ZNF473 - zinc finger protein 473 Gene

Also Known as ZN473; ZFP100

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25888

Summary

This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016]
Broad expression in testis (RPKM 14.8), spleen (RPKM 2.3) and 21 other tissues.

ZNF473 Products (1)

mRNA Protein Name
NG_051198.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA 3'-end processing by stem-loop binding and cleavage IDA
IDA: Inferred from direct assay
16714279 GOA
Cellular Component GO Annotation Evidence References Source
located in Cajal body IDA
IDA: Inferred from direct assay
16714279 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF473 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF473 Q8WTR7 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
25416956
Intra
ZNF473 Q8WTR7 KRTAP10-9 Homo sapiens P60411
Y2H Array
25416956
Intra
ZNF473 Q8WTR7 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
Intra
ZNF473 Q8WTR7 rnps1 Homo sapiens D3DU92
Y2H Prey Pooling
25416956
Intra
ZNF473 Q8WTR7 rnps1 Homo sapiens D3DU92
Validated Y2H
25416956
Intra
ZNF473 Q8WTR7 ZNF250 Homo sapiens P15622-3
Validated Y2H
25416956
Intra
ZNF473 Q8WTR7 ZNF250 Homo sapiens P15622-3
Y2H Prey Pooling
25416956
Intra
ZNF473 Q8WTR7 ZNF250 Homo sapiens P15622-3
Y2H Array
25416956
Intra
ZNF473 Q8WTR7 ZNF792 Homo sapiens Q3KQV3
Validated Y2H
25416956
Intra
ZNF473 Q8WTR7 DHX57 Homo sapiens Q6P158
Y2H Array
25416956
Intra
ZNF473 Q8WTR7 ZNF837 Homo sapiens Q96EG3
Validated Y2H
32296183
Intra
ZNF473 Q8WTR7 ZNF408 Homo sapiens Q9H9D4
Validated Y2H
32296183
Intra
ZNF473 Q8WTR7 TRIM41 Homo sapiens Q8WV44
Validated Y2H
32296183
Intra
ZNF473 Q8WTR7 TRIM41 Homo sapiens Q8WV44
Y2H Pooling
16189514
Intra
ZNF473 Q8WTR7 CLK3 Homo sapiens P49761
Validated Y2H
32296183
Intra
ZNF473 Q8WTR7 CLK3 Homo sapiens P49761
Y2H Array
32296183
Intra
ZNF473 Q8WTR7 CLK3 Homo sapiens P49761
Y2H Prey Pooling
32296183
Intra
ZNF473 Q8WTR7 CLK2 Homo sapiens P49760
Validated Y2H
25416956
Intra
ZNF473 Q8WTR7 AEN Homo sapiens Q8WTP8
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16139 ZNF423 Human Pre-designed siRNA Set A Pre-designed Set / Unkown