2. Gene
  3. CLK3 - CDC like kinase 3 Gene

CLK3 - CDC like kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PHCLK3; PHCLK3/152

Gene ID: 1198 | Gene type: protein coding

About CLK3

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,608,372-74,630,201 (from NCBI)

This gene has 27 transcripts (splice variants), 625 orthologues and 12 paralogues. Ubiquitous expression in bone marrow (RPKM 16.0), testis (RPKM 5.8) and 25 other tissues.

Summary

This gene encodes a protein belonging to the serine/threonine type protein kinase family. This protein is a nuclear dual-specificity kinase that regulates the intranuclear distribution of the serine/arginine-rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9. [provided by RefSeq, Jul 2008]

CLK3 Products(2)

mRNA Protein Name
NM_001130028.2 NP_001123500.2 dual specificity protein kinase CLK3
NM_003992.5 NP_003983.2 dual specificity protein kinase CLK3

CLK3 Protein Structure

Pkinase

Pkinase: Protein kinase domain (304 - 620)

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  • 638 a.a.
Protein Preferred Names Protein Names

dual specificity protein kinase CLK3

Recombinant CLK3 Proteins

Cat. No. Product Name Accession Purity
HY-P75678 CLK3 Protein, Human (sf9, GST) P49761-1/NP_003983.2 (M1-R490) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115470 CLK-IN-T3 Inhibitor 98.63% Unkown
HY-112296 T025 98.84% Unkown
HY-15951 ML167 Inhibitor 98.62% Unkown
HY-12828 KH-CB19 Inhibitor 99.31% Unkown
HY-103647 K00546 Inhibitor 98.08% Unkown
HY-137443 Ipivivint Inhibitor 99.65% Unkown
HY-12828A KH-CB20 Inhibitor 99.80% Unkown
HY-117049 Leucettine L41 Inhibitor 98.70% Unkown
HY-155723 Leucettinib-92 Inhibitor / Unkown
HY-RS02818 CLK3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CLK3 VGNC VGNC:60964
Rattus norvegicus CLK3 RGD RGD:621259
Mus musculus CLK3 MGD MGI:1098670
Canis familiaris CLK3 VGNC VGNC:39348
Bos taurus CLK3 VGNC VGNC:27450
Macaca mulatta CLK3 VGNC VGNC:71260