ZNF408 - zinc finger protein 408 Gene

Also Known as EVR6; RP72

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 79797

Summary

The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with Other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016]

ZNF408 Products (1)

mRNA Protein Name
NM_001184751.2 NP_001171680.1 zinc finger protein 408 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
15231747 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
14667819 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
23716654 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein 408

  • PR domain zinc finger protein 17

ZNF408 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF408 Q9H9D4 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KRTAP12-2 Homo sapiens P59991
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KRTAP12-2 Homo sapiens P59991
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF792 Homo sapiens Q3KQV3
Validated Y2H
25416956
Intra
ZNF408 Q9H9D4 ZNF792 Homo sapiens Q3KQV3
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZNF792 Homo sapiens Q3KQV3
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF792 Homo sapiens Q3KQV3
Y2H Prey Pooling
25416956
Intra
ZNF408 Q9H9D4 APOBEC3C Homo sapiens Q9NRW3
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 APOBEC3C Homo sapiens Q9NRW3
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 APOBEC3C Homo sapiens Q9NRW3
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 PSTPIP1 Homo sapiens O43586
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 PSTPIP1 Homo sapiens O43586
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZNF526 Homo sapiens Q8TF50
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZNF526 Homo sapiens Q8TF50
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF837 Homo sapiens Q96EG3
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZNF837 Homo sapiens Q96EG3
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF317 Homo sapiens Q96PQ6
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF317 Homo sapiens Q96PQ6
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 SSX2IP Homo sapiens Q9Y2D8
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 SSX2IP Homo sapiens Q9Y2D8
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 EXOSC2 Homo sapiens Q13868
Y2H
15231747
Intra
ZNF408 Q9H9D4 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 PNMA2 Homo sapiens Q9UL42
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 PNMA2 Homo sapiens Q9UL42
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 LSM2 Homo sapiens Q9Y333
Y2H
15231747
Intra
ZNF408 Q9H9D4 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Y2H
18255255
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Y2H Array
25416956
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Y2H
15231747
Intra
ZNF408 Q9H9D4 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra
ZNF408 Q9H9D4 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
25416956
Intra
ZNF408 Q9H9D4 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 CEP70 Homo sapiens Q8NHQ1
Y2H Array
25416956
Intra
ZNF408 Q9H9D4 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 MDFI Homo sapiens Q99750
Y2H Array
19060904
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 MDFI Homo sapiens Q99750
Y2H Pooling
19060904
Intra
ZNF408 Q9H9D4 CEP70 Homo sapiens Q8NHQ1
Y2H Pooling
16189514
Intra
ZNF408 Q9H9D4 ZNF408 Homo sapiens Q9H9D4
Pull Down
18255255
Intra
ZNF408 Q9H9D4 ZNF330 Homo sapiens Q9Y3S2
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 ZNF330 Homo sapiens Q9Y3S2
Y2H
15231747
Intra
ZNF408 Q9H9D4 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZBTB26 Homo sapiens Q9HCK0
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZBTB26 Homo sapiens Q9HCK0
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 ZBTB26 Homo sapiens Q9HCK0
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZBTB9 Homo sapiens Q96C00
Y2H Array
20211142
Intra
ZNF408 Q9H9D4 ZBTB9 Homo sapiens Q96C00
Anti Tag CoIP
33961781
Intra
ZNF408 Q9H9D4 ZBTB9 Homo sapiens Q96C00
Anti Tag CoIP
28514442
Intra
ZNF408 Q9H9D4 KRTAP5-9 Homo sapiens P26371
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KRTAP5-9 Homo sapiens P26371
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KCTD9 Homo sapiens Q7L273
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 KCTD9 Homo sapiens Q7L273
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 SPRED1 Homo sapiens Q7Z699
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 SPRED1 Homo sapiens Q7Z699
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 GPATCH2L Homo sapiens Q9NWQ4
Y2H Prey Pooling
25416956
Intra
ZNF408 Q9H9D4 GPATCH2L Homo sapiens Q9NWQ4
Validated Y2H
25416956
Intra
ZNF408 Q9H9D4 FHL2 Homo sapiens Q14192
Anti Tag CoIP
18255255
Intra
ZNF408 Q9H9D4 FHL2 Homo sapiens Q14192
Y2H
18255255
Intra
ZNF408 Q9H9D4 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 TRIM41 Homo sapiens Q8WV44
Anti Tag CoIP
33961781
Intra
ZNF408 Q9H9D4 TRIM41 Homo sapiens Q8WV44
Anti Tag CoIP
28514442
Intra
ZNF408 Q9H9D4 CALCOCO2 Homo sapiens Q13137
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 DVL3 Homo sapiens Q92997
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 DVL3 Homo sapiens Q92997
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 TRIM23 Homo sapiens P36406
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 LZTS2 Homo sapiens Q9BRK4
Anti Tag CoIP
28514442
Intra
ZNF408 Q9H9D4 LZTS2 Homo sapiens Q9BRK4
Anti Tag CoIP
33961781
Intra
ZNF408 Q9H9D4 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 THAP1 Homo sapiens Q9NVV9
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZBTB8A Homo sapiens Q96BR9
Y2H Pooling
16189514
Intra
ZNF408 Q9H9D4 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZBTB48 Homo sapiens P10074
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 ZBTB48 Homo sapiens P10074
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZC4H2 Homo sapiens Q9NQZ6
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZC4H2 Homo sapiens Q9NQZ6
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 ZC4H2 Homo sapiens Q9NQZ6
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 FHL5 Homo sapiens Q5TD97
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 FHL5 Homo sapiens Q5TD97
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZNF473 Homo sapiens Q8WTR7
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 ZNF473 Homo sapiens Q8WTR7
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
ZNF408 Q9H9D4 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 RBMY1F Homo sapiens Q15415
Y2H Prey Pooling
32296183
Intra
ZNF408 Q9H9D4 RBMY1F Homo sapiens Q15415
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 RALY Homo sapiens Q53GL6
Y2H Array
32296183
Intra
ZNF408 Q9H9D4 RALY Homo sapiens Q53GL6
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16048 ZFPM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown