SMAP2 - small ArfGAP2 Gene

Homo sapiens

Also known as SMAP1L

Gene ID: 64744 | Gene type: protein coding

About SMAP2

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:40,344,834-40,423,326 (from NCBI)

This gene has 6 transcripts (splice variants), 186 orthologues and 28 paralogues. Broad expression in lymph node (RPKM 80.3), spleen (RPKM 58.9) and 23 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SMAP2 Products(4)

mRNA	Protein	Name
NM_001198978.2	NP_001185907.1	stromal membrane-associated protein 2 isoform 3
NM_001198979.2	NP_001185908.1	stromal membrane-associated protein 2 isoform 2
NM_001198980.1	NP_001185909.1	stromal membrane-associated protein 2 isoform 4
NM_022733.3	NP_073570.1	stromal membrane-associated protein 2 isoform 1

SMAP2 Protein Structure

ArfGap

0
100
200
300
400
429 a.a.

Protein Preferred Names

Protein Names

stromal membrane-associated protein 2

stromal membrane-associated GTPase-activating protein 2

Related Diseases

Diseases

Alias

Spermatogenic Failure 9

Male Infertility Due To Globozoospermia	SPGF9
Male Infertility Due To Round-Headed Spermatozoa	Globozoospermia, Complete
Globozoospermia, Total	Globozoospermia
Globozoospermia Syndrome	Round-Headed Sperm Syndrome
Globozoospermia Complete	Globozoospermia Total

Kniest Dysplasia

Kniest Syndrome	Metatropic Dwarfism, Type Ii
Kniest Chondrodystrophy	Metatropic Dysplasia Type Ii
Swiss Cheese Cartilage Dysplasia	KD
Ks	Metatropic Dwarfism Type Ii
Dysplasia, Kniest

Vitreous Syneresis

Vitreous Degeneration

Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly

Marshall Syndrome

MRSHS	Deafness, Myopia, Cataract, Saddle Nose-Marshall Type
Periodic Fever, Aphthous Stomatitis, Pharyngitis And Adenitis	Pfapa Syndrome
Pfapa	Marshall Syndrome With Periodic Fever
Periodic Fever-Aphtous Stomatitis-Pharyngitis-Adenopathy Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-120272	SMAP-2	Activator	99.63%	Unkown
HY-RS13402	SMAP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SMAP2	VGNC	VGNC:65461
Canis familiaris	SMAP2	VGNC	VGNC:54223
Mus musculus	SMAP2	MGD	MGI:1917030
Macaca mulatta	SMAP2	VGNC	VGNC:77772
Rattus norvegicus	SMAP2	RGD	RGD:1308418
Bos taurus	SMAP2	VGNC	VGNC:34984

Name
Email *

	Sorry, but the email address you supplied was invalid.