EAF2 - ELL associated factor 2 Gene

Homo sapiens

Also known as U19; BM040; TRAITS

Gene ID: 55840 | Gene type: protein coding

About EAF2

Cytogenetic location: 3q13.33 Genomic coordinates (GRCh38): 3:121,835,209-121,886,526 (from NCBI)

This gene has 5 transcripts (splice variants), 204 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 6.9), lymph node (RPKM 6.3) and 18 other tissues.

Summary

Enables transcription elongation regulator activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of transcription elongation from RNA polymerase II promoter. Part of transcription elongation factor complex. Biomarker of prostate Cancer. [provided by Alliance of Genome Resources, Apr 2022]

EAF2 Products(2)

mRNA	Protein	Name
NM_001320041.2	NP_001306970.1	ELL-associated factor 2 isoform 2
NM_018456.6	NP_060926.2	ELL-associated factor 2 isoform 1

EAF2 Protein Structure

EAF

0
100
200
260 a.a.

Protein Preferred Names

Protein Names

ELL-associated factor 2

testosterone-regulated apoptosis inducer and tumor suppressor protein

Related Diseases

Diseases

Alias

Eaf

Eosinophilic Angiocentric Fibrosis	Sinonasal Eosinophilic Angiocentric Fibrosis
Igg4-Related Eosinophilic Angiocentric Fibrosis

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04120	EAF2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	EAF2	RGD	RGD:628879
Canis familiaris	EAF2	VGNC	VGNC:40172
Macaca mulatta	EAF2	VGNC	VGNC:71884
Felis catus	EAF2	VGNC	VGNC:61701
Mus musculus	EAF2	MGD	MGI:2146616
Bos taurus	EAF2	VGNC	VGNC:28295