GAGE8 - G antigen 8 Gene

Also Known as CT4.8; GAGE-8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100101629

About GAGE8

Cytogenetic location: Xp11.4-p11.2 Genomic coordinates (GRCh38): X:37,800,001-58,100,000

Summary

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several Other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]

GAGE8 Products (1)

mRNA Protein Name
NM_012196.1 NP_036328.1 G antigen 2D

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G antigen 2D

  • cancer/testis antigen 4.8

GAGE8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GAGE8 Q9UEU5 FLJ13057 Homo sapiens Q53SE7
Y2H Prey Pooling
25416956
Intra
GAGE8 Q9UEU5 FLJ13057 Homo sapiens Q53SE7
Validated Y2H
25416956
Intra
GAGE8 Q9UEU5 FLJ13057 Homo sapiens Q53SE7
Y2H Array
25416956
Intra
GAGE8 Q9UEU5 GMCL2 Homo sapiens Q8NEA9
Validated Y2H
25416956
Intra
GAGE8 Q9UEU5 GMCL2 Homo sapiens Q8NEA9
Pull Down
16189514
Intra
GAGE8 Q9UEU5 GMCL2 Homo sapiens Q8NEA9
Y2H Prey Pooling
25416956
Intra
GAGE8 Q9UEU5 GMCL2 Homo sapiens Q8NEA9
Y2H Pooling
16189514
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS05234 GAGE8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown