TTC23 - tetratricopeptide repeat domain 23 Gene

Also Known as HCC-8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64927

Summary

Predicted to be involved in positive regulation of smoothened signaling pathway. Predicted to be located in cilium. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 4.9), ovary (RPKM 4.2) and 24 other tissues.

TTC23 Products (3)

mRNA Protein Name
NM_001288615.3 NP_001275544.1 tetratricopeptide repeat protein 23
NM_001288616.3 NP_001275545.1 tetratricopeptide repeat protein 23
NM_001353869.2 NP_001340798.1 tetratricopeptide repeat protein 23

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TTC23 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TTC23 Q5W5X9 PNMA5 Homo sapiens Q96PV4
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 PNMA5 Homo sapiens Q96PV4
Y2H Array
25416956
Intra
TTC23 Q5W5X9 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
TTC23 Q5W5X9 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 SSX2IP Homo sapiens Q9Y2D8
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 SSX2IP Homo sapiens Q9Y2D8
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 ALAS1 Homo sapiens P13196
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 SPAG5 Homo sapiens Q96R06
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 SPAG5 Homo sapiens Q96R06
Y2H Array
25416956
Intra
TTC23 Q5W5X9 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra
TTC23 Q5W5X9 CREBZF Homo sapiens Q9NS37
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 TRIM10 Homo sapiens Q9UDY6
Y2H Array
31515488
Intra
TTC23 Q5W5X9 TRIM10 Homo sapiens Q9UDY6
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 TRIM10 Homo sapiens Q9UDY6
Y2H Array
25416956
Intra
TTC23 Q5W5X9 BHLHE40 Homo sapiens O14503
Y2H Array
25416956
Intra
TTC23 Q5W5X9 MAGED1 Homo sapiens Q9Y5V3
Y2H Array
25416956
Intra
TTC23 Q5W5X9 MAGED1 Homo sapiens Q9Y5V3
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 MAGED1 Homo sapiens Q9Y5V3
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 MDFI Homo sapiens Q99750
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 MDFI Homo sapiens Q99750
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 MDFI Homo sapiens Q99750
Y2H Array
25416956
Intra
TTC23 Q5W5X9 LDOC1 Homo sapiens O95751
Y2H Array
31515488
Intra
TTC23 Q5W5X9 LDOC1 Homo sapiens O95751
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 LZTS2 Homo sapiens Q9BRK4
Y2H Array
25416956
Intra
TTC23 Q5W5X9 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 TADA2A Homo sapiens O75478
Y2H Array
25416956
Intra
TTC23 Q5W5X9 TADA2A Homo sapiens O75478
Y2H Prey Pooling
25416956
Intra
TTC23 Q5W5X9 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra
TTC23 Q5W5X9 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
TTC23 Q5W5X9 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15197 TTC13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15203 TTC24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15204 TTC26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15205 TTC27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15206 TTC28 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15207 TTC29 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15208 TTC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15209 TTC32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown