
UTP23 Q9BRU9 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01190 ATP23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15577 UTP20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15578 UTP25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15579 UTP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21489 Atp23 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28007 Atp23 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99750 Navivumab Inhibitor 99.10% Unkown