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GMCL2 - germ cell-less 2, spermatogenesis associated Gene

Also Known as GCL; GMCL1L; GMCL1P1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 64396

About GMCL2

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:178,184,505-178,187,371 (from NCBI)

This gene has 1 transcript (splice variant), 211 orthologues and 3 paralogues.

Summary

This locus shares a high degree of identity with the multi-exon germ cell-less gene on chromosome 2. Despite its single-exon nature, this chromosome 5 locus contains an open reading frame that could putatively encode a full-length germ cell-less related protein. [provided by RefSeq, Jul 2008]

GMCL2 Products (1)

mRNA	Protein	Name
NM_001358008.2	NP_001344937.1	germ cell-less protein-like 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables cullin family protein binding	IPI IPI: Inferred from physical interaction	14528312	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
germ cell-less protein-like 2	germ cell-less protein-like 1-like

GMCL2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	GMCL2	Q8NEA9	FLJ13057	Homo sapiens	Q53SE7	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	FLJ13057	Homo sapiens	Q53SE7	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	GAGE12B	Homo sapiens	A1L429	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	UBE2I	Homo sapiens	Q7KZS0	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	UBE2I	Homo sapiens	Q7KZS0	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	UBE2I	Homo sapiens	Q7KZS0	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	BCL11A	Homo sapiens	Q9H165-2	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	BCL11A	Homo sapiens	Q9H165-2	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	GAGE12I	Homo sapiens	P0CL82	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	GAGE12I	Homo sapiens	P0CL82	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	GAGE12I	Homo sapiens	P0CL82	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	LIMS4	Homo sapiens	P0CW20	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	DMWD	Homo sapiens	G5E9A7	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	DMWD	Homo sapiens	G5E9A7	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	DMWD	Homo sapiens	G5E9A7	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	BDNF	Homo sapiens	P23560-2	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	BDNF	Homo sapiens	P23560-2	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	BDNF	Homo sapiens	P23560-2	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	TSC1	Homo sapiens	Q86WV8	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	TSC1	Homo sapiens	Q86WV8	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	TSC1	Homo sapiens	Q86WV8	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	SHQ1	Homo sapiens	Q6PI26	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	LMNA	Homo sapiens	P02545	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	LMNA	Homo sapiens	P02545	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	LMNA	Homo sapiens	P02545	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	GAPDH	Homo sapiens	P04406	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	GAPDH	Homo sapiens	P04406	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	GAPDH	Homo sapiens	P04406	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	KAT5	Homo sapiens	Q92993	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	GMCL2	Q8NEA9	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	GMCL2	Q8NEA9	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	GMCL2	Q8NEA9	BHLHE40	Homo sapiens	O14503	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	BHLHE40	Homo sapiens	O14503	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	TRIM23	Homo sapiens	P36406	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	TRIM23	Homo sapiens	P36406	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	CHCHD3	Homo sapiens	Q9NX63	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	CHCHD3	Homo sapiens	Q9NX63	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	IKZF1	Homo sapiens	Q13422	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	GAGE5	Homo sapiens	Q13069	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	GAGE5	Homo sapiens	Q13069	Y2H Array	25416956
Intra	GMCL2	Q8NEA9	MEOX2	Homo sapiens	P50222	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	MEOX2	Homo sapiens	P50222	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	XAGE2	Homo sapiens	Q96GT9	Y2H Prey Pooling	25416956
Intra	GMCL2	Q8NEA9	XAGE2	Homo sapiens	Q96GT9	Validated Y2H	25416956
Intra	GMCL2	Q8NEA9	GAGE8	Homo sapiens	Q9UEU5	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05514	GMCL2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GMCL2	VGNC	VGNC:107107
Mus musculus	GMCL2	MGD	MGI:1345156