RBMY1A1 - RNA binding motif protein Y-linked family 1 member A1 Gene

Also Known as RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 5940

Summary

This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]

RBMY1A1 Products (1)

mRNA Protein Name
NM_001320945.2 NP_001307874.1 RNA-binding motif protein, Y chromosome, family 1 member A1 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
12165565 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12165565 GOA
Biological Process GO Annotation Evidence References Source
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
12165565 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding motif protein, Y chromosome, family 1 member A1

  • RNA-binding motif protein 2

  • RNA-binding motif protein, Y chromosome, family 1 member A1/C

  • Y chromosome RNA recognition motif 1

  • Y chromosome RNA recognition motif 2

RBMY1A1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RBMY1A1 P0DJD3 PCDHB14 Homo sapiens Q9Y5E9
Y2H Prey Pooling
25416956
Intra
RBMY1A1 P0DJD3 APOBEC3C Homo sapiens Q9NRW3
Y2H Array
25416956
Intra
RBMY1A1 P0DJD3 ZNF317 Homo sapiens Q96PQ6
Y2H Array
31515488
Intra
RBMY1A1 P0DJD3 PRPF31 Homo sapiens Q8WWY3
Y2H Array
25416956
Intra
RBMY1A1 P0DJD3 RBM3 Homo sapiens P98179
Y2H Array
29892012
Intra
RBMY1A1 P0DJD3 HNRNPK Homo sapiens P61978
Y2H Prey Pooling
25416956
Intra
RBMY1A1 P0DJD3 CIRBP Homo sapiens Q14011
Y2H Array
25416956
Intra
RBMY1A1 P0DJD3 TERF1 Homo sapiens P54274
BiFC
21044950
Intra
RBMY1A1 P0DJD3 TERF1 Homo sapiens P54274
Pull Down
21044950
Intra
RBMY1A1 P0DJD3 LNX1 Homo sapiens Q8TBB1
Y2H Prey Pooling
25416956
Intra
RBMY1A1 P0DJD3 LNX1 Homo sapiens Q8TBB1
Y2H Array
29892012
Intra
RBMY1A1 P0DJD3 RBMX Homo sapiens P38159
Validated Y2H
25416956
Intra
RBMY1A1 P0DJD3 RBMX Homo sapiens P38159
Y2H Array
25416956
Intra
RBMY1A1 P0DJD3 CBX2 Homo sapiens Q14781
Y2H Prey Pooling
25416956
Intra
RBMY1A1 P0DJD3 CBX2 Homo sapiens Q14781
Y2H Array
25416956
Intra
RBMY1A1 P0DJD3 AEN Homo sapiens Q8WTP8
Validated Y2H
25416956
Intra
RBMY1A1 P0DJD3 AEN Homo sapiens Q8WTP8
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

RBMY1A1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P86293 RBMY1A1 Antibody (YA5985) WB, IHC-P Human