BHLHE40 - basic helix-loop-helix family member e40 Gene

Also Known as DEC1; HLHB2; BHLHB2; Clast5; SHARP2; STRA13; Stra14; SHARP-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8553

About BHLHE40

Cytogenetic location: 3p26.1 Genomic coordinates (GRCh38): 3:4,979,437-4,985,323 (from NCBI)

This gene has 3 transcripts (splice variants), 270 orthologues and 12 paralogues. Ubiquitous expression in esophagus (RPKM 152.7), liver (RPKM 106.8) and 25 other tissues.

Summary

This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]

BHLHE40 Products (1)

mRNA Protein Name
NM_003670.3 NP_003661.1 class E basic helix-loop-helix protein 40

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12397359 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12397359 GOA
enables E-box binding IDA
IDA: Inferred from direct assay
12397359 GOA
enables bHLH transcription factor binding IPI
IPI: Inferred from physical interaction
12397359 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
11278694 GOA
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
15560782 GOA
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
12397359 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
15560782 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence References Source
involved in circadian regulation of gene expression IDA
IDA: Inferred from direct assay
18411297 GOA
involved in circadian rhythm IDA
IDA: Inferred from direct assay
28797635 GOA
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
18411297 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12397359 GOA
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
28797635 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12397359 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12624110 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BHLHE40 Protein Structure

HLH

HLH: Helix-loop-helix DNA-binding domain (57 - 107)

Hairy_orange

Hairy_orange: Hairy Orange (140 - 181)

  • 0
  • 100
  • 200
  • 300
  • 412 a.a.
Protein Preferred Names Protein Names

class E basic helix-loop-helix protein 40

  • basic helix-loop-helix domain containing, class B, 2

BHLHE40 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
BHLHE40 O14503 KRTAP23-1 Homo sapiens A1A580
Y2H Array
25416956
Intra
BHLHE40 O14503 STK19 Homo sapiens B7ZLI8
Y2H Array
25416956
Intra
BHLHE40 O14503 AAMP Homo sapiens C9JG97
Y2H Array
25416956
Intra
BHLHE40 O14503 AAMP Homo sapiens C9JG97
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 VENTX Homo sapiens O95231
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 VENTX Homo sapiens O95231
Y2H Array
32296183
Intra
BHLHE40 O14503 VENTX Homo sapiens O95231
Validated Y2H
32296183
Intra
BHLHE40 O14503 ZFHX3 Homo sapiens Q15911-2
Validated Y2H
32296183
Intra
BHLHE40 O14503 ZFHX3 Homo sapiens Q15911-2
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 KRTAP19-7 Homo sapiens Q3SYF9
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra
BHLHE40 O14503 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 LARP4 Homo sapiens Q71RC2-6
Y2H Array
25416956
Intra
BHLHE40 O14503 LARP4 Homo sapiens Q71RC2-6
Validated Y2H
25416956
Intra
BHLHE40 O14503 RBM23 Homo sapiens Q86U06-2
Y2H Array
25416956
Intra
BHLHE40 O14503 GPSM1 Homo sapiens Q86YR5-3
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 GPSM1 Homo sapiens Q86YR5-3
Validated Y2H
32296183
Intra
BHLHE40 O14503 GPSM1 Homo sapiens Q86YR5-3
Y2H Array
32296183
Intra
BHLHE40 O14503 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 KRTAP8-1 Homo sapiens Q8IUC2
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Array
32296183
Intra
BHLHE40 O14503 TXNL4B Homo sapiens Q9NX01
Y2H Array
25416956
Intra
BHLHE40 O14503 TXNL4B Homo sapiens Q9NX01
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 TXNL4B Homo sapiens Q9NX01
Validated Y2H
25416956
Intra
BHLHE40 O14503 KRTAP19-5 Homo sapiens Q3LI72
Y2H Array
32296183
Intra
BHLHE40 O14503 KRTAP19-5 Homo sapiens Q3LI72
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 KRTAP19-5 Homo sapiens Q3LI72
Validated Y2H
32296183
Intra
BHLHE40 O14503 NAA50 Homo sapiens Q9GZZ1
Validated Y2H
32296183
Intra
BHLHE40 O14503 NAA50 Homo sapiens Q9GZZ1
Y2H Array
25416956
Intra
BHLHE40 O14503 NAA50 Homo sapiens Q9GZZ1
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 COX5B Homo sapiens P10606
Y2H Array
31515488
Intra
BHLHE40 O14503 COX5B Homo sapiens P10606
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
Intra
BHLHE40 O14503 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
BHLHE40 O14503 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 LMO3 Homo sapiens Q8TAP4-4
Validated Y2H
32296183
Intra
BHLHE40 O14503 WT1 Homo sapiens P19544-6
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra
BHLHE40 O14503 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 NEK6 Homo sapiens Q9HC98-4
Validated Y2H
32296183
Intra
BHLHE40 O14503 PRKAA1 Homo sapiens Q13131
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra
BHLHE40 O14503 KRTAP6-2 Homo sapiens Q3LI66
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 USP54 Homo sapiens Q70EL1-9
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 USP54 Homo sapiens Q70EL1-9
Validated Y2H
32296183
Intra
BHLHE40 O14503 USP54 Homo sapiens Q70EL1-9
Y2H Array
32296183
Intra
BHLHE40 O14503 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 RBPMS2 Homo sapiens Q6ZRY4
Validated Y2H
32296183
Intra
BHLHE40 O14503 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra
BHLHE40 O14503 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 POU6F2 Homo sapiens P78424
Validated Y2H
32296183
Intra
BHLHE40 O14503 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra
BHLHE40 O14503 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 KRTAP6-1 Homo sapiens Q3LI64
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra
BHLHE40 O14503 RBFOX1 Homo sapiens Q9NWB1-5
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 RBFOX1 Homo sapiens Q9NWB1-5
Validated Y2H
32296183
Intra
BHLHE40 O14503 RBFOX1 Homo sapiens Q9NWB1-5
Y2H Array
32296183
Intra
BHLHE40 O14503 PRR20D Homo sapiens P86480
Y2H Array
32296183
Intra
BHLHE40 O14503 PRR20D Homo sapiens P86480
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 PRR20D Homo sapiens P86480
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 KRTAP19-1 Homo sapiens Q8IUB9
Validated Y2H
32296183
Intra
BHLHE40 O14503 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Array
32296183
Intra
BHLHE40 O14503 CREM Homo sapiens Q03060-25
Y2H Array
32296183
Intra
BHLHE40 O14503 CREM Homo sapiens Q03060-25
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 CREM Homo sapiens Q03060-25
Validated Y2H
32296183
Intra
BHLHE40 O14503 FAM83A Homo sapiens Q86UY5
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 FAM83A Homo sapiens Q86UY5
Validated Y2H
32296183
Intra
BHLHE40 O14503 FAM83A Homo sapiens Q86UY5
Y2H Array
32296183
Intra
BHLHE40 O14503 MTCL2 Homo sapiens O94964-4
Validated Y2H
32296183
Intra
BHLHE40 O14503 VAC14 Homo sapiens Q08AM6
Validated Y2H
32296183
Intra
BHLHE40 O14503 VAC14 Homo sapiens Q08AM6
Y2H Array
25416956
Intra
BHLHE40 O14503 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
Intra
BHLHE40 O14503 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 RHOBTB3 Homo sapiens O94955
Y2H Array
31515488
Intra
BHLHE40 O14503 RHOBTB3 Homo sapiens O94955
Validated Y2H
32296183
Intra
BHLHE40 O14503 RHOBTB3 Homo sapiens O94955
Y2H Array
25416956
Intra
BHLHE40 O14503 TOB2 Homo sapiens Q14106
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 PDE6G Homo sapiens P18545
Y2H Array
25416956
Intra
BHLHE40 O14503 CDPF1 Homo sapiens Q6NVV7
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 CDPF1 Homo sapiens Q6NVV7
Validated Y2H
25416956
Intra
BHLHE40 O14503 CDPF1 Homo sapiens Q6NVV7
Y2H Array
25416956
Intra
BHLHE40 O14503 SMAP2 Homo sapiens Q8WU79
Validated Y2H
32296183
Intra
BHLHE40 O14503 MCRS1 Homo sapiens Q96EZ8
Validated Y2H
32296183
Intra
BHLHE40 O14503 PFDN5 Homo sapiens Q99471
Validated Y2H
32296183
Intra
BHLHE40 O14503 BYSL Homo sapiens Q13895
Validated Y2H
32296183
Intra
BHLHE40 O14503 TP53 Homo sapiens P04637
Imaging
17347673
Intra
BHLHE40 O14503 TP53 Homo sapiens P04637
Pull Down
17347673
Intra
BHLHE40 O14503 TP53 Homo sapiens P04637
Anti Bait CoIP
22723347
Intra
BHLHE40 O14503 TP53 Homo sapiens P04637
Anti Tag CoIP
22723347
Intra
BHLHE40 O14503 PLEKHB2 Homo sapiens Q96CS7
Validated Y2H
25416956
Intra
BHLHE40 O14503 PLEKHB2 Homo sapiens Q96CS7
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 NOC4L Homo sapiens Q9BVI4
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 NOC4L Homo sapiens Q9BVI4
Validated Y2H
25416956
Intra
BHLHE40 O14503 PHF1 Homo sapiens O43189
Validated Y2H
32296183
Intra
BHLHE40 O14503 SOX15 Homo sapiens O60248
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 SOX15 Homo sapiens O60248
Validated Y2H
25416956
Intra
BHLHE40 O14503 SOX15 Homo sapiens O60248
Y2H Array
25416956
Intra
BHLHE40 O14503 RHOJ Homo sapiens Q9H4E5
Y2H Array
25416956
Intra
BHLHE40 O14503 RHOJ Homo sapiens Q9H4E5
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 ROR2 Homo sapiens Q01974
Validated Y2H
32296183
Intra
BHLHE40 O14503 TTC23 Homo sapiens Q5W5X9
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 TTC23 Homo sapiens Q5W5X9
Validated Y2H
25416956
Intra
BHLHE40 O14503 MAGED1 Homo sapiens Q9Y5V3
Y2H Array
32296183
Intra
BHLHE40 O14503 MAGED1 Homo sapiens Q9Y5V3
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 MAGED1 Homo sapiens Q9Y5V3
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 MAGED1 Homo sapiens Q9Y5V3
Validated Y2H
32296183
Intra
BHLHE40 O14503 MAGED1 Homo sapiens Q9Y5V3
Y2H Array
25416956
Intra
BHLHE40 O14503 DAZAP2 Homo sapiens Q15038
Validated Y2H
32296183
Intra
BHLHE40 O14503 DAZAP2 Homo sapiens Q15038
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 DAZAP2 Homo sapiens Q15038
Y2H Array
32296183
Intra
BHLHE40 O14503 DVL3 Homo sapiens Q92997
Validated Y2H
32296183
Intra
BHLHE40 O14503 CCNK Homo sapiens O75909
Y2H Array
25416956
Intra
BHLHE40 O14503 CCNK Homo sapiens O75909
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Intra
BHLHE40 O14503 GMCL2 Homo sapiens Q8NEA9
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 TENT5B Homo sapiens Q96A09
Validated Y2H
32296183
Intra
BHLHE40 O14503 TENT5B Homo sapiens Q96A09
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 TENT5B Homo sapiens Q96A09
Y2H Array
32296183
Intra
BHLHE40 O14503 RBM23 Homo sapiens Q86U06
Y2H Array
25416956
Intra
BHLHE40 O14503 RXRA Homo sapiens P19793
Anti Bait CoIP
29234281
Intra
BHLHE40 O14503 RXRA Homo sapiens P19793
Confocal
29234281
Intra
BHLHE40 O14503 DAB1 Homo sapiens O75553
Validated Y2H
25416956
Intra
BHLHE40 O14503 DAB1 Homo sapiens O75553
Y2H Array
25416956
Intra
BHLHE40 O14503 UBE2I Homo sapiens P63279
Y2H
11278694
Intra
BHLHE40 O14503 SMYD1 Homo sapiens Q8NB12
Y2H Array
29892012
Intra
BHLHE40 O14503 SMYD1 Homo sapiens Q8NB12
Y2H Array
31515488
Intra
BHLHE40 O14503 SMYD1 Homo sapiens Q8NB12
Y2H Prey Pooling
25416956
Intra
BHLHE40 O14503 SMYD1 Homo sapiens Q8NB12
Validated Y2H
25416956
Intra
BHLHE40 O14503 SMYD1 Homo sapiens Q8NB12
Validated Y2H
32296183
Intra
BHLHE40 O14503 SMYD1 Homo sapiens Q8NB12
Y2H Array
25416956
Intra
BHLHE40 O14503 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra
BHLHE40 O14503 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 LASP1 Homo sapiens Q14847-2
Validated Y2H
32296183
Intra
BHLHE40 O14503 ATXN1 Homo sapiens P54253
Validated Y2H
32296183
Intra
BHLHE40 O14503 KLHDC7B Homo sapiens Q96G42
Y2H Array
32296183
Intra
BHLHE40 O14503 KLHDC7B Homo sapiens Q96G42
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 KLHDC7B Homo sapiens Q96G42
Validated Y2H
32296183
Intra
BHLHE40 O14503 RAD54L2 Homo sapiens Q9Y4B4
Y2H Prey Pooling
32296183
Intra
BHLHE40 O14503 RAD54L2 Homo sapiens Q9Y4B4
Validated Y2H
32296183
Intra
BHLHE40 O14503 RAD54L2 Homo sapiens Q9Y4B4
Y2H Array
32296183
Cross
BHLHE40 O14503 rex_htl1c Human T-cell leukemia virus 1 P0C206
Y2H Pooling
22458338
Cross: Cross-species interaction Intra: Intraspecies interaction

BHLHE40 Antibodies

Cat. No. Product Name Application Reactivity
HY-P87071 SHARP2 Antibody (YA6764) WB, IHC-P, ICC/IF Human

Related Diseases

Diseases Alias
Physical Disorder

  • Physical Illness
Tietz Albinism-Deafness Syndrome

  • Tietz Syndrome

  • Albinism-Deafness Of Tietz

  • Hypopigmentation/Deafness Of Tietz

  • Tietze'S Syndrome

  • TADS

  • Costochondral Junction Syndrome

  • Costochondritis

  • Tietze Syndrome

  • Hypopigmentation-Deafness Syndrome

  • Costalchondritis

  • Slipping Rib Syndrome

  • Tietze'S Disease

  • Chondropathia Tuberosa

  • Albinism And Complete Nerve Deafness

  • Tietz'S Syndrome

  • Hypopigmentation-Hearing Loss Syndrome

  • Costal Chondritis

  • Abnormality Of The Costochondral Junction
Septal Myocardial Infarction
Ludwig'S Angina

  • Cellulitis Of Floor Of Mouth

  • Ludwig Angina
Ovarian Melanoma
Fanconi Anemia, Complementation Group I

  • Fanconi Anemia Complementation Group I

  • FANCI
Fanconi Anemia, Complementation Group A

  • Fanconi Anemia

  • Fanconi Pancytopenia

  • Fanconi Anemia Complementation Group A

  • FANCA

  • Fa

  • Fanconi Panmyelopathy

  • Fanconi'S Anemia

  • Fanconi Anaemia

  • Fanconi'S Anaemia

  • Fanconi Hypoplastic Anemia

  • Estren-Dameshek Variant Of Fanconi Anemia

  • Estren-Dameshek Variant Of Fanconi Pancytopenia

  • Fanconi Anemia Estren-Dameshek Variant

  • Fanconis Anemia
Fanconi Anemia, Complementation Group D2

  • Fanconi Anemia Complementation Group D2

  • FANCD2

  • Fad2

  • Fa4

  • Fancd

  • Fanconi Pancytopenia Type 4

  • Fanconi Anemia, Complementation Group D

  • Fanconi Pancytopenia, Type 4

  • Facd

  • Fanconi Anemia Complementation Group D
Deficiency Anemia

  • Anemia

  • Deficiency Anemias

  • Anaemia
Malignant Ovarian Surface Epithelial-Stromal Neoplasm

  • Malignant Ovarian Surface Epithelial-Stromal Tumor
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Head And Neck Cancer

  • Head And Neck Neoplasm

  • Head And Neck Tumours

  • Head/Neck Neoplasm

  • Tumor Of Head And Neck

  • Head And Neck Neoplasms

  • Hnc

  • Cancer, Head/Neck
Aplastic Anemia

  • Aplastic Anemia, Susceptibility To

  • Anemia Aplastic

  • Idiopathic Aplastic Anemia

  • Secondary Aplastic Anemia

  • Idiopathic Bone Marrow Failure

  • Aplastic Anemia Idiopathic

  • AA

  • Anemia, Aplastic

  • Aplastic Anemia, Idiopathic

  • Erythroid Aplasia

  • Aa - [Aplastic Anaemia]

  • Haematopoietic Aplasia

  • Aleukia Haemorrhagica

  • Anaemia Due To Decreased Red Cell Production

  • Aplasia Bone Marrow

  • Aplastic Bone Marrow

  • Hypoplastic Anaemia Nos

  • Myeloid Bone Marrow Aplasia

  • Pancytopenia

  • Panhaematopenia

  • Hypoproliferative Anaemia

  • Medullary Hypoplasia

  • Red Blood Cells Hypoplastic Anaemia

  • Panmyelophthisis

  • Panhemocytopenia

  • Refractive Hypoproliferative Anaemia

  • Toxic Anaemia

  • Toxic Aplastic Anaemia

  • Aplastic Anaemia Due To Toxic Cause

  • Idiopathic Aplastic Anaemia Nos
Leukemia, Acute Myeloid

  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Nervous System Disease

  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder
Skin Disease

  • Skin Diseases

  • Genodermatosis

  • Abnormality Of The Skin

  • Skin Diseases, Genetic

  • Skin And Subcutaneous Tissue Disease

  • Dermatologic Disorders
Connective Tissue Disease

  • Connective Tissue Diseases

  • Connective Tissue Disorder

  • Abnormality Of Connective Tissue

  • Disorder Of Connective Tissue

  • Connective Tissue Disorders
Eye Disease

  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01493 BHLHE40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18433 Bhlhe40 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24914 Bhlhe40 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta BHLHE40 VGNC VGNC:110381
Rattus norvegicus BHLHE40 RGD RGD:68439
Canis familiaris BHLHE40 VGNC VGNC:38446
Bos taurus BHLHE40 VGNC VGNC:26486
Felis catus BHLHE40 VGNC VGNC:69359
Mus musculus BHLHE40 MGD MGI:1097714
Others BHLHE40 NCBI