TRIM10 - tripartite motif containing 10 Gene

Also Known as RNF9; HERF1; RFB30

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10107

About TRIM10

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:30,151,943-30,164,009 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 96 orthologues and 80 paralogues. Biased expression in bone marrow (RPKM 6.5), kidney (RPKM 1.8) and 6 other tissues.

Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

TRIM10 Products (2)

mRNA Protein Name
NM_006778.4 NP_006769.2 tripartite motif-containing protein 10 isoform 1
NM_052828.3 NP_439893.2 tripartite motif-containing protein 10 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRIM10 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 60)

zf-B_box

zf-B_box: B-box zinc finger (95 - 132)

PRY

PRY: SPRY-associated domain (313 - 359)

  • 0
  • 100
  • 200
  • 300
  • 395 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 10

  • B30-RING finger protein

TRIM10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TRIM10 Q9UDY6 ZNF148 Homo sapiens Q9UQR1
Y2H Prey Pooling
25416956
Intra
TRIM10 Q9UDY6 ZNF148 Homo sapiens Q9UQR1
Validated Y2H
25416956
Intra
TRIM10 Q9UDY6 PSMA1 Homo sapiens P25786
Y2H Prey Pooling
25416956
Intra
TRIM10 Q9UDY6 PSMA1 Homo sapiens P25786
Validated Y2H
25416956
Intra
TRIM10 Q9UDY6 PSMA1 Homo sapiens P25786
Y2H Array
25416956
Intra
TRIM10 Q9UDY6 TTC23 Homo sapiens Q5W5X9
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS15019 TRIM10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TRIM10 MGD MGI:1338757
Canis familiaris TRIM10 VGNC VGNC:49639
Rattus norvegicus TRIM10 RGD RGD:1359438
Bos taurus TRIM10 VGNC VGNC:36312
Macaca mulatta TRIM10 VGNC VGNC:78550
Others TRIM10 NCBI