KLHL26 - kelch like family member 26 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55295

Summary

Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in brain (RPKM 4.1), kidney (RPKM 2.8) and 25 other tissues.

KLHL26 Products (6)

mRNA Protein Name
NM_001345981.2 NP_001332910.1 kelch-like protein 26 isoform 1
NM_001345982.2 NP_001332911.1 kelch-like protein 26 isoform 3
NM_001345983.2 NP_001332912.1 kelch-like protein 26 isoform 4
NM_001345984.2 NP_001332913.1 kelch-like protein 26 isoform 5
NM_001345985.2 NP_001332914.1 kelch-like protein 26 isoform 6
NM_018316.3 NP_060786.1 kelch-like protein 26 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25036637 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KLHL26 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KLHL26 Q53HC5 NUDT22 Homo sapiens Q9BRQ3
Validated Y2H
32296183
Intra
KLHL26 Q53HC5 FOXH1 Homo sapiens O75593
Y2H Array
32296183
Intra
KLHL26 Q53HC5 KCTD9 Homo sapiens Q7L273
Validated Y2H
32296183
Intra
KLHL26 Q53HC5 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
Intra
KLHL26 Q53HC5 NUDCD3 Homo sapiens Q8IVD9
Lumier
25036637
Intra
KLHL26 Q53HC5 NUDCD3 Homo sapiens Q8IVD9
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07361 KLHL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07362 KLHL20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07363 KLHL22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07364 KLHL24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07365 KLHL29 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07370 KLHL6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20437 Klhl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21878 Klhl24 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22601 Klhl6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26946 Klhl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28395 Klhl24 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown