LIMS4 - LIM zinc finger domain containing 4 Gene

Also Known as LIMS3L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100288695

Summary

Predicted to enable Actin binding activity and metal ion binding activity. Predicted to be involved in cell surface receptor signaling pathway and positive regulation of signal transduction. Predicted to be located in cytoplasm; focal adhesion; and plasma membrane. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in endometrium (RPKM 15.2), adrenal (RPKM 6.4) and 24 other tissues.

LIMS4 Products (2)

mRNA Protein Name
NM_001205288.2 NP_001192217.1 LIM and senescent cell antigen-like-containing domain protein 4 isoform 1
NM_001371340.3 NP_001358269.1 LIM and senescent cell antigen-like-containing domain protein 4 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LIMS4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LIMS4 P0CW20 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Array
32296183
Intra
LIMS4 P0CW20 KRTAP11-1 Homo sapiens Q8IUC1
Validated Y2H
32296183
Intra
LIMS4 P0CW20 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 C10orf55 Homo sapiens Q5SWW7
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 C10orf55 Homo sapiens Q5SWW7
Validated Y2H
32296183
Intra
LIMS4 P0CW20 C10orf55 Homo sapiens Q5SWW7
Y2H Array
32296183
Intra
LIMS4 P0CW20 TRIM49C Homo sapiens P0CI26
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 TRIM49C Homo sapiens P0CI26
Y2H Array
32296183
Intra
LIMS4 P0CW20 FAM219A Homo sapiens Q8IW50-3
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 FAM219A Homo sapiens Q8IW50-3
Validated Y2H
32296183
Intra
LIMS4 P0CW20 FAM219A Homo sapiens Q8IW50-3
Y2H Array
32296183
Intra
LIMS4 P0CW20 RUSC1 Homo sapiens Q9BVN2
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 RUSC1 Homo sapiens Q9BVN2
Validated Y2H
32296183
Intra
LIMS4 P0CW20 RUSC1 Homo sapiens Q9BVN2
Y2H Array
32296183
Intra
LIMS4 P0CW20 GMCL2 Homo sapiens Q8NEA9
Y2H Prey Pooling
25416956
Intra
LIMS4 P0CW20 GMCL2 Homo sapiens Q8NEA9
Y2H Array
25416956
Intra
LIMS4 P0CW20 CRX Homo sapiens O43186
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 CRX Homo sapiens O43186
Y2H Array
32296183
Intra
LIMS4 P0CW20 BCL6 Homo sapiens P41182
Y2H Prey Pooling
25416956
Intra
LIMS4 P0CW20 BCL6 Homo sapiens P41182
Validated Y2H
32296183
Intra
LIMS4 P0CW20 BCL6 Homo sapiens P41182
Y2H Array
25416956
Intra
LIMS4 P0CW20 KLHDC7B Homo sapiens Q96G42
Y2H Array
32296183
Intra
LIMS4 P0CW20 KLHDC7B Homo sapiens Q96G42
Validated Y2H
32296183
Intra
LIMS4 P0CW20 KLHDC7B Homo sapiens Q96G42
Y2H Prey Pooling
32296183
Intra
LIMS4 P0CW20 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Intra
LIMS4 P0CW20 ARID5A Homo sapiens Q03989
Validated Y2H
32296183
Intra
LIMS4 P0CW20 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07670 LIMS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown