ZC3H10 - zinc finger CCCH-type containing 10 Gene
Also Known as ZC3HDC10
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 84872
About ZC3H10
This gene has 5 transcripts (splice variants), 184 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 6.2), ovary (RPKM 4.7) and 25 other tissues.
Summary
Enables miRNA binding activity. Involved in negative regulation of production of miRNAs involved in gene silencing by miRNA and posttranscriptional regulation of gene expression. Predicted to be active in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
ZC3H10 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001303124.2 | NP_001290053.1 | zinc finger CCCH domain-containing protein 10 |
| NM_001303125.2 | NP_001290054.1 | zinc finger CCCH domain-containing protein 10 |
| NM_032786.3 | NP_116175.1 | zinc finger CCCH domain-containing protein 10 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables miRNA binding |
IDA
IDA: Inferred from direct assay
|
28431233 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16189514 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in negative regulation of miRNA processing |
IDA
IDA: Inferred from direct assay
|
28431233 | GOA |
| acts upstream of positive effect post-transcriptional regulation of gene expression |
IDA
IDA: Inferred from direct assay
|
28431233 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
28431233 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
ZC3H10 Protein Structure
zf-CCCH
zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (137 - 159)
- 0
- 100
- 200
- 300
- 400
- 434 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
zinc finger CCCH domain-containing protein 10 |
|
ZC3H10 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
ZC3H10 | Q96K80 | PRR20C | Homo sapiens | P86479 | 25416956 | |
|
Intra
|
ZC3H10 | Q96K80 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP8-1 | Homo sapiens | Q8IUC2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP8-1 | Homo sapiens | Q8IUC2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PICALM | Homo sapiens | Q13492-3 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PICALM | Homo sapiens | Q13492-3 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | NFYA | Homo sapiens | P23511-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | NFYA | Homo sapiens | P23511-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | POU2F1 | Homo sapiens | P14859-6 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | POU2F1 | Homo sapiens | P14859-6 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP6-2 | Homo sapiens | Q3LI66 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP6-2 | Homo sapiens | Q3LI66 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | ACTMAP | Homo sapiens | Q5BKX5-3 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | ACTMAP | Homo sapiens | Q5BKX5-3 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | BOLL | Homo sapiens | Q8N9W6-4 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | BOLL | Homo sapiens | Q8N9W6-4 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RBPMS2 | Homo sapiens | Q6ZRY4 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RBPMS2 | Homo sapiens | Q6ZRY4 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP6-1 | Homo sapiens | Q3LI64 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP6-1 | Homo sapiens | Q3LI64 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | FAM168B | Homo sapiens | A1KXE4-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | FAM168B | Homo sapiens | A1KXE4-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PRR20D | Homo sapiens | P86480 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PRR20D | Homo sapiens | P86480 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | C10orf55 | Homo sapiens | Q5SWW7 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | C10orf55 | Homo sapiens | Q5SWW7 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP19-1 | Homo sapiens | Q8IUB9 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KRTAP19-1 | Homo sapiens | Q8IUB9 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | OXER1 | Homo sapiens | Q8TDS5 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | OXER1 | Homo sapiens | Q8TDS5 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | AOC1 | Homo sapiens | P19801 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | AOC1 | Homo sapiens | P19801 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | FOXH1 | Homo sapiens | O75593 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | FOXH1 | Homo sapiens | O75593 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | FOSB | Homo sapiens | P53539 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | FOSB | Homo sapiens | P53539 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RBM38 | Homo sapiens | Q9H0Z9 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RBM38 | Homo sapiens | Q9H0Z9 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RBM38 | Homo sapiens | Q9H0Z9 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PIAS2 | Homo sapiens | O75928-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PIAS2 | Homo sapiens | O75928-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | STAM2 | Homo sapiens | O75886 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | STAM2 | Homo sapiens | O75886 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | MSX2 | Homo sapiens | P35548 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | MSX2 | Homo sapiens | P35548 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | DAZAP2 | Homo sapiens | Q15038 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | DAZAP2 | Homo sapiens | Q15038 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | DAZAP2 | Homo sapiens | Q15038 | 19060904 | |
|
Intra
|
ZC3H10 | Q96K80 | DAZAP2 | Homo sapiens | Q15038 | 19060904 | |
|
Intra
|
ZC3H10 | Q96K80 | PLA2G10 | Homo sapiens | O15496 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | PLA2G10 | Homo sapiens | O15496 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | RBPMS | Homo sapiens | Q93062 | 25416956 | |
|
Intra
|
ZC3H10 | Q96K80 | APPBP2 | Homo sapiens | Q92624 | 25416956 | |
|
Intra
|
ZC3H10 | Q96K80 | SPMIP9 | Homo sapiens | Q96LM6 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | SPMIP9 | Homo sapiens | Q96LM6 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | SPMIP9 | Homo sapiens | Q96LM6 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | NCS1 | Homo sapiens | P62166 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | NCS1 | Homo sapiens | P62166 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | CRX | Homo sapiens | O43186 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | CRX | Homo sapiens | O43186 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | INTS11 | Homo sapiens | Q5TA45 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | INTS11 | Homo sapiens | Q5TA45 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | TENT5B | Homo sapiens | Q96A09 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | TENT5B | Homo sapiens | Q96A09 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | DAB1 | Homo sapiens | O75553 | 25416956 | |
|
Intra
|
ZC3H10 | Q96K80 | DAB1 | Homo sapiens | O75553 | 25416956 | |
|
Intra
|
ZC3H10 | Q96K80 | OTX2 | Homo sapiens | P32243-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | OTX2 | Homo sapiens | P32243-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | LASP1 | Homo sapiens | Q14847-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | LASP1 | Homo sapiens | Q14847-2 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | ATXN1 | Homo sapiens | P54253 | 16713569 | |
|
Intra
|
ZC3H10 | Q96K80 | ATXN1 | Homo sapiens | P54253 | 16713569 | |
|
Intra
|
ZC3H10 | Q96K80 | ATXN1 | Homo sapiens | P54253 | 23275563 | |
|
Intra
|
ZC3H10 | Q96K80 | KLHDC7B | Homo sapiens | Q96G42 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | KLHDC7B | Homo sapiens | Q96G42 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | ARID5A | Homo sapiens | Q03989 | 32296183 | |
|
Intra
|
ZC3H10 | Q96K80 | ARID5A | Homo sapiens | Q03989 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Optic Atrophy 11 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS15984 | ZC3H10 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | ZC3H10 | VGNC | VGNC:37096 |
| Mus musculus | ZC3H10 | MGD | MGI:2143670 |
| Canis familiaris | ZC3H10 | VGNC | VGNC:48550 |
| Macaca mulatta | ZC3H10 | VGNC | VGNC:79554 |
| Rattus norvegicus | ZC3H10 | RGD | RGD:1587846 |
| Others | ZC3H10 | NCBI |
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