2. Gene
  3. ARID5A - AT-rich interaction domain 5A Gene

ARID5A - AT-rich interaction domain 5A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MRF1; MRF-1; RP11-363D14

Gene ID: 10865 | Gene type: protein coding

About ARID5A

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:96,536,752-96,552,638 (from NCBI)

This gene has 7 transcripts (splice variants), 137 orthologues and 3 paralogues. Ubiquitous expression in bone marrow (RPKM 12.1), appendix (RPKM 8.5) and 24 other tissues.

Summary

Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth (Patsialou et al., 2005 [PubMed 15640446]).[supplied by OMIM, Mar 2008]

ARID5A Products(7)

mRNA Protein Name
NM_001319085.2 NP_001306014.1 AT-rich interactive domain-containing protein 5A isoform a
NM_001319087.2 NP_001306016.1 AT-rich interactive domain-containing protein 5A isoform b
NM_001319092.1 NP_001306021.1 AT-rich interactive domain-containing protein 5A isoform d
NM_001319093.2 NP_001306022.1 AT-rich interactive domain-containing protein 5A isoform e
NM_001319094.2 NP_001306023.1 AT-rich interactive domain-containing protein 5A isoform e
NM_001319096.2 NP_001306025.1 AT-rich interactive domain-containing protein 5A isoform e
NM_212481.3 NP_997646.1 AT-rich interactive domain-containing protein 5A isoform c

ARID5A Protein Structure

ARID

ARID: ARID/BRIGHT DNA binding domain (53 - 142)

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  • 594 a.a.
Protein Preferred Names Protein Names

AT-rich interactive domain-containing protein 5A

ARID domain-containing protein 5A

Related Diseases

Diseases Alias
Currarino Syndrome

Currarino Triad

Partial Sacral Agenesis With Intact First Sacral Vertebra, Presacral Mass And Anorectal Malformation

CURRAS
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N10295 Flavipin Agonist / Unkown
HY-RS00973 ARID5A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ARID5A VGNC VGNC:59918
Bos taurus ARID5A VGNC VGNC:26131
Mus musculus ARID5A MGD MGI:2443039
Rattus norvegicus ARID5A RGD RGD:1311041
Canis familiaris ARID5A VGNC VGNC:38100
Macaca mulatta ARID5A VGNC VGNC:69853