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55295

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By Targets:	E1/E2/E3 Enzyme (1) iGluR (2) Lipoxygenase (1)
By Research Areas:	Infection (1) Inflammation/Immunology (2) Neurological Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-115497

BRD5529 4 Publications Verification	E1/E2/E3 Enzyme	Infection Inflammation/Immunology
BRD5529 is an effective dose-dependent CARD9-TRIM62 protein–protein interaction (PPI) inhibitor with an IC₅₀ value of 8.6 μM. BRD5529 has potency and complete inhibition of CARD9 ubiquitinylation in vitro, also has favorable solubility. BRD5529 can be used for the research of inflammatory bowel disease (IBD) such as Crohn’s disease (CD) and ulcerative colitis (UC) .

HY-19114

WY-50295	Lipoxygenase	Inflammation/Immunology
WY-50295 is an orally active and selective 5-lipoxygenase inhibitor. WY-5029 inhibits LTB4 formation in rat whole blood leukocytes (IC₅₀: 40 μM and oral ED₅₀: 18 mg/kg). WY-50295 can be used in the study of asthma and other leukotriene-dependent diseases .

HY-107696

*Ro 04-5595* hydrochloride**	iGluR	Neurological Disease
Ro 04-5595 hydrochloride is a GluN2B-selective NMDA receptor antagonist (K_i: 31 nM) .

HY-136659

Ro 04-5595	iGluR	Others
Ro 04-5595 is a selective antagonist with specific activity against the NR2B subunit of the NMDA receptor. Ro 04-5595 exhibits favorable pharmacokinetic properties in in vitro and in vivo studies, with rapid uptake and clearance. Ro 04-5595 exhibits strong binding in NR2B receptor-enriched regions and low binding in the cerebellum. Ro 04-5595 is able to effectively inhibit specific binding, showing high affinity for the NR2B receptor and a clear ranking of binding affinity with a variety of other compounds .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700383

	PEX19 Protein, Human (GST) PEX19; peroxisomal biogenesis factor 19; peroxisomal farnesylated protein , PXF; D1S2223E; HK33; housekeeping gene; 33kD; PMP1; PMPI; PXMP1; peroxin-19; housekeeping gene, 33kD; 33 kDa housekeeping protein; peroxisomal farnesylated protein; PXF; FLJ55296	Human	E. coli
	The PEX19 protein is critical in early peroxisome biogenesis, serving as a cytosolic chaperone and import receptor for peroxisomal membrane proteins (PMPs). It binds and stabilizes newly synthesized PMP in the cytoplasm, specifically its hydrophobic domain. PEX19 Protein, Human (GST) is the recombinant human-derived PEX19 protein, expressed by E. coli , with N-GST labeled tag.

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Host:	Mouse (4)
Reactivity:	Human (4) Rat (3) Mouse (3)
Application:	IHC-P (2) ICC/IF (3) IP (1) WB (4) ELISA (3)
Isotype:	IgG1 (1) IgG2a (1)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (4)
Modification:	Unmodified (4)

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HY-P85833

	CD276/B7H3 Antibody (YA5525) CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276	WB, ICC/IF, ELISA	Human, Mouse, Rat
	CD276/B7H3 Antibody (YA5525) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD276/B7H3.

HY-P85603

	FEN1 Antibody (YA5295) DNase IV; FEN-1; FEN1; FEN1_HUMAN; Flap endonuclease 1; Flap structure specific endonuclease 1; Flap structure-specific endonuclease 1; hFEN-1; hFEN1; Maturation factor 1; MF1; Rad2.	WB, IP	Human, Mouse, Rat
	FEN1 Antibody (YA5295) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FEN1.

HY-P85837

	Caldesmon Antibody (YA5529) CAD; CALD 1; CALD1; CALD1_HUMAN; Caldesmon 1; Caldesmon 1 Isoform 1; Caldesmon 1 Isoform 2; Caldesmon 1 Isoform 3; Caldesmon 1 Isoform 4; Caldesmon 1 Isoform 5; Caldesmon; Caldesmon1; CDM; H CAD; HCAD; L CAD; LCAD; MGC21352; NAG22	IHC-P, WB, ICC/IF, ELISA	Human
	Caldesmon Antibody (YA5529) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Caldesmon.

HY-P85903

	Cytokeratin 17 Antibody (YA5595) 39.1; CK 17; CK-17; CytokeRatin-17; K17; K1C17_HUMAN; KeRatin 17; keRatin 17 epitope S1; keRatin 17 epitope S2; keRatin 17 epitope S4; KeRatin 17, type I; KeRatin; KeRatin type I cytoskeletal 17; keRatin, type i cytoskeletal 17 [version 1]; KeRatin-17; KRT17; PC; PC2; PCHC1; type I cytoskeletal 17	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Cytokeratin 17 Antibody (YA5595) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytokeratin 17.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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