NUDT22 - nudix hydrolase 22 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84304

About NUDT22

This gene has 12 transcripts (splice variants) and 182 orthologues. Ubiquitous expression in duodenum (RPKM 16.3), spleen (RPKM 14.4) and 25 other tissues.

Summary

Enables UDP-sugar diphosphatase activity and metal ion binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NUDT22 Products (4)

mRNA Protein Name
NM_001128612.3 NP_001122084.2 uridine diphosphate glucose pyrophosphatase NUDT22 isoform a
NM_001128613.3 NP_001122085.2 uridine diphosphate glucose pyrophosphatase NUDT22 isoform b
NM_001271831.2 NP_001258760.2 uridine diphosphate glucose pyrophosphatase NUDT22 isoform b
NM_032344.4 NP_115720.2 uridine diphosphate glucose pyrophosphatase NUDT22 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables UDP-sugar diphosphatase activity IDA
IDA: Inferred from direct assay
29413322 GOA
enables metal ion binding IMP
IMP: Inferred from mutant phenotype
29413322 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uridine diphosphate glucose pyrophosphatase NUDT22

  • UDPG pyrophosphatase

NUDT22 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NUDT22 Q9BRQ3 ZNF343 Homo sapiens Q6P1L6
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF343 Homo sapiens Q6P1L6
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 USP54 Homo sapiens Q70EL1-9
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 USP54 Homo sapiens Q70EL1-9
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZNF648 Homo sapiens Q5T619
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF648 Homo sapiens Q5T619
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZMYND12 Homo sapiens Q9H0C1
Validated Y2H
32296183
Intra
NUDT22 Q9BRQ3 ZMYND12 Homo sapiens Q9H0C1
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZMYND12 Homo sapiens Q9H0C1
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
Intra
NUDT22 Q9BRQ3 ZNF19 Homo sapiens P17023
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZNF19 Homo sapiens P17023
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 WDR54 Homo sapiens Q9H977-4
Validated Y2H
32296183
Intra
NUDT22 Q9BRQ3 ZBTB33 Homo sapiens Q86T24
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZBTB33 Homo sapiens Q86T24
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF143 Homo sapiens P52747
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF143 Homo sapiens P52747
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 SAXO1 Homo sapiens Q8IYX7
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 SAXO1 Homo sapiens Q8IYX7
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 RUSC1 Homo sapiens Q9BVN2
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 RUSC1 Homo sapiens Q9BVN2
Complementation
32296183
Intra
NUDT22 Q9BRQ3 RUSC1 Homo sapiens Q9BVN2
Validated Y2H
32296183
Intra
NUDT22 Q9BRQ3 RUSC1 Homo sapiens Q9BVN2
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
Intra
NUDT22 Q9BRQ3 TLE5 Homo sapiens Q08117
Y2H Array
25416956
Intra
NUDT22 Q9BRQ3 KLHL26 Homo sapiens Q53HC5
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 KLHL26 Homo sapiens Q53HC5
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 DNAL4 Homo sapiens O96015
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 DNAL4 Homo sapiens O96015
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF581 Homo sapiens Q9P0T4
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF581 Homo sapiens Q9P0T4
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ZNF581 Homo sapiens Q9P0T4
Validated Y2H
32296183
Intra
NUDT22 Q9BRQ3 ZNF398 Homo sapiens Q8TD17
Y2H Array
32296183
Intra
NUDT22 Q9BRQ3 ZNF398 Homo sapiens Q8TD17
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Intra
NUDT22 Q9BRQ3 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09670 NUDT22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NUDT22 VGNC VGNC:75475
Canis familiaris NUDT22 VGNC VGNC:51884
Bos taurus NUDT22 VGNC VGNC:32337
Felis catus NUDT22 VGNC VGNC:81967
Rattus norvegicus NUDT22 RGD RGD:735224
Mus musculus NUDT22 MGD MGI:1915573
Others NUDT22 NCBI