2. Gene
  3. TRIM10 - tripartite motif containing 10 Gene

TRIM10 - tripartite motif containing 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RNF9; HERF1; RFB30

Gene ID: 10107 | Gene type: protein coding

About TRIM10

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:30,151,943-30,164,009 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 96 orthologues and 80 paralogues. Biased expression in bone marrow (RPKM 6.5), kidney (RPKM 1.8) and 6 other tissues.

Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

TRIM10 Products(2)

mRNA Protein Name
NM_006778.4 NP_006769.2 tripartite motif-containing protein 10 isoform 1
NM_052828.3 NP_439893.2 tripartite motif-containing protein 10 isoform 2

TRIM10 Protein Structure

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 60)

zf-B_box

zf-B_box: B-box zinc finger (95 - 132)

PRY

PRY: SPRY-associated domain (313 - 359)

  • 0
  • 100
  • 200
  • 300
  • 395 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 10

B30-RING finger protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15019 TRIM10 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TRIM10 MGD MGI:1338757
Canis familiaris TRIM10 VGNC VGNC:49639
Rattus norvegicus TRIM10 RGD RGD:1359438
Bos taurus TRIM10 VGNC VGNC:36312
Macaca mulatta TRIM10 VGNC VGNC:78550